The influence of maternal exposure to volatile organic compounds on the cytokine secretion profile of neonatal T cells

Environmental Toxicology

Volumn 17, Issue 3, 2002, Pages 203-210

  Lehmann, I ^a   Thoelke, A ^a   Rehwagen, M ^a   Rolle Kampczyk, U ^a   Schlink, U ^a   Schulz, R ^a   Borte, M ^a   Diez, U ^a   Herbarth, O ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cytokines; Epidemiology; Interferon ; Interleukin 4; Naphthalene; Newborn children; Pregnancy; T cells; Tetrachlorethylenne; VOC

Indexed keywords

ALLERGIES; CELLS; FETAL MONITORING; IMMUNOLOGY; INDOOR AIR POLLUTION; VOLATILE ORGANIC COMPOUNDS;

MATERNAL EXPOSURE;

TOXICITY;

CYCLOPENTANE DERIVATIVE; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; NAPHTHALENE; TETRACHLOROETHYLENE; VOLATILE ORGANIC COMPOUND;

VOLATILE ORGANIC COMPOUND;

ARTICLE; CELL TYPE; CHILDBIRTH; CIGARETTE SMOKING; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENVIRONMENTAL EXPOSURE; FEMALE; HOME; HUMAN; IMMUNE STATUS; INDOOR AIR POLLUTION; LOGISTIC REGRESSION ANALYSIS; MALE; NEWBORN; PREGNANCY; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZATION; RISK ASSESSMENT; SAMPLING; T LYMPHOCYTE; UMBILICAL CORD BLOOD;

ADULT; AIR POLLUTION, INDOOR; CARCINOGENS; COHORT STUDIES; CYTOKINES; FEMALE; HUMANS; HYPERSENSITIVITY; INFANT, NEWBORN; MATERNAL EXPOSURE; NAPHTHALENES; ODDS RATIO; PREGNANCY; REGRESSION ANALYSIS; T-LYMPHOCYTES; TETRACHLOROETHYLENE; VOLATILIZATION;

EID: 0036062228     PISSN: 15204081     EISSN: None     Source Type: Journal    
DOI: 10.1002/tox.10055     Document Type: Article

References (36)

1. Measurement of volatile organic compounds in human blood
2. Do parental smoking and history of allergy influence cord-serum IgE?
3. Differences between IL-4R alpha-deficient and IL-4 deficient mice reveal a role for IL-13 in the regulation of Th2 responses
4. The environmental pollutant pyrene induces the production of IL-4
5. Indoor air pollutants. A literature review
6. Role and modulation of T-cell cytokines in allergy
7. Einfluss von Innenraumchemikalien auf die Häufigkeit von Infektionen der oberen Luftwege und die Atopie-Entwicklung in den ersten Lebenswochen
8. Effects of indoor painting and smoking on airway symptoms in atopy risk children in the first year of life results of the LARS-study
9. Trichloroacetic acid accumulates in murine amniotic fluid after tri- and tetrachloroethylene inhalation
10. VOCs-investigation into outdoor and indoor exposure: Initial results
11. Effect of indoor chemical exposure on the development of allergies in newborns-LARS study
12. Prenatal sensitization in a mouse model
13. Genetic "risk" for atopy is associated with delayed postnatal maturation of T-cell competence
14. Immune tolerance and protection against allergic sensitization
15. Enhanced in vivo IgE production and T cell polarization to the type 2 phenotype in association with indoor exposure to VOC: Results of the LARS study
16. T cell reactivity in neonates from an East and a West German city-Results of the LISA study
17. Endometrial Th2 cytokine expression throughout the menstrual cycle and early pregnancy
18. Effect of pre- and postnatal tobacco smoke exposure on specific sensitization to food and inhalant allergens during the first 3 years of life
19. Maternal smoking influences cord serum IgE and IgD levels and increases the risk for subsequent infant allergy
20. Regulation of fetal allograft survival by a hormone-controlled Th1- and Th2-type cytokines
21. Transplacental priming of the human immune system to environmental allergens: Universal skewing of initial T cell responses toward the Th2 cytokine profile
22. Interferon-gamma production by cord-blood mononuclear cells is reduced in newborns with a family history of atopic disease and is independent from cord blood IgE-levels
23. Th1-type immunity is incompatible with successful pregnancy
24. Role of interleukin 4 and gamma interferon in the regulation of human IgE synthesis: Possible alterations in atopic patients
25. Regulation of the development of type 2 T-helper cells in allergy
26. Health effects and sources of indoor air pollution
27. Health effects and sources of indoor air pollution
28. Interferon-gamma and B cell stimulatory factor reciprocally regulate Ig isotype production
29. Transplacental priming of the human immune system with environmental allergens can occur early in gestation
30. Reduced interferon-gamma secretion in neonates and subsequent atopy
31. Respiratory and irritant health effects of ambient volatile organic compounds
32. Is deficiency of interferon gamma production by allergen triggered cord blood cells a predictor of atopic eczema?
33. Bidirectional cytokine interactions in the maternal-fetal relationship: Is successful pregnancy a TH2 phenomenon?
34. Asthma and the indoor environment: The significance of emission of formaldehyde and volatile organic compounds from newly painted indoor surfaces