Histological, histochemical and electron microscopic changes of the placenta induced by maternal exposure to hyperthermia in the rat

International Journal of Hyperthermia

Volumn 21, Issue 1, 2005, Pages 29-44

  Padmanabhan, R ^a   Al Menhali, N M ^a   Ahmed, I ^a   Kataya, H H ^a   Ayoub, M A ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Intrauterine growth retardation; Light and electron microscopic studies; Maternal hyperthermia; Placental pathology; Rat embryos

Indexed keywords

AMYLASE; CARMINIC ACID; COLLAGEN; FAT DROPLET; FIBRIN; GLYCOGEN; MYELIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PLACENTA BARRIER; CELL DEGENERATION; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; DATA ANALYSIS; DECIDUA; ELECTRON MICROSCOPY; ENVIRONMENTAL EXPOSURE; EXTRACELLULAR SPACE; FETUS; FIBROSIS; GESTATIONAL AGE; GIANT CELL; HEAT STRESS; HEAT TREATMENT; HISTOCHEMISTRY; HISTOLOGY; HYALINE DEGENERATION; HYPERTHERMIA; INTRAUTERINE GROWTH RETARDATION; LYMPHOCYTIC INFILTRATION; MICROSCOPY; NONHUMAN; PLACENTA; PLACENTA WEIGHT; RAT; STAINING; TEMPERATURE; TROPHOBLAST; VASCULARIZATION;

ANIMALS; CRANIOFACIAL ABNORMALITIES; ENVIRONMENTAL EXPOSURE; FEMALE; FETAL GROWTH RETARDATION; FETUS; FEVER; FIBROSIS; MICROSCOPY, ELECTRON; PLACENTA; PREGNANCY; RATS; RATS, WISTAR; STRESS;

EID: 12344316895     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.1080/02656730410001716614     Document Type: Article

References (70)

1. Dareste C. Reserches sur la production artficielle des monstrrusites, ou essais de tertogenie experimentale. Paris: Reinwald; 1877.
2. Shiota K. Neural tube defects and maternal hyperthermia in early pregnancy: Epidemiology in a human embryo population. Am J Med Genet 1982;12:281-218.
3. Milunsky A, Ulcikas M, Rothman KJ, Willett W, Jick SS, Jick H. Maternal heat exposure and neural tube defects. JAMA 1992;268:882-885.
4. Chambers CD, Johnson KA, Felix RJ, Dick KL, Jones KL. Hyperthermia in pregnancy: A prospective cohort study. Teratology 1997;55:45 (Abst).
5. Poswillo D, Nunnerley H, Sopher D, Keith J. Hyperthermia as a teratogenic agent. Ann Royal Coll Surg Engl 1974;55:171-174.
6. Hendrickx AG, Stone GW, Hendrickson RV, Matayoshi K. Teratogenic effects of hyperthermia in the bonnet monkey (Macaca radiata). Teratology 1979;19:177-182.
7. Kilham L, Ferm VH. Exencephaly in fetal hamsters following exposure to hyperthermia. Teratology 1976;14:323-326.
8. Lary JM, Conover DL, Foley ED, Hanser PL. Teratogenic effects of 27.12 MHz radio frequency in rats. Teratology 1982;26:299-309.
9. Webster WS, Edwards MJ. Hyperthermia and the induction of neural tube defects in mice. Teratology 1984;29:417-425.
10. Germain MA, Webster WS, Edwards MJ. Hyperthermia as a teratogen: Parameters determining hyperthermia-induced head defects in the rat. Teratology 1985;31:265-272.
11. Shiota K. Induction of neural tube defects and skeletal malformations in mice following brief hyperthermia in utero. Biol Neonate 1988;53:86-97.
12. Finnell RH, Moon SP, Abbott LC, Golden JA, Chernoff GF. Strain differences in heat-induced neural tube defects in mice. Teratology 1986;33:247-252.
13. Bennett GD, Mohl VK, Finnell RH. Embryonic and maternal heat shock responses to a teratogenic hyperthermic insult. Reprod Toxicol 1990;4:113-119.
14. Upfold JB, Smith MSR, Edwards MJ. Quantitative study of the effects of maternal hyperthermia on cell death and proliferation in the guinea pig brain on day 21 of pregnancy. Teratology 1989;39:173-179.
15. Walsh DA, Hightower LE, Klein NW, Edwards MJ. The induction of heat shock proteins during early mammalian development. Heat shock, Cold Spring Harbor Laboratory Symposium Vol 2, 1985; 92 (abst).
16. Mirkes PE. Effects of acute exposure to elevated temperature on rat embryo growth and development in vitro. Teratology 1985;32:259-266.
17. Kimmel CA, Cuff JM, Kimmel GL, Heredia DJ, Tudor N, Silverman PM, Chen J. Skeletal development following heat exposure in the rat. Teratology 1993;47:229-242.
18. Edwards MJ, Shiota K, Smith MSR, Walsh DA. Hyperthermia and birth defects. Reprod Toxicol 1995;9:411-425.
19. Webster WS, Germain MA, Edwards MJ. The induction of microphthalmia, encephalocele and other head defects following hyperthermia during the gastrulation process in the rat. Teratology 1985;31:73-82.
20. Walsh DA, Klein NW, Hightower LE, Edwards MJ. Heat shock and thermotolerance during early rat embryo development. Teratology 1987;36:181-191.
21. Harding AJ, Edwards MJ. Microcephaly in rats caused by maternal hyperthermia on days 13 and 14 of pregnancy. Cong Anom 1993;33:203-209.
22. Thayer JM, Mirkes PE. Induction of Hsp72 and transient localization of Hsp73 and Hsp72 correlate with the acquisition and loss of thermoregulation in postimplantation rat embryos. Dev Dyn 1997;208:227-243.
23. Walsh DA, Zhu XO, Grantham J, Taylor R, Inouye M, Edwards MJ. Heat shock proteins in normal and stressed mammalian embryonic development. Con Anom 1998;38:9-23.
24. Adrianakis P, Walker DD, Ralph MM, Thorborn GD. Effect of inhibiting prostaglandin synthesis in pregnant sheep 4-amino antipyrine under normothermic and hypothermic conditions. Am J Obstet Gynecol 1989;161:241-247.
25. Morishima HO, Glaser B, Niemann WH, James LS. Increased uterine activity and fetal deterioration during maternal hyperthermia. Am J Obstet Gynecol 1975;121:531-538.
26. Mirkes PE, Cornel LM, Park HW, Cunningham ML. Induction of thermotolerance in early postimplantation rat embryos is associated with increased resistance to hyperthermia-induced apoptosis. Teratology 1997;56:210-219.
27. Walsh DA, Li K, Wu Y, Nagata K. Heat-shock gene expression and the role of hsps during neural plate induction and early mammalian CNS development. Cell Mol Life Sci 1997;53:198-211.
28. Umpierre CC, Little SA, Mirkes PE. Co-localization of active caspase-3 and DNA fragmentation (TUNEL) in normal and hyperthermia-induced abnormal mouse development. Teratology 2001;63:134-143.
29. Buckiova D, Brown NA. Mechanism of hyperthermia effects on CNS development: Rostral gene expression domains remain, despite severe head truncation; and the hindbrain/otocyst relationship is altered. Teratology 1999;59:139-147.
30. Brent RL, Johnson AJ, Jensen M. The production of congenital malformations using tissue antisera. VII Yolk sac antiserum. Teratology 1971;4:255-276.
31. Reynolds LP, Redmer DA. Utero-placental vascular development and placental function. J Anim Sci 1995;73:1839-1851.
32. Padmanabhan R, Shafiullah, M. Intrauterine growth retardation in experimental diabetes: Possible role of the placenta. Arch Physiol Biochem 2001;109:260-271.
33. Wilson JG. Environment and birth defects. New York: Academic Press; 1973.
34. Abramovici A, Svejcar J. Histochemical and quantitative biochemical changes in mucopolysacharides of the term placenta of the diabetic rat. Placenta 1982;3:81-90.
35. Padmanabhan R. Histological and histochemical changes of placenta in fetal alcohol syndrome due to maternal administration of acute doses of ethanol in the mouse. Drug Alcohol Depend 1985;16:229-239.
36. Khera KS. Maternal toxicity of drugs and metabolic disorders: A possible etiologic factor in the intrauterine death and congenital malformation: A critique on human data. CRC Crit Rev Toxicol 1987;17:345-375.
37. Zusman J, Yaffe P, Ornoy A. The effect of high sucrose diets and maternal diabetes on the ultrastructure of the visceral yolk sac endoderm in rat embryo developing in vivo and in vitro. Acta Anat 1987;128:11-18.
38. Padmanabhan R, Al-Zuhair AGH, Aida H. Histopathological changes of the placenta in diabetes induced by maternal administration of streptozotocin during pregnancy in the rat. Cong Anom 1988;28:1-15.
39. Arora KL, Cohen BJ, Beaudoin AR. Fetal and placental responses to artificially induced hyperthermia in rats. Teratology 1979;19:251-260.
40. Bersu ET, Mossman HW, Kornguth SE. Altered placental morphology associated with murine trisomy 16 and murine trisomy 19. Teratology 1989;40:513-523.
41. Roberts CT, White CA, Wiemer NG, Ramsay A, Robertson SA. Altered placental development in interleukin-10 null mutant mice. Placenta 2003; 24 (Suppl A): S94-S99.
42. Shrader RE, Hirsch KS, Levin J, Hurley LS. Attenuating effect of zinc on abnormal placental morphology in 6-mercaptopurine treated rats. Teratology 1978;17:315-325.
43. Scott JN, Adejokun F. Placental changes due to administration of diethylstilbestrol (DES). Virchows Arch B Cell Pathol Incl Mol Pathol 1980;34:261-267.
44. Gewolb IH, Merdian W, Warshaw JB, Enders AC. Fine structural abnormalities of the placenta in diabetic rats. Diabetes 1986;35:1254-1261.
45. Ishimura R, Ohsako S, Miyabara Y, Sakaue M, Kawakami T, Aoki Y, Yonemoto J, Tohyama C. Increased glycogen content and glucose transporter 3 mRNA level in the placenta of Holtzman rats after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 2002;178:161-171.
46. Kaufman MH, Bard JBL. The Anatomical Basis of Mouse Development. San Diego: Academic Press; 1999. pp. 220-223.
47. Bancroft D, Stevens A. Theory and Practice of Histological techniques. New York: Churchill Livingston; 1977. pp. 148-149.
48. Padmanabhan R, Al-Zuhair AGH. Ultra structural studies on the placenta of streptozotocin induced maternal diabetes in the rat. Z Mikrosk Anat Forsch 1990;104:212-230.
49. Davis J, Glasser SR. Placental changes in rats after fetectomy. Acta Anat 1968;69:542-608.
50. Jollie WP. Fine structural changes in placental labyrinth of the rat with increasing gestational age. J Ultrastruct Res 1964;10:27-47.
51. Jollie WP. Development, morphology, and function of the yolk-sac placenta of laboratory rodents. Teratology 1990;41:361-381.
52. Thureen PJ, Trembler KA, Meschia G, Makowsky EL, Wickening RB. Placental glucose transport in heat-induced fetal growth retardation. Am J Physiol 1992;263:578-585.
53. Bell AW, Wilkening RB, Meschia G. Some aspects of placental function in chronically heat-stressed ewes. J Dev Physiol 1987;9:17-29.
54. Early RJ, McBride BW, Vatnick I, Bell AW. Chronic heat stress on prenatal development in sheep: II. Placental cellularity and metabolism. J Anim Sci 1991;69:3610-3616.
55. Andrianakis P, Walker D. Effect of hyperthermia on uterine and umbilical blood flows in pregnant sheep. Exp Physiol 1994;79:1-13.
56. Bell AW, McBride BW, Slepetis R, Early RJ, Currie WB. Chronic heat stress and prenatal development in sheep: I. Conceptus growth and maternal plasma hormones and metabolites. J Anim Sci 1989;67:3289-3299.
57. Vatnick I, Ignotz G, McBride BW, Bell AW. Effect of heat stress on bovine placental growth in early pregnancy. J Dev Physiol 1991;16:163-166.
58. Gericke GS, Hofmeyr GJ, Labura H, Isaacs H. Does heat damage fetuses? Med Hypotheses 1989;29:275-278.
59. Downs KM, Hellman ER, McHugh J, Barrickman K, Inman KE. Investigation into a role for the primitive streak in development of the murine allantois. Development 2004;131:37-55.
60. Wigglesworth JS. Fetal growth retardation. Animal model: Uterine vessel ligation in the pregnant rat. Am J Pathol 1974;77:347-350.
61. Sreenathan RN, Singh S, Padmanabhan R. Implication of the placenta in acetaldehyde-induced intrauterine growth retardation. Drug Alcohol Depend 1984;13:199-204.
62. Padmanabhan R. The effect of cadmium on placental structure and its relation to fetal malformations in the mouse. Z Mikrosk Anat Forsch 1986;100:419-427.
63. Ashworth CJ, Finch AM, Page KR, Nwagwu MO, McArdle HJ. Causes and consequences of fetal growth retardation in pigs. Reprod Suppl 2001;58:233-246.
64. Chen CP, Bajoria R, Aplin JD. Decreased vascularization and cell proliferation in placentas of intrauterine growth-restricted fetuses with abnormal umbilical artery flow velocity waveforms. Am J Obstet Gynecol 2002;187:764-769.
65. Cuff JM, Kimmel GL, Kimmel CA, Heredia DJ, Tudor N, Chen J. Relationship between abnormal somite development and axial skeletal defects in rats following heat exposure. Teratology 1993;48:259-266.
66. Kim WK, Mirkes PE. Alterations in mitochondrial morphology are associated with hyperthermia-induced apoptosis in early postimplantation mouse embryos. Birth Defects Res Part A Clin Mol Teratol 2003;67:929-940.
67. Tam PPL. The control of somitogenesis in mouse embryos. J Embryol Exp Morphol 1981;65 (Suppl):103-28.
68. Tam PPL, Snow MHL. Proliferation and migration of primordial germ cells during compensatory growth in mouse embryos. J Embryol Exp Morphol 1981;64:133-147.
69. Dewhirst MW, Lora-Michiels M, Viglianti BL, Dewey WC, Repacholi M. Carcinogenic effects of hyperthermia. Int J Hyperthermia 2003;19:236-251.
70. Edwards MJ, Saunders RD, Shiota K. Effects of heat on embryos and fetuses. Int J Hyperthermia 2003;19:295-324.