The impact of viruses in lower respiratory tract infections of the adult;Die Rolle von Viren bei tiefen Atemwegsinfektionen des Erwachsenen

Pneumologie

Volumn 64, Issue 1, 2010, Pages 18-27

  Ott, S R ^a,b   Rohde, G ^c   Lepper, P M ^b   Hauptmeier, B ^c   Bals, R ^d   Pletz, M W R ^e   Schumann, C ^f   Steininger, C ^g   Kleines, M ^h   Geerdes Fenge, H ⁱ  

^a HELIOS KLINIKUM EMIL VON BEHRING   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

^c RUHR UNIVERSITY BOCHUM   (Germany)

^d UNIVERSITY HOSPITAL GIESSEN   (Germany)

^e HANNOVER MEDICAL SCHOOL   (Germany)

^f UNIVERSITY HOSPITAL ULM   (Germany)

^g MEDICAL UNIVERSITY OF VIENNA   (Austria)

^h UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

ⁱ Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit München   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; OSELTAMIVIR; PLACEBO; ZANAMIVIR;

BRONCHITIS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL FEATURE; CLINICAL TRIAL; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE EXACERBATION; HOSPITAL INFECTION; HUMAN; INFLUENZA; LOWER RESPIRATORY TRACT INFECTION; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; PREVENTION; PRIORITY JOURNAL; RESPIRATORY VIRUS; REVIEW; TRACHEOBRONCHITIS; VIRUS VIRULENCE;

BRONCHITIS; DIAGNOSIS, DIFFERENTIAL; HUMANS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY TRACT INFECTIONS; VIRUS DISEASES;

EID: 76249115405     PISSN: 09348387     EISSN: 14388790     Source Type: Journal    
DOI: 10.1055/s-0029-1215197     Document Type: Review

References (108)

1. Holmes W F., Macfarlane J T., Macfarlane R M., et al. Symptoms, signs, and prescribing for acute lower respiratory tract illness. Br J Gen Pract 2001 51 177-181
2. Gonzales R, Sande M A. Uncomplicated acute bronchitis. Ann Intern Med 2000 133 981-991
3. Braman S S. Chronic cough due to acute bronchitis: ACCP evidence-based clinical practice guidelines. Chest 2006 129 (Suppl 1) 95S-103S
4. Thiadens H A., Postma D S., de Bock G H., et al. Asthma in adult patients presenting with symptoms of acute bronchitis in general practice. Scand J Prim Health Care 2000 18 188-192
5. Höffken G, Lorenz J, Kern W, et al. S3-Leitlinie zur Epidemiologie, Diagnostik, antimikrobieller Therapie und Management von erwachsenen Patienten mit ambulant erworbenen tiefen Atemwegsinfektionen (akute Bronchitis, akute Exazerbation einer chronischen Bronchitis, Influenza und andere respiratorische Virusinfektionen) sowie ambulant erworbene Pneumonie. Pneumologie 2005 59 612-664
6. Techniker Krankenkasse. Gesundheitsreport 2006. 2006
7. Cate T R., Couch R B., Fleet W F., et al. Production of Tracheobronchitis in Volunteers with Rhinovirus in a Small-Particle Aerosol. Am J Epidemiol 1965 81 95-105
8. Jonsson J S., Sigurdsson J A., Kristinsson K G., et al. Acute bronchitis in adults. How close do we come to its aetiology in general practice? Scand J Prim Health Care 1997 15 156-160
9. Boldy D A., Skidmore S J., Ayres J G. Acute bronchitis in the community: clinical features, infective factors, changes in pulmonary function and bronchial reactivity to histamine. Respir Med 1990 84 377-385
10. Macfarlane J, Holmes W, Gard P, et al. Prospective study of the incidence, aetiology and outcome of adult lower respiratory tract illness in the community. Thorax 2001 56 109-114
11. Freymuth F, Vabret A, Gouarin S, et al. Epidemiology and diagnosis of respiratory syncytial virus in adults. Rev Mal Respir 2004 21 35-42
12. Nicholson K G., Kent J, Hammersley V, et al. Risk factors for lower respiratory complications of rhinovirus infections in elderly people living in the community: prospective cohort study. BMJ 1996 313 1119-1123
13. Smucny J, Fahey T, Becker L, et al. Antibiotics for acute bronchitis. Cochrane Database Syst Rev 2004 4 CD000245
14. Evans A T., Husain S, Durairaj L, et al. Azithromycin for acute bronchitis: a randomised, double-blind, controlled trial. Lancet 2002 359 1648-1654
15. Van den Hoogen B G., Osterhaus D M., Fouchier R A. Clinical impact and diagnosis of human metapneumovirus infection. Pediatr Infect Dis J 2004 23 (Suppl 1) 25-32
16. Prins J M., Wolthers K C. Human metapneumovirus: a new pathogen in children and adults. Neth J Med 2004 62 177-179
17. Kaye M, Skidmore S, Osman H, et al. Surveillance of respiratory virus infections in adult hospital admissions using rapid methods. Epidemiol Infect 2006 134 792-798
18. Vabret A, Mourez T, Gouarin S, et al. An outbreak of coronavirus OC43 respiratory infection in Normandy, France. Clin Infect Dis 2003 36 985-989
19. Knutson D, Braun C. Diagnosis and management of acute bronchitis. Am Fam Physician 2002 65 2039-2044
20. Kardos P, Cegla U, Gillissen A, et al. Leitlinie der Deutschen Gesellschaft für Pneumologie zur Diagnostik und Therapie von Patienten mit akutem und chronischem Husten. Pneumologie 2004 58 570-602 (Pubitemid 39144409)
21. Melbye H, Kongerud J, Vorland L. Reversible airflow limitation in adults with respiratory infection. Eur Respir J 1994 7 1239-1245
22. Macfarlane J, Holmes W, Gard P, et al. Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. BMJ 2002 324 91-94
23. Rabe K F., Beghe B, Luppi F, et al. Update in chronic obstructive pulmonary disease 2006. Am J Respir Crit Care Med 2007 175 1222-1232
24. Seemungal T A., Donaldson G C., Paul E A., et al. Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1998 157 1418-1422
25. Burge S, Wedzicha J A. COPD exacerbations: definitions and classifications. Eur Respir J Suppl 2003 41 46s-53s
26. Rodriguez-Roisin R. Toward a consensus definition for COPD exacerbations. Chest 2000 117 (Suppl 2) 398S-401S
27. Anthonisen N R., Manfreda J, Warren C P., et al. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med 1987 106 196-204
28. WHO. World Health Report 2008. 2008
29. Connors A F., Dawson N V., Thomas C, et al. Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments). Am J Respir Crit Care Med 1996 154 959-967
30. Groenewegen K H., Schols A M., Wouters E F. Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD. Chest 2003 124 459-467
31. Kanner R E., Anthonisen N R., Connett J E. Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study. Am J Respir Crit Care Med 2001 164 358-364
32. Donaldson G C., Seemungal T A., Bhowmik A, et al. Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002 57 847-852
33. Murphy T F., Sethi S, Niederman M. The role of bacteria in exacerbations of COPD. A constructive view. Chest 2000 118 204-209
34. Greenberg S B., Allen M, Wilson J, et al. Respiratory viral infections in adults with and without chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000 162 167-173
35. Bandi V, Apicella M A., Mason E, et al. Nontypeable Haemophilus influenzae in the lower respiratory tract of patients with chronic bronchitis. Am J Respir Crit Care Med 2001 164 2114-2119
36. Patel I S., Seemungal T A., Wilks, et al. Relationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbations. Thorax 2002 57 759-764
37. Saint S, Bent S, Vittinghoff E, et al. Antibiotics in chronic obstructive pulmonary disease exacerbations. A meta-analysis. Jama 1995 273 957-960
38. MacNee W, Calverley S M. Chronic obstructive pulmonary disease. 7: Management of COPD. Thorax 2003 58 261-265
39. Wedzicha J A. Role of viruses in exacerbations of chronic obstructive pulmonary disease. Proc Am Thorac Soc 2004 1 115-120
40. Seemungal T, Harper-Owen R, Bhowmik A, et al. Respiratory viruses, symptoms, and inflammatory markers in acute exacerbations and stable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2001 164 1618-1623
41. Seemungal T A., Donaldson G C., Bhowmik A, et al. Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2000 161 1608-1613
42. Tan W C., Xiang X, Qui D, et al. Epidemiology of respiratory viruses in patients hospitalized with near-fatal asthma, acute exacerbations of asthma, or chronic obstructive pulmonary disease. Am J Med 2003 115 272-277
43. Rohde G, Wiethege A, Borg I, et al. Respiratory viruses in exacerbations of chronic obstructive pulmonary disease requiring hospitalisation: a case-control study. Thorax 2003 58 37-42
44. Papi A, Bellettato C M., Braccioni F, et al. Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations. Am J Respir Crit Care Med 2006 173 1114-1121 (Pubitemid 43726892)
45. Wilkinson T M., Hurst J R., Perera W R., et al. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD. Chest 2006 129 317-324
46. Barnes P J. Chronic obstructive pulmonary disease. N Engl J Med 2000 343 269-280
47. Rohde G, Borg I, Wiethege A, et al. Inflammatory response in acute viral exacerbations of COPD. Infection 2008 36 427-433
48. Hogg J C., Chu F, Utokaparch S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004 350 2645-2653
49. Rohde G, Schlosser B, Arinir U, et al. The role of respiratory infections in chronic obstructive pulmonary disease. Med Klin (München) 2007 102 893-898
50. Borg I, Rohde G, Loseke S, et al. Evaluation of a quantitative real-time PCR for the detection of respiratory syncytial virus in pulmonary diseases. Eur Respir J 2003 21 944-951
51. Rohde G, Wiethege A, Borg I, et al. Influenza A virus in Exacerbation of chronic obstruktive pulmonary disease. Eur Respir J Suppl 2001 18 (Suppl 33) 152
52. Worth H, Buhl R, Cegla U, et al. Leitlinie der Deutschen Atemwegsliga und der Deutschen Gesellschaft für Pneumologie zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD). Pneumologie 2002 56 704-738
53. Ruiz M, Ewig S, Marcos M A., et al. Etiology of community-acquired pneumonia: impact of age, comorbidity, and severity. Am J Respir Crit Care Med 1999 160 397-405
54. Lim W S., Macfarlane J T., Boswell T C., et al. Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines. Thorax 2001 56 296-301
55. Welte T, Kohnlein T. Global and local epidemiology of community-acquired pneumonia: the experience of the CAPNETZ Network. Semin Respir Crit Care Med 2009 30 127-135
56. Fang G D., Fine M, Orloff J, et al. New and emerging etiologies for community-acquired pneumonia with implications for therapy. A prospective multicenter study of 359 cases. Medicine (Baltimore) 1990 69 307-316
57. Dowell S F., Anderson L J., Gary H E. Jr., et al. Respiratory syncytial virus is an important cause of community-acquired lower respiratory infection among hospitalized adults. J Infect Dis 1996 174 456-462
58. Almirall J, Bolibar I, Vidal J, et al. Epidemiology of community-acquired pneumonia in adults: a population-based study. Eur Respir J 2000 15 757-763
59. Woodhead M. Community-acquired pneumonia guidelines an international comparison: a view from Europe. Chest 1998 113 (Suppl) 183S-187S
60. De Roux A, Marcos M A., Garcia E, et al. Viral community-acquired pneumonia in nonimmunocompromised adults. Chest 2004 125 1343-1351
61. Angeles Marcos M, Camps M, Pumarola T, et al. The role of viruses in the aetiology of community-acquired pneumonia in adults. Antivir Ther 2006 11 351-359
62. Ewig S. Community-acquired pneumonia: definition, epidemiology, and outcome. Semin Respir Infect 1999 14 94-102 (Pubitemid 29269987)
63. Krech T, Wegmann T, Martin H, et al. Etiology of atypical pneumonias. A serological study on 1494 patients. Schweiz Med Wochenschr 1986 116 2-7
64. Farr B M., Kaiser D L., Harrison B D., et al. Prediction of microbial aetiology at admission to hospital for pneumonia from the presenting clinical features. British Thoracic Society Pneumonia Research Subcommittee. Thorax 1989 44 1031-1035
65. Dahmash N S., Chowdhury M N. Re-evaluation of pneumonia requiring admission to an intensive care unit: a prospective study. Thorax 1994 49 71-76
66. Bohte R, van Furth R, van den Broek P F. Aetiology of community-acquired pneumonia: a prospective study among adults requiring admission to hospital. Thorax 1995 50 543-547
67. Socan M, Marinic-Fiser N, Kraigher A, et al. Microbial aetiology of community-acquired pneumonia in hospitalised patients. Eur J Clin Microbiol Infect Dis 1999 18 777-782
68. Hamelin M E., Cote S, Laforge J, et al. Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease. Clin Infect Dis 2005 41 498-502
69. La Scola B, Marrie T J., Auffray J P., et al. Mimivirus in pneumonia patients. Emerg Infect Dis 2005 11 449-452
70. Johnstone J, Majumdar S R., Fox J D., et al. Human metapneumovirus pneumonia in adults: results of a prospective study. Clin Infect Dis 2008 46 571-574
71. Cebular S, Lee S, Tolaney P, et al. Community-acquired pneumonia in immunocompromised patients. Opportunistic infections to consider in differential diagnosis. Postgrad Med 2003 113 65-66, 6970, 7374
72. Duffau P, Moiton M P., Lafon M E., et al. A case of severe community acquired pneumonia and non-respiratory illness induced by Influenza A. Med Mal Infect 2006 36 473-475
73. Lee D G., Yoo J H., Choi J H., et al. A fatal case of measles pneumonia complicating an adult recipient of hemopoietic stem cell transplantation during the nationwide epidemic in Korea. Int J Infect Dis 2006 10 410-411
74. Kobashi Y, Okimoto N, Matsushima T, et al. Clinical analysis of community-acquired pneumonia in the elderly. Intern Med 2001 40 703-707 (Pubitemid 32799414)
75. Gutierrez F, Masia M, Mirete C, et al. The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens. J Infect 2006 53 166-174
76. Johnstone J, Majumdar S R., Fox J D., et al. Viral infection in adults hospitalized with community-acquired pneumonia: prevalence, pathogens, and presentation. Chest 2008 134 1141-1148
77. Jennings L C., Anderson T P., Beynon K A., et al. Incidence and characteristics of viral community-acquired pneumonia in adults. Thorax 2008 63 42-48
78. Ruiz-Gonzalez A, Falguera M, Nogues A, et al. Is Streptococcus pneumoniae the leading cause of pneumonia of unknown etiology? A microbiologic study of lung aspirates in consecutive patients with community-acquired pneumonia. Am J Med 1999 106 385-390
79. Ishida T, Hasimoto T, Arita M, et al. Efficacy of transthoracic needle aspiration in community-acquired pneumonia. Intern Med 2001 40 873-877
80. Nseir S, Di Pompeo C, Pronnier P, et al. Nosocomial tracheobronchitis in mechanically ventilated patients: incidence, aetiology and outcome. Eur Respir J 2002 20 1483-1489
81. ATS/IDSA. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005 171 388-416
82. Louie M, Dyck B, Parker S, et al. Nosocomial pneumonia in a Canadian tertiary care center: a prospective surveillance study. Infect Control Hosp Epidemiol 1991 12 356-363
83. Daubin C, Parienti J J., Vincent S, et al. Epidemiology and clinical outcome of virus-positive respiratory samples in ventilated patients: a prospective cohort study. Crit Care 2006 10 R142
84. Ong G M., Lowry K, Mahajan S, et al. Herpes simplex type 1 shedding is associated with reduced hospital survival in patients receiving assisted ventilation in a tertiary referral intensive care unit. J Med Virol 2004 72 121-125
85. Camps K, Jorens P G., Demey H E., et al. Clinical significance of herpes simplex virus in the lower respiratory tract of critically ill patients. Eur J Clin Microbiol Infect Dis 2002 21 758-759
86. De Vos N, Van Hoovels L, Vankeerberghen A, et al. Monitoring of herpes simplex virus in the lower respiratory tract of critically ill patients using real-time PCR: a prospective study. Clin Microbiol Infect 2009 15 358-363
87. Daubin C, Vincent S, Vabret A, et al. Nosocomial viral ventilator-associated pneumonia in the intensive care unit: a prospective cohort study. Intensive Care Med 2005 31 1116-1122
88. Porteous C, Bradley J A., Hamilton D N., et al. Herpes simplex virus reactivation in surgical patients. Crit Care Med 1984 12 626-628
89. Hanley P J., Conaway M M., Halstead D C., et al. Nosocomial herpes simplex virus infection associated with oral endotracheal intubation. Am J Infect Control 199 21 310-316
90. Byers R J., Hasleton P S., Quigley A, et al. Pulmonary herpes simplex in burns patients. Eur Respir J 1996 9 2313-2317
91. Bruynseels P, Jorens P G., Demey H E., et al. Herpes simplex virus in the respiratory tract of critical care patients: a prospective study. Lancet 2003 362 1536-1541
92. Luyt C E., Combea A, Deback C, et al. Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation. Am J Respir Crit Care Med 2007 175 935-942
93. Schuller D, Spessert C, Fraser V J., et al. Herpes simplex virus from respiratory tract secretions: epidemiology, clinical characteristics, and outcome in immunocompromised and nonimmunocompromised hosts. Am J Med 1993 94 29-33
94. Engelmann I, Gottlieb J, Meier A, et al. Clinical relevance of and risk factors for HSV-related tracheobronchitis or pneumonia: results of an outbreak investigation. Crit Care 2007 11 R119
95. Tuxen D V., Wilson J W., Cade J F. Prevention of lower respiratory herpes simplex virus infection with acyclovir in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 1987 136 402-405
96. Van den Brink J W., Simoons-Smit A M., Beihuizen A, et al. Respiratory herpes simplex virus type 1 infection/colonisation in the critically ill: marker or mediator? J Clin Virol 2004 30 68-72
97. Ziemann M, Sedemund-Adib B, Reiland P, et al. Increased mortality in long-term intensive care patients with active cytomegalovirus infection. Crit Care Med 2008 36 3145-3150
98. Heininger A, Jahn G, Engel C, et al. Human cytomegalovirus infections in nonimmunosuppressed critically ill patients. Crit Care Med 2001 29 541-547
99. Jaber S, Chanques G, Borry J, et al. Cytomegalovirus infection in critically ill patients: associated factors and consequences. Chest 2005 127 233-241
100. Guidry G G., Black-Payne C A., Payne D K., et al. Respiratory syncytial virus infection among intubated adults in a university medical intensive care unit. Chest 1991 100 1377-1384
101. Oliveira E C., Lee B, Colice G L. Influenza in the intensive care unit. J Intensive Care Med 2003 18 80-91
102. Malcolm E, Arruda E, Hayden F G., et al. Clinical features of patients with acute respiratory illness and rhinovirus in their bronchoalveolar lavages. J Clin Virol 2001 21 9-16
103. Stollenwerk N, Harper R W., Sandrock C E. Bench-to-bedside review: rare and common viral infections in the intensive care unit linking pathophysiology to clinical presentation. Crit Care 2008 12 219
104. Tellier R. Review of aerosol transmission of influenza A virus. Emerg Infect Dis 2006 12 1657-1662
105. Brundage J F. Cases and deaths during influenza pandemics in the United States. Am J Prev Med 2006 31 252-256
106. Jamieson D J., Honein M A., Rasmussen S A., et al. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet 2009 374 451-458
107. Boivin G, Hardy I, Tellier G, et al. Predicting influenza infections during epidemics with use of a clinical case definition. Clin Infect Dis 2000 31 1166-1169
108. Lieberman D, Schlaeffer F, Boldur I, et al. Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients. Thorax 1996 51 179-184