Increase effect of transforming growth factor on eotaxin production by normal cultured dermal fibroblasts stimulated with interleukin-4: Inhibitory effect of suplatast tosilate on eotaxin production

Immunological Investigations

Volumn 39, Issue 2, 2010, Pages 93-102

  Bae, Sang Jae ^a   Lee, Jeong Beom ^b   Shimizu, Kazuhiro ^a   Kuwazuka, Yutaka ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b Soonchunhyang University   (South Korea)

Author keywords

Eotaxin; Fibroblasts; IL 4; Suplatast tosilate; TGF

Indexed keywords

EOTAXIN; INTERLEUKIN 4; MESSENGER RNA; SUPLATAST TOSYLATE; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN ALLERGY; SKIN FIBROBLAST; SKIN INFLAMMATION; UPREGULATION;

ANTI-ALLERGIC AGENTS; ARYLSULFONATES; ASTHMA; CELLS, CULTURED; CHEMOKINE CCL11; CHEMOTACTIC FACTORS, EOSINOPHIL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-4; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; SULFONIUM COMPOUNDS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 76649107913     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820130903496769     Document Type: Article

References (32)

1. Amendt, C., Mann, A., Schirmacher, P., Blessing, M. (2002). Resistance of keratinocytes to TGF beta-mediated growth restriction and apoptosis induction accelerates re-epithelialization in skin wounds. J. Cell. Sci. 15(115):2189-2198.
2. Bae, S. J., Tanaka, Y., Ogawa, F., Takenaka, Y., Shimizu, K., Katayama, I. (2002). Inhibitory effect of Cetirizine on histamine-induced eotaxin production in normal human fibroblasts. Curr. Ther. Res.-Clin. Exper. 63:128-140. (Pubitemid 34208435)
3. Clark, R. A., McCoy, G. A., Folkvord, J. M., McPherson, J. M. (1997). TGF-beta 1 stimulates cultured human fibroblasts to proliferate and produce tissue-like fibroplasia: a fibronectin matrix-dependent event. J. Cell. Physiol. 170(1):69-80.
4. De Faria, I. C., De Faria, E. J., Toro, A. A., Ribeiro, J. D., Bertuzzo, C. S. (2008). Association of TGF-beta1, CD14, IL-4, IL-4R and ADAM33 gene polymorphisms with asthma severity in children and adolescents. J. Pediatr. (Rio J.) 84(3):203-210.
5. Elsner, J., Hochstetter, R., Kimmig, D., Kapp, A. (1999). Human eotaxin represents a potent activator of the respiratory burst of human eosinophils. Euro. J. Immunol. 26:1919-1925.
6. Falanga, V., Zhou, L. H., Takagi, H., Murata, H., Ochoa, S., Martin, T. A., Helfman, T. (1995). Human dermal fibroblast clones derived from single cells are heterogeneous in the production of mRNAs for alpha 1(I) procollagen and transforming growth factor-beta 1. J. Invest. Dermatol. 105(1):27-31.
7. Garcia-Zepeda, E. A., Rothenberg, M. E., Ownbey, R. T., Celestin, J., Leder, P., Luster, A. D. (1996). Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat. Med. 2:449-456.
8. Hanazawa, T., Antuni, J. D., Kharitonov, S. A., Barnes, P. J. (2000). Intranasal administration of eotaxin increases nasal eosinophils and nitric oxide in patients with allergic rhinitis. J. Aller. Clin. Immunol. 105:58-64.
9. Jose, P. J., Griffiths-Johnson, D. A., Collins, P. D. (1994). Eotaxin, a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation. J. Exper. Med. 179:881-887.
10. Kampen, G. T., Stafford, S., Adachi, T. (2000). Eotaxin induces degranulation and chemotaxis of eosinophils through the activation of ERK2 and p38 mitogenactivated protein kinases. Blood 95:1911-1917.
11. Leifeman, K. M. (1991). A current perspective on the role of eosinophils in dermatologic disease. J. Amer. Acad. Dermatol. 24(6):1101-1112.
12. Lévêque, C., Grafte, S., Paysant, J., Soutif, A., Lenormand, B., Vasse, M., Soria, C., Vannier, J. P. (1998). Regulation of interleukin 3 receptor alpha chain (IL-3R alpha) on human monocytes by interleukin (IL)-4, IL-10, IL-13, and transforming growth factor beta (TGF-beta). Cytokine 10(7):487-494.
13. Mochizuki, M., Bartels, J., Mallet, A. I., Christophers, E., Schroder, J. M. (1991). IL-4 induces eotaxin: a possible mechanism of selective eosinophil recruitment in helminth infection and atopy. J. Immunol. 160: 60-68.
14. Ohkawara, Y., Tamura, G., Iwasaki, T., Tanaka, A., Kikuchi, T., Shirato, K. (2000). Activation and transforming growth factor-beta production in eosinophils by hyaluronan. Amer. J. Respir. Cell Mol. Biol. 23(4):444-451.
15. Phipps, S., Ying, S., Wangoo, A., Ong, Y. E., Levi-Schaffer, F., Kay, A. B. (2002). The relationship between allergen-induced tissue eosinophilia and markers of repair and remodeling in human atopic skin. J. Immunol. 169(8):4604-4612.
16. Ponath, P. D., Qin, S., Ringler, D. J. (1996). Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. J. Clin. Invest. 97:604-612.
17. Sano, Y., Miyamoto, T., Makino, S. (1997). Anti-inflammatory effect of suplatast tosilate on mild asthma. Chest 112:862-863.
18. Schramm, C., Herz, U., Podlech, J., Protschka, M., Finotto, S., Reddehase, M. J., Kohler, H., Galle, P. R., Lohse, A. W., Blessing, M. (2003). TGF-beta regulates airway responses via T cells. J. Immunol. 170(3):1313-1319.
19. Shimizu, S., Hattori, R., Majima, Y., Shimizu, T. (2009). Th2 cytokine inhibitor suplatast tosilate inhibits antigen-induced mucus hypersecretion in the nasal epithelium of sensitized rats. Ann. Otol. Rhinol. Laryngol. 118(1):67-72.
20. Suto, H., Mitsuishi, K., Hira, K., Uchida, T., Unno, T., Ogawa, H., Yoshiike, T., Takamori, K. (2000). The effect of suplatast tosilate on immunological parameters for the patients with atopic dermatitis. Allergy 49:1163-1172.
21. Taha, R. A., Minshall, E. M., Leung, D. Y., Boguniewicz, M., Luster, A., Muro, S., Toda, M., Hamid, Q. A. (2000). Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis. Clin. Immunol. 105:892-894.
22. Tamaoki, J., Kondo, M., Sakai, N., Aoshiba, K., Tagaya, E., Nakata, J., Isono, K., Nagai, A. (2000). Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroiddependent asthma: a double-blind randomised study. Lancet 356:273-278.
23. Terada, N., Hamano, N., Nomura T. (2000). Interleukin-13 and tumour necrosis factoralpha synergistically induce eotaxin production in human nasal fibroblasts. Clin. Exper. Allergy 30:348-355.
24. Terui, T., Sano, K., Shirota, H., Kunikata N., Ozawa M., Okada M., Honda M., Tamura, G., Tagami H. (2001). TGF-beta-producing CD4+ mediastinal lymph node cells obtained from mice tracheally tolerized to ovalbumin (OVA) suppress both Th1- and Th2-induced cutaneous inflammatory responses to OVA by different mechanisms. J. Immunol. 167(7):3661-3667.
25. Wenzel, S. E., Trudeau, J. B., Barnes, S., Zhou, X., Cundall, M., Westcott, J. Y., McCord, K., Chu, H. W. (2002). TGF-beta and IL-13 synergistically increase eotaxin-1 production in human airway fibroblasts. J. Immunol. 169(8):4613-4619.
26. Woerly, G., Decot, V., Loiseau, S., Loyens, M., Chihara, J., Ono, N., Capron, M. (2004). CD28 and secretory immunoglobulin A-dependent activation of eosinophils: inhibition of mediator release by the anti-allergic drug, suplatast tosilate. Clin. Exper. Allergy 34(9):1379-1387.
27. Yamaya, H., Basaki, Y., Togawa, M., Kojima, M., Kiniwa, M., Matsuura, N. (1995). Downregulation of Th2 cell-mediated murine peritoneal eosinophilia by antiallergic agents. Life Sci. 56:1647-1654.
28. Yanagihara, Y., Kiniwa, M., Ikizawa, K., Shida, T., Matsuura, N., Koda, A. (1993). Suppression IgE production by IPD-1151T (suplatast tosilate), a new dimetylsulfonium agent: 2. Regulation of human IgE response. Japan. J. Pharmacol. 61:31-39. (Pubitemid 23066665)
29. Yang, D., Howard, O. M., Chen, Q., Oppenheim, J. J. (1999) Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6. J. Immunol. 163(4):1737-1741.
30. Yawalkar, N., Uguccioni, M., Scharer, J., Braunwalder, J., Karlen, S., Dewald, B., Braathen, L. R., Baggiolini, M. J. (1999). Enhanced expression of eotaxin and CCR3 in atopic dermatitis. J. Investig. Dermatol. 113:43-48.
31. Yoshihara, S., Ono, M., Yamada, Y., Fukuda, H., Abe, T., Arisaka, O. (2009). Early suplatast tosilate intervention with for prophylaxis of pediatric atopic asthma: a pilot study. Pediat. Allergy Immunol. 20(5):486-492.
32. Ying, S., Meng, Q., Zeibecoglou, K., Robinson, D. S., Macfarlane, A., Humbert, M., Kay, A. B. (1999). Eosinophil chemotactic chemokines (eotaxin, eotaxin-2, RANTES, monocyte chemoattractant protein-3 [MCP-3], and MCP-4), and C-C chemokine receptor 3 expression in bronchial biopsies from atopic and nonatopic (intrinsic) asthmatics. J. Immunol. 163:6321-6329.