Aqueous vascular endothelial growth factor levels are associated with serous macular detachment secondary to branch retinal vein occlusion

Retina

Volumn 30, Issue 2, 2010, Pages 281-286

  Park, Sung Pyo ^a   Ahn, Jae Kyoun ^b   Mun, Gui Hyeong ^b  

^a Hallym University   (South Korea)

^b Chonnam National University Medical School   (South Korea)

Author keywords

Branch retinal vein occlusion; Cystoid macular edema; Optical coherence tomography; Pigment epithelium derived factor; Serous macular detachment; Vascular endothelial growth factor

Indexed keywords

BEVACIZUMAB; PIGMENT EPITHELIUM DERIVED FACTOR; TRIAMCINOLONE; VASCULOTROPIN;

ADULT; AGED; AQUEOUS HUMOR; ARTICLE; BLOOD VESSEL PERMEABILITY; BRANCH RETINAL VEIN OCCLUSION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OPTICAL COHERENCE TOMOGRAPHY; PROSPECTIVE STUDY; RETINA DETACHMENT; RETINA FLUORESCEIN ANGIOGRAPHY; RETINA ISCHEMIA; RETINA MACULA CYSTOID EDEMA; RETINA MACULA LUTEA; SEROUS RETINAL DETACHMENT; SUBRETINAL FLUID; UPREGULATION; VASCULAR DISEASE; VASCULAR LEAKAGE;

ADULT; AGED; AQUEOUS HUMOR; CAPILLARY PERMEABILITY; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EYE PROTEINS; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; MACULAR EDEMA; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; PROSPECTIVE STUDIES; RETINAL DETACHMENT; RETINAL VEIN OCCLUSION; SERPINS; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY;

EID: 76749119419     PISSN: 0275004X     EISSN: None     Source Type: Journal    
DOI: 10.1097/IAE.0b013e3181b9f153     Document Type: Article

References (22)

1. Gutman FA, Zegarra H. The natural course of temporal retinal vein occlusion. Trans Am Acad Ophthalmol Otolaryngol 1997;78:178-192.
2. Lerche RC, Schaudig U, Scholz F, Walter A, Richard G. Structural changes of the retina in retinal vein occlusion-Imaging and quantification with optical coherence tomography. Ophthalmic Surg Lasers 2001;32:272-280.
3. Yamaguchi Y, Otani T, Kishi S. Serous macular detachment in branch retinal vein occlusion. Retina 2006;26:1029-1033. (Pubitemid 44973222)
4. Spaide RF, Lee JK, Klancnik JM, Gross NE. Optical coherence tomography of branch retinal vein occlusion. Retina 2003;23:343-347.
5. Shroff D, Mehta DK, Arora R, Narula R, Chauhan D. Natural history of macular status in recent-onset branch retinal vein occlusion: an optical coherence tomography study. Int Ophthalmol 2008;28:261-268.
6. Murata T, Ishibashi T, Khalil A, Hata Y, Yoshikawa H, Inomata H. Vascular endothelial growth factor plays a role in hyperpermeability of diabetic retinal vessels. Ophthalmic Res 1995;27:48-52.
7. Péer J, Folberg R, Itin A, Gnessin H, Hemo I, Kesher E. Vascular endothelial growth factor upregulation in human central retinal vein occlusion. Ophthalmology 1998;105:412-416.
8. Park SP, Ahn JK. Changes of aqueous vascular endothelial growth factor and interleukin-6 after intravitreal triamcinolone for branch retinal vein occlusion. Clin Exp Ophthalmol 2008;36:831-835.
9. Noma H, Minamoto A, Funastu H, et al. Intravitreal levels of vascular endothelial growth factor and interleukin-6 are correlated with macular edema in branch retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 2006;244:309-315.
10. Noma H, Funatsu H, Yamasaki M, et al. Pathogenesis of macular edema with branch retinal vein occlusion and intraocular levels of vascular endothelial growth factor and interleukin-6. Am J Ophthalmol 2005;140:256-261.
11. Barnstable CJ, Tombran-Tink J. Neuroprotective and antiangiogenic actions of PEDF in the eye: molecular targets and therapeutic potential. Prog Retin Eye Res 2004;23:561-577.
12. Boehm BO, Lang G, Volpert O, et al. Low content of the natural ocular anti-angiogenic agent pigment epithelium-derived factor (PEDF) in aqueous humor predicts progression of diabetic retinopathy. Diabetologia 2003;46:394-400. (Pubitemid 36547595)
13. Patel JI, Tombran-Tink J, Hykin PG, Gregor ZJ, Cree IA. Vitreous and aqueous concentrations of proangiogenic, antiangiogenic factors and other cytokines in diabetic retinopathy patients with macular edema: implications for structural differences in macular profiles. Exp Eye Res 2006;82:798-806.
14. Noma H, Funatsu H, Yamasaki M, et al. Aqueous humour levels of cytokines are correlated to vitreous levels and severity of macular oedema in branch retinal vein occlusion. Eye 2008;22:42-48.
15. Otani T, Yamaguchi Y, Kishi S. Serous macular detachment secondary to distant retinal vascular disorders. Retina 2004; 24:758-762. (Pubitemid 39391768)
16. Mori K, Duh E, Gehlbach P, et al. Pigment epitheliumderived factor inhibits retinal and choroidal neovascularization. J Cell Physiol 2001;188:253-263.
17. Rehak M, Hollborn M, Iandiev I, et al. Retinal gene expression and Muller cell responses after branch retinal vein occlusion in the rat. Invest Ophthalmol Vis Sci 2009;50:2359-2367.
18. Ohno-Matsui K, Yoshida T, Uetama T, Mochizuki M, Morita I. Vascular endothelial growth factor upregulates pigment epithelium-derived factor expression via VEGFR-1 in human retinal pigment epithelial cells. Biochem Biophys Res Commun 2003;303:962-967.
19. Pai SA, Shetty R, Vijayan PB, et al. Clinical, anatomic, and electrophysiologic evaluation following intravitreal bevacizumab for macular edema in retinal vein occlusion. Am J Ophthalmol 2007;143:601-606.
20. Rabena MD, Pieramici DJ, Castellarin AA, Nasir MA, Avery RL. Intravitreal bevacizumab (Avastin) in the treatment of macular edema secondary to branch retinal vein occlusion. Retina 2007;27:419-425.
21. Kreutzer TC, Alge CS, Wolf AH, et al. Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion. Br J Ophthalmol 2008;92:351-355.
22. Jaissle GB, Leitritz M, Gelisken F, et al. One-year results after intravitreal bevacizumab therapy for macular edema secondary to branch retinal vein occlusion. Graefes Arch Clin Exp Ophthalmol 2009;247:27-33.