Model simplification procedure for signal transduction pathway models: An application to IL-6 signaling

Chemical Engineering Science

Volumn 65, Issue 6, 2010, Pages 1964-1975

 

^a Jacky) Huang, Zuyi   (United States)

Author keywords

Biomedical engineering; Cellular biology and engineering; Mathematical modeling; Model reduction; Signal Transduction; Systems engineering

Indexed keywords

CELLULAR BIOLOGY; CELLULAR BIOLOGY AND ENGINEERING; DEGREE OF OBSERVABILITY; DYNAMIC BEHAVIORS; EXPERIMENTAL DATA; HIGHLY-CORRELATED; IDENTIFIABILITY; INITIAL ESTIMATE; MATHEMATICAL MODELING; MODEL REDUCTION; MODEL SIMPLIFICATION; MODEL SIZE; NEW MODEL; ORIGINAL MODEL; PARAMETER IDENTIFIABILITY; PHYSICAL INTERPRETATION; POTENTIAL MEASUREMENTS; POTENTIAL SOLUTIONS; QUANTITATIVE DATA; REACTION PARAMETERS; SIGNAL TRANSDUCTION PATHWAYS; SIMPLIFIED MODELS; SIMULATION DATA; STATE VARIABLES; UNCERTAIN PARAMETERS;

BACTERIOPHAGES; BIOLOGY; BIOMEDICAL ENGINEERING; ENGINEERING; MODEL STRUCTURES; PROTEINS; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; SYSTEMS ENGINEERING; UNCERTAINTY ANALYSIS;

MATHEMATICAL MODELS;

EID: 76549111911     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2009.11.035     Document Type: Article

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