5′-Nitro-indirubinoxime induces G1 cell cycle arrest and apoptosis in salivary gland adenocarcinoma cells through the inhibition of Notch-1 signaling

Biochimica et Biophysica Acta - General Subjects

Volumn 1800, Issue 3, 2010, Pages 352-358

  Yoon, Ji Hye ^a   Kim, Soo A ^b   Kwon, Seong Min ^a   Park, Jong Hwan ^a   Park, Hee Sae ^c   Kim, Yong Chul ^d   Yoon, Jung Hoon ^a   Ahn, Sang Gun ^a  

^a Chosun University   (South Korea)

^b Dongguk University   (South Korea)

^c Chonnam National University   (South Korea)

^d Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

5 NIO; Apoptosis; Notch 1; Notch 3; Salivary gland adenocarcinoma

Indexed keywords

5' NITRO INDIRUBINOXIME; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; CYTOCHROME C; DELTA1 PROTEIN; DELTA2 PROTEIN; DELTA3 PROTEIN; INDIRUBIN; JAGGED2 PROTEIN; LIGAND; MESSENGER RNA; NOTCH1 RECEPTOR; NOTCH3 RECEPTOR; UNCLASSIFIED DRUG; 5' NITROINDIRUBINOXIME; 5'-NITROINDIRUBINOXIME; INDOLE DERIVATIVE; NOTCH1 PROTEIN, HUMAN; OXIME; PRIMER DNA;

ADENOCARCINOMA; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CARCINOMA CELL; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALIVARY GLAND CARCINOMA; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CANCER CELL; CELL LEVEL; CONFERENCE PAPER; DRUG MECHANISM; PROTEIN EXPRESSION; PROTEIN SECRETION; SALIVARY GLAND ADENOCARCINOMA; CELL CYCLE; CELL DIVISION; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; SALIVARY GLAND TUMOR; TUMOR CELL LINE;

ADENOCARCINOMA; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DNA PRIMERS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INDOLES; OXIMES; PROMOTER REGIONS, GENETIC; RECEPTOR, NOTCH1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SALIVARY GLAND NEOPLASMS;

EID: 76749110762     PISSN: 03044165     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbagen.2009.11.007     Document Type: Article

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