Structural determinants of substrate recognition in the HAD superfamily member D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB)

Biochemistry

Volumn 49, Issue 6, 2010, Pages 1082-1092

  Nguyen, Henry H ^a   LiangbingWang, ^b,d   Huang, Hua ^b   Peisach, Ezra ^c   Dunaway Mariano, Debra ^b   Allen, Karen N ^a,c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

^c Boston University   (United States)

^d Chengdu Di'Ao Pharmaceutical Company   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING INTERACTION; BIOCHEMICAL FUNCTIONS; BISPHOSPHATES; CATALYTIC SITES; ENZYME SUPERFAMILIES; HALOALKANOIC ACID DEHALOGENASE; KINETIC ANALYSIS; LEAVING GROUPS; LOOP RESIDUES; PHOSPHOHYDROLASES; STRUCTURAL DETERMINANTS; STRUCTURAL ELEMENTS; STRUCTURE-FUNCTION ANALYSIS; SUBSTRATE RECOGNITION; SUBSTRATE SELECTION; SUBSTRATE SPECIFICITY; SUPPORT SUBSTRATE; X-RAY CRYSTALLOGRAPHIC STRUCTURES;

BINDING ENERGY; BIOINFORMATICS; COMPLEXATION; ESCHERICHIA COLI; PHOSPHATASES;

SUBSTRATES;

GLYCEROMANNOHEPTOSE 1,7 BISPHOSPHATE PHOSPHATASE; HALOALKANOIC ACID DEHALOGENASE; MUTANT PROTEIN; PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; BIOINFORMATICS; BORDETELLA BRONCHISEPTICA; CATALYSIS; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

APOENZYMES; BORDETELLA BRONCHISEPTICA; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HISTIDINOL-PHOSPHATASE; HYDROLASES; MULTIGENE FAMILY; MUTAGENESIS, SITE-DIRECTED; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

BORDETELLA BRONCHISEPTICA; ESCHERICHIA COLI;

EID: 76749115813     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi902019q     Document Type: Article

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