Effects of protein-bound polysacharide isolated from Acanthopananx senticosus in reducing the toxic effects of cisplatin

Korean Journal of Pharmacognosy

Volumn 38, Issue 2, 2007, Pages 152-156

  Lee, Keyong Ho ^a   Yoon, Won Ho ^b  

^a Kolon Life Science Inc   (South Korea)

^b Seoil University   (South Korea)

Author keywords

Acanthopanax senticosus; Cisplatin; Cytoprotection; Protein bound polysaccharide

Indexed keywords

EID: 76649097599     PISSN: 02533073     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Hoekman, K., van der Vijgh, W.J. and Vermorken, J.B. (1999) Clinical and preclinical modulation of chemotherapy-induced toxicity in patients with cancer. Drugs. 57: 133-155.
2. Diwanay, S., Gautam, M. and Patwardhan, B. (2004) Cytoprotection and immunomodulation in cancer therapy. Curr. Med. Chem. Anticancer Agents 4: 479-490.
3. Shea, M., Koziol, J.A. and Howell, S.B. (1984) Kinetics of sodium thiosulfate, a cisplatin neutralizes Clin. Pharmacol. Then 35: 419-425.
4. Zaki, E.L., Springate, J.E. and Taub, M. (2003) Comparative toxicity of ifosfamide metabolites and protective effect of mesna and amifostine in cultured renal tubule cells. Toxicol. In Vitro 17: 397-402.
5. Springate, J.E. (1997) Ifosfamide metabolite chloroacetaldehyde causes renal dysfunction in vivo. J. Appl. Toxicol. 17: 75-79.
6. Springate, J., Chan, K., Lu, H., Davies, S. and Taub, M. (1999) Toxicity of ifosfamide and its metabolite chloroacetaldehyde in cultured renal tubule cells. In Vitro Cell Dev. Biol. Anim. 35: 314-317
7. Ishikawa, M., Aoki, T, Yomogida, S., Takayanagi, Y. and Sasaki, K. Drug interaction effects on antitumour drugs (XV): Disulfiram as protective agent against cyclophosphamide-induced urotoxicity without compromising antitumour activity in mice. Pharmacol. Toxicol. 74: 255-261.
8. Weiss, G, Loyevsky, M. and Gordeuk, V.R. (1999) Dexrazoxane (ICRF-187). Gen. Pharmacol. 32: 155-158.
9. Kemp, G, Rose, P., Lurain, J., Berman, M., Manetta, A., Roullet, B., Homesley, H., Belpomme, D. and Glick, J. (1996) Amifostine pretreatment for protection against cyclophosphamide-induced and cisplatin-induced toxicities: results of a randomized control trial in patients with advanced ovarian cancer. J. Clin. Oncol. 14: 2101-2112.
10. Grdina, D.J., Kataoka, Y, Basic, I. and Perrin, J. (1992) The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation. Carcinogenesis 13: 811-814.
11. Davis, L. and Kuttan, G (1998) Suppressive effect of cyclophosphamide- induced toxicity by Withania somnifera extract in mice. J. Ethnopharmacol. 62: 209-214.
12. Dhuley, J.N. (1998) Effect of ashwagandha on lipid peroxidation in stress-induced animals. J. Ethnopharmacol. 60: 173-178.
13. Mathew, S. and Kuttan, G (1997) Antioxidant activity of Tinospora cordifolia and its usefulness in the amelioration of cyclophosphamide induced toxicity. J. Exp. Clin. Cancer Res. 16: 407-411.
14. Thatte, U.M. and Dahanukar, S.A. (1988) Comparative study of immunomodulating activity of Indian medicinal plants, lithium carbonate and glucan. Methods Find Exp. Clin. Pharmacol. 10: 639-644.
15. Choi, J.S., Yoon, T.J., Kang, K.R., Lee, K.H., Kim, W.H., Suh, Y.H., Song, J. and Jung, M.H. (2003) Glycoprotein isolated from Acanthopanax senticosus protects against hepatotoxicity induced by acute and chronic alcohol treatment. Biol. Pharm. Bull. 29: 306-314.
16. Korean source
17. Floersheim, GL., Chiodetti, N. and Bieri, A. (1988) Differential radioprotection of bone marrow and tumour cells by zinc aspartate. Br J Radiol. 61: 501-508.
18. Mosmann T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65: 55-63.
19. Heeg, K., Reimann, J., Kabelitz, D., Hardt, C. and Wagner, H. (1985) A rapid colorimetric assay for the determination of IL-2-producing helper T cell frequencies. J. Immunol. Methods. 77: 237-246.
20. Catala, A., Zvara, A., Puskas, L.G and Kitajka, K. (2007) Melatonin-induced gene expression changes and its preventive effects on adriamycin-induced lipid peroxidation in rat liver. J. Pineal. Res. 42: 43-49.
21. Lissoni, P., Barni, S., Mandala, M., Ardizzoia, A., Paolorossi, E, Vaghi, M., Longarini, R., Malugani, F. and Tancini, G (1999) Decreased toxicity and increased efficacy of cancer chemotherapy using the pineal hormone melatonin in metastatic solid tumour patients with poor clinical status. Eur. J. Cancer 35: 1688-1692.