Evolutionary conserved sequence elements with embryonic enhancer activity in the vicinity of the mammalian Sox8 gene

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 3, 2010, Pages 465-471

  Guth, Sabine I E ^a   Bösl, Michael R ^b   Sock, Elisabeth ^a   Wegner, Michael ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

Author keywords

Enhancer; Evolutionary conserved sequence; High mobility group; Neural crest; Peripheral nervous system; Sry

Indexed keywords

BETA GALACTOSIDASE; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX8; TRANSCRIPTION FACTOR SOX9;

ARTICLE; CHROMOSOME 17; DNA FLANKING REGION; EMBRYO DEVELOPMENT; ENHANCER REGION; ENZYME ACTIVITY; EXON; GENE INSERTION SEQUENCE; GENETIC CONSERVATION; INTRON; MESENCHYME; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TRANSGENIC ANIMAL;

ANIMALS; CONSERVED SEQUENCE; EMBRYO, MAMMALIAN; ENHANCER ELEMENTS, GENETIC; EVOLUTION, MOLECULAR; EXONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; MICE; ORGAN SPECIFICITY; SOXE TRANSCRIPTION FACTORS; TRANSGENES;

AVES; MAMMALIA;

EID: 76549125031     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.07.008     Document Type: Article

References (26)

1. Antonellis A., Huynh J.L., Lee-Lin S.-Q., Vinton R.M., Renaud G., Loftus S.K., et al. Identification of neural crest and glial enhancers at the mouse Sox10 locus through transgenesis in zebrafish. PLoS Genet 4 (2008) e1000174
2. Bagheri-Fam S., Barrionuevo F., Dohrmann U., Gunther T., Schule R., Kemler R., et al. Long-range upstream and downstream enhancers control distinct subsets of the complex spatiotemporal Sox9 expression pattern. Dev Biol 291 (2006) 382-397
3. Barrionuevo F., Georg I., Scherthan H., Lecureuil C., Guillou F., Wegner M., et al. Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol 327 (2009) 301-312
4. Chaboissier M.-C., Kobayashi A., Vidal V.I.P., Lützkendorf S., van de Kant H.J.G., Wegner M., et al. Functional analysis of Sox8 and Sox9 during sex determination in the mouse. Development 131 (2004) 1891-1901
5. Deal K.K., Cantrell V.A., Chandler R.L., Saunders T.L., Mortlock D.P., and Southard-Smith E.M. Distant regulatory elements in a Sox10-betaGEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues. Dev Dyn 235 (2006) 1413-1432
6. Fisher S., Grice E.A., Vinton R.M., Bessling S.L., and McCallion A.S. Conservation of RET regulatory function from human to zebrafish without sequence similarity. Science 312 (2006) 276-279
7. Fujino A., Pieretti-Vanmarcke R., Wong A., Donahoe P.K., and Arango N.A. Sexual dimorphism of G-protein subunit Gng13 expression in the cortical region of the developing mouse ovary. Dev Dyn 236 (2007) 1991-1996
8. Guth S.I.E., and Wegner M. Having it both ways: Sox protein function between conservation and innovation. Cell Mol Life Sci 65 (2008) 3000-3018
9. Guth S.I., Schmidt K., Hess A., and Wegner M. Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor. J Lipid Res 50 (2009) 1269-1280
10. Kothary R., Clapoff S., Darling S., Perry M.D., Moran L.A., and Rossant J. Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice. Development 105 (1989) 707-714
11. Maka M., Stolt C.C., and Wegner M. Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol 277 (2005) 155-169
12. O'Bryan M.K., Takada S., Kennedy C.L., Scott G., Harada S., Ray M.K., et al. Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol 316 (2008) 359-370
13. Peterfy M., Ben-Zeev O., Mao H.Z., Weissglas-Volkov D., Aouizerat B.E., Pullinger C.R., et al. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet 39 (2007) 1483-1487
14. Pfeifer D., Kist R., Dewar K., Devon K., Lander E.S., Birren B., et al. Campomelic dysplasia translocation breakpoints are scattered over 1 Mb proximal to SOX9: evidence for an extended control region. Am J Hum Genet 65 (1999) 111-124
15. Pfeifer D., Poulat F., Holinski-Feder E., Kooy F., and Scherer G. The SOX8 gene is located within 700 kb of the tip of chromosome 16p and is deleted in a patient with ATR-16 syndrome. Genomics 63 (2000) 108-116
16. Reiprich S., Stolt C.C., Schreiner S., Parlato R., and Wegner M. SoxE proteins are differentially required in mouse adrenal gland development. Mol Biol Cell 19 (2008) 1575-1586
17. Sandelin A., Bailey P., Bruce S., Engstrom P.G., Klos J.M., Wasserman W.W., et al. Arrays of ultraconserved non-coding regions span the loci of key developmental genes in vertebrate genomes. BMC Genomics 5 (2004) 99
18. Schepers G., Wilson M., Wilhelm D., and Koopman P. Sox8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the AMH promoter in vitro. J Biol Chem 278 (2003) 28101-28108
19. Schmidt K., Schinke T., Haberland M., Priemel M., Schilling A.F., Mueldner C., et al. The high-mobility-group transcription factor Sox8 is a negative regulator of osteoblast differentiation. J Cell Biol 168 (2005) 899-910
20. Sekido R., and Lovell-Badge R. Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer. Nature 453 (2008) 930-934
21. Sock E., Schmidt K., Hermanns-Borgmeyer I., Bösl M.R., and Wegner M. Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8. Mol Cell Biol 21 (2001) 6951-6959
22. Stolt C.C., Lommes P., Friedrich R.P., and Wegner M. Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development 131 (2004) 2349-2358
23. Thoss V.S., Perez J., Duc D., and Hoyer D. Embryonic and postnatal mRNA distribution og five somatostatin receptor subtypes in the rat brain. Neuropharmacology 34 (1995) 1673-1688
24. Werner T., Hammer A., Wahlbuhl M., Bösl M.R., and Wegner M. Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis. Nucleic Acids Res 35 (2007) 6526-6538
25. Woolfe A., Goodson M., Goode D.K., Snell P., McEwen G.K., Vavouri T., et al. Highly conserved non-coding sequences are associated with vertebrate development. PLoS Biol 3 (2005) e7
26. Wunderle V.M., Critcher R., Hastie N., Goodfellow P.N., and Schedl A. Deletion of longe-range regulatory elements upstream of SOX9 causes campomelic dysplasia. Proc Natl Acad Sci USA 95 (1998) 10646-10654