Antimalarial preclinical drug development: A single oral dose of a 5-carbon-linked trioxane dimer plus mefloquine cures malaria-infected mice

Drug Development Research

Volumn 71, Issue 1, 2010, Pages 76-81

  Moon, Deuk Kyu ^a   Singhal, Vandana ^b   Kumar, Nirbhay ^b   Shapiro, Theresa A ^b,c   Posner, Gary H ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antimalarial chemotherapy; Artemisinin combination therapy (ACT); Single oral dose ACT cure; Trioxane dimers

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; ARTEMISININ; DIHYDROARTEMISININ ACETATE; DINITROBENZOATE ESTER; MEFLOQUINE; NITROBENZOATE ESTER; NITROBENZOIC ACID DERIVATIVE; SULFONYLBENZOATE ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; LOW DRUG DOSE; MALARIA; MALE; MOUSE; NONHUMAN; PARASITEMIA; SINGLE DRUG DOSE;

EID: 76749103780     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.20350     Document Type: Article

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