메뉴 건너뛰기




Volumn 23, Issue 2, 2010, Pages 405-412

Phosphoproteomic profiling of arsenite-treated human small airway epithelial cells

Author keywords

Arsenite; Mitogen activated protein kinases; Phosphoproteomic profiling; Phosphor receptor tyrosine kinases

Indexed keywords

ARSENIC TRIOXIDE; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 4; FLT3 LIGAND; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 10; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHO RECEPTOR TYROSINE KINASE; PHOSPHOPROTEIN; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE 1; UNCLASSIFIED DRUG;

EID: 76649102773     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000649     Document Type: Article
Times cited : (8)

References (45)
  • 1
    • 0036118599 scopus 로고    scopus 로고
    • The paradox of arsenite: Molecular mechanisms of cell transformation and chemotherapeutic effects
    • Bode AM and Dong Z: The paradox of arsenite: molecular mechanisms of cell transformation and chemotherapeutic effects. Crit Rev Oncol Hematol 42: 5-24, 2002.
    • (2002) Crit Rev Oncol Hematol , vol.42 , pp. 5-24
    • Bode, A.M.1    Dong, Z.2
  • 2
    • 0035015116 scopus 로고    scopus 로고
    • Genetic toxicology of a paradoxical human carcinogen, arsenite: A review
    • Basu A, Mahata J, Gupta S and Giri AK: Genetic toxicology of a paradoxical human carcinogen, arsenite: a review. Mutat Res 488: 171-194, 2001.
    • (2001) Mutat Res , vol.488 , pp. 171-194
    • Basu, A.1    Mahata, J.2    Gupta, S.3    Giri, A.K.4
  • 6
    • 0033533682 scopus 로고    scopus 로고
    • Arsenite poisoning in the Ganges delta
    • Chowdhury TR, Basu GK, Mandal BK, et al: Arsenite poisoning in the Ganges delta. Nature 401: 545-546, 1999.
    • (1999) Nature , vol.401 , pp. 545-546
    • Chowdhury, T.R.1    Basu, G.K.2    Mandal, B.K.3
  • 7
    • 76649108080 scopus 로고    scopus 로고
    • National Research Council:, National Academy Press, Washington, DC
    • National Research Council: Arsenite in Drinking Water. National Academy Press, Washington, DC, 2000.
    • (2000) Arsenite in Drinking Water
  • 8
    • 0014265743 scopus 로고
    • Prevalence of skin cancer in an endemic area of Chronic arseniteism in Taiwan
    • Tseng WP, Chu HM, How SW, Fong JM, Lin CS and Yeh S: Prevalence of skin cancer in an endemic area of Chronic arseniteism in Taiwan. J Natl Cancer Inst 40: 453-463, 1968.
    • (1968) J Natl Cancer Inst , vol.40 , pp. 453-463
    • Tseng, W.P.1    Chu, H.M.2    How, S.W.3    Fong, J.M.4    Lin, C.S.5    Yeh, S.6
  • 10
    • 13744261256 scopus 로고    scopus 로고
    • Some drinking-water disinfectants and contaminants, including arsenic. Working group on the Evaluation of Carcinogenic Risks to Humans
    • IARC
    • IARC: Some drinking-water disinfectants and contaminants, including arsenic. Working group on the Evaluation of Carcinogenic Risks to Humans. IARC Monogr Eval Carcinog Risks Hum 84: 1-477, 2004.
    • (2004) IARC Monogr Eval Carcinog Risks Hum , vol.84 , pp. 1-477
  • 11
    • 0022341366 scopus 로고
    • Comparison of arsenite-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture
    • Lee TC, Oshimura M and Barrett JC: Comparison of arsenite-induced cell transformation, cytotoxicity, mutation and cytogenetic effects in Syrian hamster embryo cells in culture. Carcinogenesis 6: 1421-1426, 1985.
    • (1985) Carcinogenesis , vol.6 , pp. 1421-1426
    • Lee, T.C.1    Oshimura, M.2    Barrett, J.C.3
  • 12
    • 0032493272 scopus 로고    scopus 로고
    • Mutagenicity of arsenite in mammalian cells: Role of reactive oxygen species
    • Hei TK, Liu SX and Waldren C: Mutagenicity of arsenite in mammalian cells: Role of reactive oxygen species. Proc Natl Acad Sci USA 95: 8103-8107, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8103-8107
    • Hei, T.K.1    Liu, S.X.2    Waldren, C.3
  • 13
    • 0027444614 scopus 로고
    • Induction of chromatid breaks and tetraploidy in Chinese hamster ovary cells by treatment with sodium arsenite during the G2 phase
    • Gurr JR, Lin YC, Ho IC, Jan KY and Lee TC: Induction of chromatid breaks and tetraploidy in Chinese hamster ovary cells by treatment with sodium arsenite during the G2 phase. Mutat Res 319: 135-142, 1993.
    • (1993) Mutat Res , vol.319 , pp. 135-142
    • Gurr, J.R.1    Lin, Y.C.2    Ho, I.C.3    Jan, K.Y.4    Lee, T.C.5
  • 14
    • 0028177360 scopus 로고
    • Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells
    • Wang TS and Huang H: Active oxygen species are involved in the induction of micronuclei by arsenite in XRS-5 cells. Mutagenesis 9: 253-257, 1994.
    • (1994) Mutagenesis , vol.9 , pp. 253-257
    • Wang, T.S.1    Huang, H.2
  • 15
    • 0025171686 scopus 로고
    • Ecological correlation between arsenite level in well water and age-adjusted mortality from malignant neoplasms
    • Chen CJ and Wang CJ: Ecological correlation between arsenite level in well water and age-adjusted mortality from malignant neoplasms. Cancer Res 5: 5470-5474, 1990.
    • (1990) Cancer Res , vol.5 , pp. 5470-5474
    • Chen, C.J.1    Wang, C.J.2
  • 16
    • 0035852735 scopus 로고    scopus 로고
    • Induction of oxyradicals by arsenite: Implication for mechanism of genotoxicity
    • Liu SX, Athar M, Lippai I, Waldren C and Hei TK: Induction of oxyradicals by arsenite: Implication for mechanism of genotoxicity. Proc Natl Acad Sci USA 98: 1643-1648, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1643-1648
    • Liu, S.X.1    Athar, M.2    Lippai, I.3    Waldren, C.4    Hei, T.K.5
  • 17
    • 0029858594 scopus 로고    scopus 로고
    • The tumor promoter arsenite simulates AP-1 activity by inhibiting a JNK phosphatase
    • Cavigelli M, Li WW, Lin A, Su B, Yoshioka K and Karin M: The tumor promoter arsenite simulates AP-1 activity by inhibiting a JNK phosphatase. EMBO J 15: 6269-6279, 1996.
    • (1996) EMBO J , vol.15 , pp. 6269-6279
    • Cavigelli, M.1    Li, W.W.2    Lin, A.3    Su, B.4    Yoshioka, K.5    Karin, M.6
  • 18
    • 0031711448 scopus 로고    scopus 로고
    • Activation of MAPKs in human bronchial epithelial cells exposed to metals
    • Samet JM, Graves LM, Quay J, et al: Activation of MAPKs in human bronchial epithelial cells exposed to metals. Am J Physiol 275: L551-L558, 1998.
    • (1998) Am J Physiol , vol.275
    • Samet, J.M.1    Graves, L.M.2    Quay, J.3
  • 19
    • 33751427435 scopus 로고    scopus 로고
    • Long term low-dose arsenite exposure induces loss of DNA methylation
    • Reichard JF, Schnekenburger M and Puga A: Long term low-dose arsenite exposure induces loss of DNA methylation. Biochem Biophysic Res Commun 352: 188-192, 2007.
    • (2007) Biochem Biophysic Res Commun , vol.352 , pp. 188-192
    • Reichard, J.F.1    Schnekenburger, M.2    Puga, A.3
  • 20
    • 0032776995 scopus 로고    scopus 로고
    • Activation of the EGF receptor signaling: Pathway in human airway epithelial cells exposed to metals
    • Wu W, Graves LM, Jaspers I, Devlin RB, Reed W and Samet JM: Activation of the EGF receptor signaling: pathway in human airway epithelial cells exposed to metals. Am J Physiol 277: L924-L931, 1999.
    • (1999) Am J Physiol , vol.277
    • Wu, W.1    Graves, L.M.2    Jaspers, I.3    Devlin, R.B.4    Reed, W.5    Samet, J.M.6
  • 21
    • 0022806748 scopus 로고
    • Response of experimental animals to human carcinogens: An analysis based upon the IARC monographs programme
    • Wilbourne J, Haroun L, Heseltine E, Kaldor J, Partensky D and Vainio V: Response of experimental animals to human carcinogens: an analysis based upon the IARC monographs programme. Carcinogenesis 7: 1853-1863, 1986.
    • (1986) Carcinogenesis , vol.7 , pp. 1853-1863
    • Wilbourne, J.1    Haroun, L.2    Heseltine, E.3    Kaldor, J.4    Partensky, D.5    Vainio, V.6
  • 22
    • 0347478182 scopus 로고    scopus 로고
    • Proteomic technology and its biomedical applications
    • Lau AT, He QY and Chiu JF: Proteomic technology and its biomedical applications. Acta Biochim Biophys Sin 35: 965-975, 2003.
    • (2003) Acta Biochim Biophys Sin , vol.35 , pp. 965-975
    • Lau, A.T.1    He, Q.Y.2    Chiu, J.F.3
  • 23
    • 12344335521 scopus 로고    scopus 로고
    • Proteomics in human disease: Cancer, heart and infectious diseases
    • Jungblut PR, Zimny-Arndt U, Zeindl-Eberhart E, et al: Proteomics in human disease: cancer, heart and infectious diseases. Electrophoresis 20: 2100-2110, 1999.
    • (1999) Electrophoresis , vol.20 , pp. 2100-2110
    • Jungblut, P.R.1    Zimny-Arndt, U.2    Zeindl-Eberhart, E.3
  • 24
    • 33746083700 scopus 로고    scopus 로고
    • Phosphoproteomics: New insights into cellular signaling
    • Mumby M and Brekken D: Phosphoproteomics: new insights into cellular signaling. Genome Biol 6: 230, 2005.
    • (2005) Genome Biol , vol.6 , pp. 230
    • Mumby, M.1    Brekken, D.2
  • 25
    • 10944225411 scopus 로고    scopus 로고
    • A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation
    • Gembitsky DS, Lawlor K, Jacovina A, Yaneva M and Tempst P: A prototype antibody microarray platform to monitor changes in protein tyrosine phosphorylation. Mol Cell Proteomics 3: 1102-1118, 2004.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 1102-1118
    • Gembitsky, D.S.1    Lawlor, K.2    Jacovina, A.3    Yaneva, M.4    Tempst, P.5
  • 26
    • 17844377872 scopus 로고    scopus 로고
    • Immortalization of human small airway epithelial cells by ectopic expression of telomerase
    • Piao CQ, Liu L, Zhao YL, Balajee AS, Suzuki M and Hei TK: Immortalization of human small airway epithelial cells by ectopic expression of telomerase. Carcinogenesis 26: 725-731, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 725-731
    • Piao, C.Q.1    Liu, L.2    Zhao, Y.L.3    Balajee, A.S.4    Suzuki, M.5    Hei, T.K.6
  • 27
    • 0033193247 scopus 로고    scopus 로고
    • Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells
    • Samet JM, Silbajoris R, Wu W and Graves LM: Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells. Am J Respir Cell Mol Biol 21: 357-364, 1999.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 357-364
    • Samet, J.M.1    Silbajoris, R.2    Wu, W.3    Graves, L.M.4
  • 28
    • 34249075147 scopus 로고    scopus 로고
    • MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • Engelman JA, Zejnullahu K, Mitsudomi T, et al: MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316: 1039-1043, 2007.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 29
    • 39149123785 scopus 로고    scopus 로고
    • Human protein atlas and the use of microarray technologies
    • Hober S and Uhlén M: Human protein atlas and the use of microarray technologies. Curr Opin Biotechnol 19: 30-35, 2008.
    • (2008) Curr Opin Biotechnol , vol.19 , pp. 30-35
    • Hober, S.1    Uhlén, M.2
  • 30
    • 0034844554 scopus 로고    scopus 로고
    • Profiling of differentially expressed genes induced by high linear energy transfer radiation in breast epithelial cells
    • Roy D, Calaf G and Hei TK: Profiling of differentially expressed genes induced by high linear energy transfer radiation in breast epithelial cells. Mol Carcinogen 31: 192-203, 2001.
    • (2001) Mol Carcinogen , vol.31 , pp. 192-203
    • Roy, D.1    Calaf, G.2    Hei, T.K.3
  • 31
    • 48249095483 scopus 로고    scopus 로고
    • Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells
    • Lei T, He QY, Cai, Z, et al: Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells. Proteomics 8: 2420-2429, 2008.
    • (2008) Proteomics , vol.8 , pp. 2420-2429
    • Lei, T.1    He, Q.Y.2    Cai, Z.3
  • 32
    • 40349090035 scopus 로고    scopus 로고
    • Neoplastic transformation of human small airway epithelial cells induced by arsenite
    • Wen G, Calaf GM, Partridge MA, et al: Neoplastic transformation of human small airway epithelial cells induced by arsenite. Mol Med 14: 2-10, 2008.
    • (2008) Mol Med , vol.14 , pp. 2-10
    • Wen, G.1    Calaf, G.M.2    Partridge, M.A.3
  • 33
    • 0347356321 scopus 로고    scopus 로고
    • Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes
    • Tanaka-Kagawa T, Hanioka N, Yoshida H, Jinno H and Ando M: Arsenite and arsenate activate extracellular signal-regulated kinases 1/2 by an epidermal growth factor receptor-mediated pathway in normal human keratinocytes. Br J Dermatol 149: 1116-1127, 2003.
    • (2003) Br J Dermatol , vol.149 , pp. 1116-1127
    • Tanaka-Kagawa, T.1    Hanioka, N.2    Yoshida, H.3    Jinno, H.4    Ando, M.5
  • 34
    • 13244252267 scopus 로고    scopus 로고
    • Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: A role of suppression of the PI3K-AKT pathway
    • Ivanov VN and Hei TK: Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway. Oncogene 24: 616-626, 2005.
    • (2005) Oncogene , vol.24 , pp. 616-626
    • Ivanov, V.N.1    Hei, T.K.2
  • 36
    • 34249060044 scopus 로고    scopus 로고
    • Molecular mechanisms of the diabetogenic effects of arsenite: Inhibition of insulin signaling by arsenite and methylarsonous acid
    • Paul DS, Harmon AW, Devesa V, Thomas DJ and Styblo M: Molecular mechanisms of the diabetogenic effects of arsenite: inhibition of insulin signaling by arsenite and methylarsonous acid. Environ Health Perspect 115: 734-742, 2007.
    • (2007) Environ Health Perspect , vol.115 , pp. 734-742
    • Paul, D.S.1    Harmon, A.W.2    Devesa, V.3    Thomas, D.J.4    Styblo, M.5
  • 37
    • 33846500914 scopus 로고    scopus 로고
    • Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenite exposure
    • Shen J, Liu J, Xie Y, Diwan BA and Waalkes MP: Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenite exposure. Toxicol Sci 95: 313-320, 2007.
    • (2007) Toxicol Sci , vol.95 , pp. 313-320
    • Shen, J.1    Liu, J.2    Xie, Y.3    Diwan, B.A.4    Waalkes, M.P.5
  • 38
    • 34247887332 scopus 로고    scopus 로고
    • Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential
    • Patterson TJ and Rice RH: Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential. Toxicol Appl Pharmacol 221: 119-128, 2007.
    • (2007) Toxicol Appl Pharmacol , vol.221 , pp. 119-128
    • Patterson, T.J.1    Rice, R.H.2
  • 39
    • 33845320477 scopus 로고    scopus 로고
    • Arsenite trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation
    • Wetzler M, Brady MT, Tracy E, et al: Arsenite trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. Clin Cancer Res 12: 6817-6825, 2006.
    • (2006) Clin Cancer Res , vol.12 , pp. 6817-6825
    • Wetzler, M.1    Brady, M.T.2    Tracy, E.3
  • 40
    • 16844362016 scopus 로고    scopus 로고
    • Use of arsenite trioxide in haematological malignancies: Insight into the clinical development of a novel agent
    • Amadori S, Fenaux P, Ludwig H, O'Dwyer M and Sanz M: Use of arsenite trioxide in haematological malignancies: insight into the clinical development of a novel agent. Curr Med Res Opin 21: 403-411, 2005.
    • (2005) Curr Med Res Opin , vol.21 , pp. 403-411
    • Amadori, S.1    Fenaux, P.2    Ludwig, H.3    O'Dwyer, M.4    Sanz, M.5
  • 41
    • 33750314586 scopus 로고    scopus 로고
    • Synergistic effect of arsenite trioxide and Flt3 inhibition on cells with Flt3 internal tandem duplication
    • Takahashi S, Harigae H, Yokoyama H, et al: Synergistic effect of arsenite trioxide and Flt3 inhibition on cells with Flt3 internal tandem duplication. Int J Hematol 84: 256-261, 2006.
    • (2006) Int J Hematol , vol.84 , pp. 256-261
    • Takahashi, S.1    Harigae, H.2    Yokoyama, H.3
  • 42
    • 33646564394 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases mediate arsenite-induced down-regulation of surviving in human lung adenocarcinoma cells
    • Cheng Y, Chang LW and Tsou TC: Mitogen-activated protein kinases mediate arsenite-induced down-regulation of surviving in human lung adenocarcinoma cells. Arch Toxicol 80: 310-318, 2006.
    • (2006) Arch Toxicol , vol.80 , pp. 310-318
    • Cheng, Y.1    Chang, L.W.2    Tsou, T.C.3
  • 43
    • 0037373462 scopus 로고    scopus 로고
    • Caspase activation is accelerated by the inhibition of arsenite-induced, membrane-rafts-dependent AKT activation
    • Hossain K, Akhand AA and Kawamto Y: Caspase activation is accelerated by the inhibition of arsenite-induced, membrane-rafts-dependent AKT activation. Free Radic Biol Med 34: 598-606, 2003.
    • (2003) Free Radic Biol Med , vol.34 , pp. 598-606
    • Hossain, K.1    Akhand, A.A.2    Kawamto, Y.3
  • 44
    • 0035544758 scopus 로고    scopus 로고
    • Arsenite activation of P13K/AKT cell survival pathway is mediated by p38 in cultured human keratinocytes
    • Souza K, Maddock DA, Zhang Q, Chen J, Chiu C, Mehta S and Wan Y: Arsenite activation of P13K/AKT cell survival pathway is mediated by p38 in cultured human keratinocytes. Mol Med 7: 767-772, 2001.
    • (2001) Mol Med , vol.7 , pp. 767-772
    • Souza, K.1    Maddock, D.A.2    Zhang, Q.3    Chen, J.4    Chiu, C.5    Mehta, S.6    Wan, Y.7
  • 45
    • 0038363324 scopus 로고    scopus 로고
    • p38 isoforms have opposite effects on AP-1 dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity
    • Pramanik R, Qi X, Borowicz S, Choubey D, Schultz RM, Han J and Chen G: p38 isoforms have opposite effects on AP-1 dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. J Biol Chem 278: 4831-4839, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 4831-4839
    • Pramanik, R.1    Qi, X.2    Borowicz, S.3    Choubey, D.4    Schultz, R.M.5    Han, J.6    Chen, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.