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Volumn 4, Issue 3, 2009, Pages 203-210

TNNI3K could be a novel molecular target for the treatment of cardiac diseases

Author keywords

Apoptosis; Cardiac ankyrin repeats; Cardiac contraction; Cardiac hypertrophy; Cardiac troponin I; Diagnosis agents; Ischemia injury; Molecular therapeutics; Myocardial infarction; TNNI3K

Indexed keywords

ANKYRIN; CARDIOTONIC AGENT; DIGITALIS; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXIREDOXIN 3; PROTEIN TNN13K; STRESS ACTIVATED PROTEIN KINASE; TROPONIN I; UNCLASSIFIED DRUG;

EID: 76149135724     PISSN: 15748901     EISSN: None     Source Type: Journal    
DOI: 10.2174/157489009789152285     Document Type: Review
Times cited : (6)

References (25)
  • 1
    • 76149110280 scopus 로고    scopus 로고
    • Yorinaka, H., Ding, J.F., Meng, X.M.: WO2006057278 (2006).
    • Yorinaka, H., Ding, J.F., Meng, X.M.: WO2006057278 (2006).
  • 2
    • 76149145536 scopus 로고    scopus 로고
    • Yorinaka, H., Ding, J.F., Meng, X.M.: EP1832299 (2007).
    • Yorinaka, H., Ding, J.F., Meng, X.M.: EP1832299 (2007).
  • 4
    • 0038275985 scopus 로고    scopus 로고
    • Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I
    • Zhao Y, Meng XM, Wei YJ, et al. Cloning and characterization of a novel cardiac-specific kinase that interacts specifically with cardiac troponin I. J Mol Med 2003; 81: 297-304.
    • (2003) J Mol Med , vol.81 , pp. 297-304
    • Zhao, Y.1    Meng, X.M.2    Wei, Y.J.3
  • 6
    • 41149175602 scopus 로고    scopus 로고
    • MEF2C is an essential regulatory element required for unique expression of the cardiac-specific CARK gene
    • Wang H, Chen C, Song X, et al. MEF2C is an essential regulatory element required for unique expression of the cardiac-specific CARK gene. J Cell Mol Med 2008; 12: 304-315.
    • (2008) J Cell Mol Med , vol.12 , pp. 304-315
    • Wang, H.1    Chen, C.2    Song, X.3
  • 7
    • 34548789645 scopus 로고    scopus 로고
    • Identification of the dual specificity and the functional domains of the cardiac - specific protein kinase TNNI3K. Gen
    • Feng Y, Cao HQ, Liu Z, Ding JF, Meng XM. Identification of the dual specificity and the functional domains of the cardiac - specific protein kinase TNNI3K. Gen Phys B 2007; 26: 104-109.
    • (2007) Phys B , vol.26 , pp. 104-109
    • Feng, Y.1    Cao, H.Q.2    Liu, Z.3    Ding, J.F.4    Meng, X.M.5
  • 8
    • 36448937132 scopus 로고    scopus 로고
    • AOP-1 interacts with cardiacspecific protein kinase TNNI3K and down-regulates its kinase activity
    • Feng Y, Liu DQ, Wang Z, et al. AOP-1 interacts with cardiacspecific protein kinase TNNI3K and down-regulates its kinase activity. Biochemistry (Mosc) 2007; 72: 1199-1204.
    • (2007) Biochemistry (Mosc) , vol.72 , pp. 1199-1204
    • Feng, Y.1    Liu, D.Q.2    Wang, Z.3
  • 9
    • 52449132084 scopus 로고    scopus 로고
    • Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury
    • Lai ZF, Chen YZ, Feng LP, et al. Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury. Am J Physiol Heart Circ Physiol 2008; 295: H708-716.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Lai, Z.F.1    Chen, Y.Z.2    Feng, L.P.3
  • 10
    • 68949130189 scopus 로고    scopus 로고
    • The cardiac pacemakerspecific channel Hcn4 is a direct transcriptional target of MEF2
    • Kuratomi S, Ohmori Y, Ito M, et al. The cardiac pacemakerspecific channel Hcn4 is a direct transcriptional target of MEF2. Cardiovasc Res 2009; 83(4): 682-687.
    • (2009) Cardiovasc Res , vol.83 , Issue.4 , pp. 682-687
    • Kuratomi, S.1    Ohmori, Y.2    Ito, M.3
  • 11
    • 0034958883 scopus 로고    scopus 로고
    • Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues
    • Bennett V, Baines AJ. Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues. Physiol Rev 2001; 81: 1353-1392.
    • (2001) Physiol Rev , vol.81 , pp. 1353-1392
    • Bennett, V.1    Baines, A.J.2
  • 12
    • 0242464931 scopus 로고    scopus 로고
    • Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
    • Mohler PJ, Schott JJ, Gramolini AO, et al. Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature 2003; 421: 634-639.
    • (2003) Nature , vol.421 , pp. 634-639
    • Mohler, P.J.1    Schott, J.J.2    Gramolini, A.O.3
  • 13
    • 0038796687 scopus 로고    scopus 로고
    • Hearts of this ILK rely on TNNI3K, a MAPKKK that regulated TNNI3
    • Luft FC. Hearts of this ILK rely on TNNI3K, a MAPKKK that regulated TNNI3. J Mol Med 2003; 81: 279-280.
    • (2003) J Mol Med , vol.81 , pp. 279-280
    • Luft, F.C.1
  • 14
    • 76149126592 scopus 로고    scopus 로고
    • Suppression of multiple pathwaymediated apoptosis is involved in protective effects of TNNI3K on hypoxia-induced injury in rat neonatal cardiomyocytes
    • Unpublished
    • Li P, Meng XM, Lai ZF, et al. Suppression of multiple pathwaymediated apoptosis is involved in protective effects of TNNI3K on hypoxia-induced injury in rat neonatal cardiomyocytes. Cardiovasc Res 2009: [Unpublished].
    • (2009) Cardiovasc Res
    • Li, P.1    Meng, X.M.2    Lai, Z.F.3
  • 15
    • 0142247618 scopus 로고    scopus 로고
    • The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules
    • Miller MK, Bang ML, Witt CC, et al. The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules. J Mol Biol 2003; 333: 951-964.
    • (2003) J Mol Biol , vol.333 , pp. 951-964
    • Miller, M.K.1    Bang, M.L.2    Witt, C.C.3
  • 16
    • 76149139577 scopus 로고    scopus 로고
    • TNNI3K, a cardiac-specific kinase, promotes cardiac hypertrophy in vivo. (AHA Meeting Abstracts)
    • II-5
    • Wang XJ, Yang X, Chen JZ, et al. TNNI3K, a cardiac-specific kinase, promotes cardiac hypertrophy in vivo. (AHA Meeting Abstracts). Circulation 2006; 114 (Suppl): II-5.
    • (2006) Circulation , vol.114 , Issue.SUPPL.
    • Wang, X.J.1    Yang, X.2    Chen, J.Z.3
  • 17
    • 76149115384 scopus 로고    scopus 로고
    • Wang HM, Gao MM, Xiao B, et al. Investigation on mutation of cardiac troponin I-interacting kinase TNNI3K gene in patients with cardiac hypertrophy. Chin J Cardiovasc Dis (in Chinese) 2004; 32: 741-742.
    • Wang HM, Gao MM, Xiao B, et al. Investigation on mutation of cardiac troponin I-interacting kinase TNNI3K gene in patients with cardiac hypertrophy. Chin J Cardiovasc Dis (in Chinese) 2004; 32: 741-742.
  • 18
    • 0035834816 scopus 로고    scopus 로고
    • Untangling the Web: Specific signaling from PKC isoforms to MAPK cascades
    • Clerk A, Sugden PH. Untangling the Web: Specific signaling from PKC isoforms to MAPK cascades. Cir Res 2001; 89: 847-849.
    • (2001) Cir Res , vol.89 , pp. 847-849
    • Clerk, A.1    Sugden, P.H.2
  • 20
    • 76149085335 scopus 로고    scopus 로고
    • Schenttler, R.A., Jones Jr., W.D., Claxton, G.P.: US4670450 (1985).
    • Schenttler, R.A., Jones Jr., W.D., Claxton, G.P.: US4670450 (1985).
  • 23
    • 76149137075 scopus 로고    scopus 로고
    • US20080081344
    • Hess, G., Hess, A.: US20080081344 (2008).
    • (2008)
    • Hess, G.1    Hess, A.2
  • 25
    • 76149090009 scopus 로고    scopus 로고
    • US20080032929
    • Jin, J.-P.: US20080032929 (2008).
    • (2008)
    • Jin, J.-P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.