Reduced IFN-γ- and enhanced IL-4-producing CD4 + cord blood T cells are associated with a higher risk for atopic dermatitis during the first 2 yr of life

Pediatric Allergy and Immunology

Volumn 21, Issue 1 PART I, 2010, Pages 5-13

  Herberth, Gunda ^a   Heinrich, Joachim ^b   Röder, Stefan ^a   Figl, Adina ^a,c   Weiss, Michael ^d   Diez, Ulrike ^a,e   Borte, Michael ^c,e   Herbarth, Olf ^a,c   Lehmann, Irina ^a  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c UNIVERSITY OF LEIPZIG   (Germany)

^d Children's Hospital   (Germany)

^e Klinikum St Georg   (Germany)

Author keywords

Atopic dermatitis; Cord blood; Infancy; Interferon ; Interleukin 4; Neonates; T cells; T helper 1; T helper 2

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; TOBACCO SMOKE;

ALLERGIC ASTHMA; ALLERGIC RHINITIS; ARTICLE; ATOPIC DERMATITIS; ATOPY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHILD; CYTOKINE PRODUCTION; EDUCATIONAL STATUS; ENVIRONMENTAL EXPOSURE; FAMILY HISTORY; FEMALE; GERMANY; HIGH RISK POPULATION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MATERNAL SMOKING; OUTCOME ASSESSMENT; PARENT; PET ANIMAL; PREGNANCY; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; TH1 CELL; TH2 CELL; UMBILICAL CORD BLOOD;

ADULT; CD4-POSITIVE T-LYMPHOCYTES; CHILD, PRESCHOOL; COHORT STUDIES; CYTOKINES; DERMATITIS, ATOPIC; FEMALE; FETAL BLOOD; HUMANS; INFANT; INFANT, NEWBORN; INTERFERON-GAMMA; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MALE; PREGNANCY; RISK FACTORS; TH1 CELLS; TH2 CELLS; TIME FACTORS;

EID: 76149138494     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2009.00890.x     Document Type: Article

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