J-Wave Syndromes Caused by Repolarization or Depolarization Mechanisms. A Debated Issue Among Experimental and Clinical Electrophysiologists

Journal of the American College of Cardiology

Volumn 55, Issue 8, 2010, Pages 798-800

  Borggrefe, Martin ^a   Schimpf, Rainer ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

body surface potential mapping; Brugada syndrome; electrocardiography; sudden cardiac death; vectorcardiography

Indexed keywords

ANGINA PECTORIS; BRAIN INJURY; BRUGADA SYNDROME; CORONARY ARTERY CIRCUMFLEX BRANCH; EDITORIAL; ELECTROCARDIOGRAPHY; GENOTYPE; HEART ATRIUM FIBRILLATION; HEART DEPOLARIZATION; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART REPOLARIZATION; HEART VENTRICLE TACHYCARDIA; HYPERCALCEMIA; HYPOTHERMIA; POTASSIUM CURRENT; PRIORITY JOURNAL; QRS COMPLEX; ST SEGMENT; ST SEGMENT ELEVATION; T WAVE;

BRUGADA SYNDROME; CARDIAC ELECTROPHYSIOLOGY; ELECTROCARDIOGRAPHY; HUMANS;

EID: 76449091667     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2009.12.006     Document Type: Editorial

References (21)

1. Osborn J.J. Experimental hypothermia; respiratory and blood pH changes in relation to cardiac function. Am J Physiol 175 (1953) 389-398
2. Brugada P., and Brugada J. Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 20 (1992) 1391-1396
3. Antzelevitch C., Brugada P., Borggrefe M., et al. Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association. Circulation 111 (2005) 659-670
4. Wilde A.A., Antzelevitch C., Borggrefe M., et al. Proposed diagnostic criteria for the Brugada syndrome. Eur Heart J 23 (2002) 1648-1654
5. Postema P.G., van Dessel P.F.H.M., Kors J.A., et al. Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in Brugada syndrome. a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation. J Am Coll Cardiol 55 (2010) 789-797
6. Antzelevitch C., and Yan G.X. Cellular and ionic mechanisms responsible for the Brugada syndrome. J Electrocardiol 33 Suppl (2000) 33-39
7. Yan G.X., and Antzelevitch C. Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation. Circulation 100 (1999) 1660-1666
8. Papavassiliu T., Wolpert C., Fluchter S., et al. Magnetic resonance imaging findings in patients with Brugada syndrome. J Cardiovasc Electrophysiol 15 (2004) 1133-1138
9. Antzelevitch C. Cellular basis and mechanism underlying normal and abnormal myocardial repolarization and arrhythmogenesis. Ann Med 36 Suppl 1 (2004) 5-14
10. Antzelevitch C. Modulation of transmural repolarization. Ann N Y Acad Sci 1047 (2005) 314-3
11. Antzelevitch C., Shimizu W., Yan G.X., et al. The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart. J Cardiovasc Electrophysiol 10 (1999) 1124-1152
12. Yan G.X., and Antzelevitch C. Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome. Circulation 98 (1998) 1928-1936
13. Yan G.X., and Antzelevitch C. Cellular basis for the electrocardiographic J wave. Circulation 93 (1996) 372-379
14. Antzelevitch C., and Sicouri S. Clinical relevance of cardiac arrhythmias generated by afterdepolarizations. Role of M cells in the generation of U waves, triggered activity and torsade de pointes. J Am Coll Cardiol 23 (1994) 259-277
15. Bloch Thomsen P.E., Joergensen R.M., Kanters J.K., et al. Phase 2 reentry in man. Heart Rhythm 2 (2005) 797-803
16. Smits J.P., Eckardt L., Probst V., et al. Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients. J Am Coll Cardiol 40 (2002) 350-356
17. Frustaci A., Priori S.G., Pieroni M., et al. Cardiac histological substrate in patients with clinical phenotype of Brugada syndrome. Circulation 112 (2005) 3680-3687
18. Lambiase P.D., Ahmed A.K., Ciaccio E.J., et al. High-density substrate mapping in Brugada syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis. Circulation 120 (2009) 106-117 1-4
19. Nagase S., Kusano K.F., Morita H., et al. Epicardial electrogram of the right ventricular outflow tract in patients with the Brugada syndrome: using the epicardial lead. J Am Coll Cardiol 39 (2002) 1992-1995
20. Masaki R., Watanabe I., Nakai T., et al. Role of signal-averaged electrocardiograms for predicting the inducibility of ventricular fibrillation in the syndrome consisting of right bundle branch block and ST segment elevation in leads V1-V3. Jpn Heart J 43 (2002) 367-378
21. Morita H., Kusano K.F., Miura D., et al. Fragmented QRS as a marker of conduction abnormality and a predictor of prognosis of Brugada syndrome. Circulation 118 (2008) 1697-1704