메뉴 건너뛰기




Volumn 127, Issue 3, 2010, Pages 771-776

Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism

Author keywords

AMPK; Diabetes; Ginsenoside Rc; Glucose uptake; Insulin signal

Indexed keywords

GINSENOSIDE RC; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

EID: 76149144996     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.11.022     Document Type: Article
Times cited : (75)

References (30)
  • 1
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional Report of a WHO Consultation
    • Alberti K.G., Zimmet P.Z. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional Report of a WHO Consultation. Diabetic Medicine 1998, 15:539-553.
    • (1998) Diabetic Medicine , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 2
    • 33947495248 scopus 로고    scopus 로고
    • Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance
    • Canova M., Vavrinkova H., Kazdova L. Glucose-fatty acid interaction in skeletal muscle and adipose tissue in insulin resistance. Physiological Research 2007, 56:1-15.
    • (2007) Physiological Research , vol.56 , pp. 1-15
    • Canova, M.1    Vavrinkova, H.2    Kazdova, L.3
  • 3
    • 4444335894 scopus 로고    scopus 로고
    • Embryotoxicity study of ginsenoside Rc and Re in in vitro rat whole embryo culture
    • Chan L.Y., Chiu P.Y., Lau T.K. Embryotoxicity study of ginsenoside Rc and Re in in vitro rat whole embryo culture. Reproductive Toxicology 2004, 19:131-134.
    • (2004) Reproductive Toxicology , vol.19 , pp. 131-134
    • Chan, L.Y.1    Chiu, P.Y.2    Lau, T.K.3
  • 5
    • 20944436176 scopus 로고    scopus 로고
    • Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus
    • Fadini G.P., Miorin M., Facco M., Bonamico S. Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. Journal of American College of Cardiology 2005, 45:1449-1457.
    • (2005) Journal of American College of Cardiology , vol.45 , pp. 1449-1457
    • Fadini, G.P.1    Miorin, M.2    Facco, M.3    Bonamico, S.4
  • 7
    • 33751183316 scopus 로고    scopus 로고
    • Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca2+-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells
    • Ham Y.M., Lim J.H., Na H.K., Choi J.S., Park B.D., Yim H., Lee S.K. Ginsenoside-Rh2-induced mitochondrial depolarization and apoptosis are associated with reactive oxygen species- and Ca2+-mediated c-Jun NH2-terminal kinase 1 activation in HeLa cells. Journal of Pharmacology and Experimental Therapeutics 2006, 319:1276-1285.
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.319 , pp. 1276-1285
    • Ham, Y.M.1    Lim, J.H.2    Na, H.K.3    Choi, J.S.4    Park, B.D.5    Yim, H.6    Lee, S.K.7
  • 10
    • 60549098274 scopus 로고    scopus 로고
    • Obesity and diabetes: lipids, 'nowhere to run to'
    • Hill M.J., Metcalfe D., McTernan P.G. Obesity and diabetes: lipids, 'nowhere to run to'. Clinical Science 2009, 116:113-123.
    • (2009) Clinical Science , vol.116 , pp. 113-123
    • Hill, M.J.1    Metcalfe, D.2    McTernan, P.G.3
  • 13
    • 32444437879 scopus 로고    scopus 로고
    • Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice
    • Ito Y., Obara K., Ikeda R., Ishii M., Tanabe Y., Ishikawa T., Nakayama K. Passive stretching produces Akt- and MAPK-dependent augmentations of GLUT4 translocation and glucose uptake in skeletal muscles of mice. Pflugers Archive 2006, 451:803-813.
    • (2006) Pflugers Archive , vol.451 , pp. 803-813
    • Ito, Y.1    Obara, K.2    Ikeda, R.3    Ishii, M.4    Tanabe, Y.5    Ishikawa, T.6    Nakayama, K.7
  • 14
    • 34547872783 scopus 로고    scopus 로고
    • Inhibition of p38 MAPK and AMPK restores adenosine-induced cardioprotection in hearts stressed by antecedent ischemia by altering glucose utilization
    • Jaswal J.S., Gandhi M., Finegan B.A., Dyck J.R., Clanachan A.S. Inhibition of p38 MAPK and AMPK restores adenosine-induced cardioprotection in hearts stressed by antecedent ischemia by altering glucose utilization. American Journal of Physiology Heart and Circulatory Physiology 2007, 293:1107-1114.
    • (2007) American Journal of Physiology Heart and Circulatory Physiology , vol.293 , pp. 1107-1114
    • Jaswal, J.S.1    Gandhi, M.2    Finegan, B.A.3    Dyck, J.R.4    Clanachan, A.S.5
  • 16
    • 47349090618 scopus 로고    scopus 로고
    • Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells
    • Juan M.E., Wenzel U., Daniel H., Planas J.M. Resveratrol induces apoptosis through ROS-dependent mitochondria pathway in HT-29 human colorectal carcinoma cells. Journal of Agricultural Food Chemistry 2008, 56:4813-4818.
    • (2008) Journal of Agricultural Food Chemistry , vol.56 , pp. 4813-4818
    • Juan, M.E.1    Wenzel, U.2    Daniel, H.3    Planas, J.M.4
  • 17
    • 64549086074 scopus 로고    scopus 로고
    • Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells
    • Kim D.Y., Yuan H.D., Chung I.K., Chung S.H. Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells. Journal of Agricultural Food Chemistry 2009, 57:1532-1537.
    • (2009) Journal of Agricultural Food Chemistry , vol.57 , pp. 1532-1537
    • Kim, D.Y.1    Yuan, H.D.2    Chung, I.K.3    Chung, S.H.4
  • 21
    • 57749093010 scopus 로고    scopus 로고
    • Retinoic acid leads to cytoskeletal rearrangement through AMPK-Rac1 and stimulates glucose uptake through AMPK-p38 MAPK in skeletal muscle cells
    • Lee Y.M., Lee J.O., Jung J.H., Kim J.H., Park S.H., Park J.M., Kim E.K., Suh P.G., Kim H.S. Retinoic acid leads to cytoskeletal rearrangement through AMPK-Rac1 and stimulates glucose uptake through AMPK-p38 MAPK in skeletal muscle cells. Journal of Biological Chemistry 2008, 283:33969-33974.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 33969-33974
    • Lee, Y.M.1    Lee, J.O.2    Jung, J.H.3    Kim, J.H.4    Park, S.H.5    Park, J.M.6    Kim, E.K.7    Suh, P.G.8    Kim, H.S.9
  • 23
    • 62549115284 scopus 로고    scopus 로고
    • Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats
    • Palsamy P., Subramanian S. Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats. Chemico Biological Interaction 2009, 79:356-362.
    • (2009) Chemico Biological Interaction , vol.79 , pp. 356-362
    • Palsamy, P.1    Subramanian, S.2
  • 24
    • 48849084718 scopus 로고    scopus 로고
    • Pyrogallol inhibits the growth of gastric cancer SNU-484 cells via induction of apoptosis
    • Park W.H., Park M.N., Han Y.H., Kim S.W. Pyrogallol inhibits the growth of gastric cancer SNU-484 cells via induction of apoptosis. International Journal of Molecular Medicine 2008, 22:263-268.
    • (2008) International Journal of Molecular Medicine , vol.22 , pp. 263-268
    • Park, W.H.1    Park, M.N.2    Han, Y.H.3    Kim, S.W.4
  • 25
    • 17744363472 scopus 로고    scopus 로고
    • Adenosine 5′-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes
    • Pelletier A., Joly E., Prentki M., Coderre L. Adenosine 5′-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes. Endocrinology 2005, 146:2285-2294.
    • (2005) Endocrinology , vol.146 , pp. 2285-2294
    • Pelletier, A.1    Joly, E.2    Prentki, M.3    Coderre, L.4
  • 27
    • 23944459079 scopus 로고    scopus 로고
    • Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease
    • Smith A.G., Muscat G.E. Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease. International Journal of Biochemistry and Cell Biology 2005, 37:2047-2056.
    • (2005) International Journal of Biochemistry and Cell Biology , vol.37 , pp. 2047-2056
    • Smith, A.G.1    Muscat, G.E.2
  • 28
    • 63049115868 scopus 로고    scopus 로고
    • Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans
    • Solomon T.P., Blannin A.K. Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. European Journal of Applied Physiology 2009, 105:969-976.
    • (2009) European Journal of Applied Physiology , vol.105 , pp. 969-976
    • Solomon, T.P.1    Blannin, A.K.2
  • 30


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.