Phaleria macrocarpa suppress nephropathy by increasing renal antioxidant enzyme activity in alloxan-induced diabetic rats

Natural Product Sciences

Volumn 15, Issue 3, 2009, Pages 167-172

  Triastuti, Asih ^a   Park, Hee Juhn ^b   Choi, Jong Won ^c  

^a UII University   (Indonesia)

^b Sangji University   (South Korea)

^c Kyungsung University   (South Korea)

Author keywords

Diabetic nephropathy; Hyperglycemia; Oxidative stress; Phaleria macrocarpa

Indexed keywords

ALLOXAN; ANTIDIABETIC AGENT; ANTIOXIDANT; CATALASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; PHALERIA MACROCARPA EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; KIDNEY DISEASE; KIDNEY HYPERTROPHY; MALE; NONHUMAN; OXIDATIVE STRESS; PHALERIA MACROCARPA; RAT; SPRAGUE DAWLEY RAT; TISSUE LEVEL; UREA NITROGEN BLOOD LEVEL;

EID: 76649109274     PISSN: 12263907     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Aebi, H., Catalase. In "Methods of enzymatic analysis" Vergmeyer, M.U., Academic Press, New York., 2, 673 (1974).
2. Akkus, I., Kalak, S., Vural, H., Caglayan O., Menekse, E., and Can G., Leukocyte lipid peroxidation, superoxide dismutase, glutathione peroxidase and serum and leukocyte vitamin C levels of patients with type II diabetes mellitus. Clin. Chim. Acta., 244, 221-227 (1996).
3. Bansal, R., Ahmad, N., and Kidwai, J.R., Alloxan-glucose interaction: Effect on incorporation of C-leucine into pancreatic islets of rat. Acta Diabetologica Latina, 17, 135-143 (1980).
4. Baynes, J.W. and Thorpe, S.R., Role of oxidative stress in diabetes vascular complications: a new perspective of an old paradigm. Diabetes, 48, 1-9 (1999).
5. Bohlender, H.M., Franke, S., Stein, G., and Wof, G., Advanced glycation end products and the kidney. Am. J. Physiol. Renal. Physiol. 289, F645-F659 (2005).
6. Brownlee, M., Biochemistry and molecular cell biology of diabetic complications, Nature, 414, 813-820 (2001).
7. Bryla, J., Kiersztan, A., and Jagielski, A.K., Promising novel approaches to diabetes mellitus therapy: pharmacological, molecular and cellular insights, Eur. Citizen's. Qual. Life., 1, 137-161 (2003).
8. Ellman, G.L., Tissue sulfhydryl group. Arc. Biochem. Biophys. 237, 1589-95 (1959).
9. Evans, J.L., Goldfine, I.D., Maddux, B.A., and Grodsky, G.M., Oxidative stress and stress-activated signaling pathyways: a unifying hypothesis of type 2 diabetes. Endocr. Rec., 23, 599-622 (2002).
10. Faried, A., Kurnia, D., Faried, L.S., Usman, N., Miyazaki, T., Kato, H., and Kuwano, H., Anticancer effects of gallic acid isolated from Indonesia herbal medicine, Phaleria macrocarpa (Scheff.) Boerl, on human cancer cell lines. Int. J. Oncol., 30, 605-613 (2007).
11. Giardino, I., Edelstein, D., and Brownlee, M., BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells. J. Clin. Invest., 97, 1422-1428 (1996).
12. Gill, P.S. and Wilcox, C.S., NADPH oxidases in the kidney. Antioxid. Redox. Signal., 8, 1597-1607 (2006).
13. Harmanto, N., Conquering Disease in Unison with Mahkota Dewa, Ir. Harmanto (Ed.), p.14 PT Mahkota Dewa Indonesia, North Jakarta 2003.
14. Lowry, O., H., Rosebrough, N.J., Farr, A.L., and Randall, R.J., Protein measurement with folin phenol reagent. J. Biol. Chem., 193, 265-275 (1951).
15. Mahboob, M., Rahman, M.F., and Grover, P., Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients. Singapore Med. J., 46, 322-324 (2005).
16. Marklund S. and Marklund, G., Involvement of the superoxide anion radical in the autooxidation of pyrogallol & convenient assay for superoxide dismutase. Eur. J. Biochem., 47, 469-474 (1974).
17. Mitchell, J.R., Jollow, D.W., Potter, W.Z., Gillette, J.R., and Brodie, B.B., Acetaminophen-induced hepatic necrosis IV. Protective role of glutathione. J. Pharmacol. Exp. Ther., 187, 211-217 (1973).
18. Ohkawa, H., Ohishi, N., and Yaki, K., Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal. Biochem., 95, 351-358 (1979).
19. Oshimi, S., Zaima, K., Matsuno, Y., Hirasawa, Y., Iizuka, T., Studiawan, H., Indrayanto, G., Zaini, N.C., and Morita, H., Studies onthe constituents from the fruits of Phaleria macrocarpa. Nat. Med. (Tokyo). 62, 207-210 (2008).
20. Paglia, E.D. and Valentine, W.N., Studies on the quantitative and qualitative charactrization of erythrocytes glutathione peroxide. J. Lab. Clin. Med,. 70, 158-169 (1967).
21. Robertson, R.P., Harmon, J., Tran, P.O., Tanaka, Y., and Takahashi, H., Glucose toxicity in β-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection. Diabetes, 52, 581-587 (2003).
22. Saufi, A., von Heimendahl, C.B., Alfermann, A.W., and Fuss, E., Stereochemistry of lignans in Phaleria macrocarpa (Scheff.) Boerl. Z. Naturforsch., 63, 13-16 (2008).
23. Stevens, M.J., Redox-based mechanisms in diabetes. Antioxid. Redox. Signal., 7, 1483-1485 (2005).
24. Sugiwati, S., Kardono, L.B.S., and Bintang, M., Alpha-glucosidase inhibitory activity and hypoglycemic effect of Phaleria macrocarpa fruit pericarp extracts by oral administration to rats. J. Applied Sci., 6, 2312-2316 (2006).
25. Triastuti, A, Bachri, M.S., and Choi, J.W., Protective effect of butanol fraction of Phaleria macrocarpa on oxidative stress associated with atreptozotocin induced diabetic mice. International Symposium, Pharmaceutical Society of Korea. PD2-5 (2008).
26. Triastuti, A., Tito, F., and Wibowo, A., Antiangiogenic effect of the ethanolic extract from Phaleria macrocarpa Boerl. fruit on chick embryo chorio allantoic membrane (CAM) induced by BFGF, National Symposium in Medicinal Plants of Indonesia, Solo-Indonesia (2006).
27. Turko I.V., Marcondes, S., and Murad, F., Diabetes-associated nitration of tyrosine and activation of succinyl-CoA:3-oxoacid CoA transferase. Am. J. Physiol. Heart. Circ. Physiol., 281, 2289-2294 (2001).
28. Vinik, A.I. and Vinik, E., Prevention of the complications of diabetes. Am. J. Manag. Care., 9, 63-80 (2003).
29. Wells, B.G., Dipiro, J.T., Schwinghammer, T.L., and Hamilton, C.W., Pharmacotherapy Handbook, McGraw-Hill, pp. 170-181 (2003).
30. West, I.C., Radicals and oxidative stress in diabetes. Diabet Med., 17, 171-180 (2000).
31. Wild, S., Roglic, G., Green, S., Sicree, R., and King, H., Global prevalence of diabetes, estimates for the year 2000 and projections for 2030, Diabetes Care, 27, 1047-1053 (2004).
32. Winarto, W.P., Mahkota Dewa: Budidaya dan pemanfaatan Untuk Obat. Penebar Swadaya, Indonesia (2003).
33. Yamamoto, H., Uchigata, Y., and Okamoto, H., Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Nature, 294, 284-286 (1981).
34. Zhang, Y.B., Xu, X.J., and Liu, H.M., Chemical constituents from Mahkoda Dewa. J. Asian Nat. Prod. Res., 8, 119-123 (2006).