Proteolytic cleavage of versican during limb joint development

Anatomical Record

Volumn 293, Issue 2, 2010, Pages 208-214

  Capehart, Anthony A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

ECM; Joint interzone; Limb development; Synovial joint development; Versican

Indexed keywords

ADAMTS1 PROTEIN; AMINO ACID DERIVATIVE; ASPARTYLPROLYLGLUTAMYLALANYLALANYLGLUTAMINE; PROTEIN ADAMTS; PROTEINASE; UNCLASSIFIED DRUG; VERSICAN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; JOINT; JOINT CAVITY; LIMB DEVELOPMENT; MOUSE; NONHUMAN; POSTCOITAL TEST; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING;

ADAM PROTEINS; ANIMALS; FORELIMB; GESTATIONAL AGE; HINDLIMB; IMMUNOHISTOCHEMISTRY; JOINT CAPSULE; MICE; MORPHOGENESIS; PEPTIDE FRAGMENTS; PROTEIN PROCESSING, POST-TRANSLATIONAL; VERSICANS;

EID: 76149121798     PISSN: 19328486     EISSN: 19328494     Source Type: Journal    
DOI: 10.1002/ar.21049     Document Type: Article

References (37)

1. Ang LC, Zhang Y, Cao L, Yang BL, Young B, Kiani C, Lee V, Allan K, Yang BB. 1999. Versican enhances locomotion of astrocytoma cells and reduces cell adhesion through its G1 domain. J Neuropathol Exp Neurol 58:597-605.
2. Archer CW, Morrison H, Pitsillides AA. 1994. Cellular aspects of the development of diarthroidal joints and articular cartilage. J Anat 184:447-456.
3. Craig FM, Bayliss MT, Bentley G, Archer CW. 1990. A role for hyaluronan in joint development. J Anat 171:17-23.
4. Craig FM, Bentley G, Archer CW. 1987. The spatial and temporal pattern of collagens I and II and keratin sulphate in the developing chick metatarsophalangeal joint. Development 99:383-391.
5. Garciadiego-Cazares D, Rosales C, Katoh M, Cimal-Monroy J. 2004. Coordination of chondrocyte differentiation and joint formation by α5β1 integrin in the developing appendicular skeleton. Development 131:4735-4742.
6. Kamiya N, Watanabe H, Habuchi H, Takagi H, Shinomura T, Shimizu K, Kimata K. 2006. Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation. J Biol Chem 281:2390-2400.
7. Kaufman MH. 1995. The atlas of mouse development. London: Academic Press.
8. Kern CB, Norris RA, Thompson RP, Argraves WS, Fairey SE, Reyes L, Hoffman S, Markwald RR, Mjaatvedt CH. 2007. Versican proteolysis mediates myocardial regression during outflow tract development. Dev Dyn 236:671-683.
9. Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe M, Argraves WS. 2006. Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn 235:2238-2247.
10. Kimata K, Oike Y, Tani K, Shinomura T, Yamagata M, Uritani M, Suzuki S. 1986. A large chondroitin sulfate proteoglycan (PG-M) synthesized before chondrogenesis in the limb bud of chick embryo. J Biol Chem 261:13517-13525.
11. Little CB, Mittaz L, Belluoccio D, Rogerson FM, Campbell IK, Meeker CT, Bateman JF, Pritchard MA, Fosang AJ. 2005. ADAMTS-1 knockout mice do not exhibit abnormalities in aggrecan turnover in vitro or in vivo. Arthritis Rheum 52:1461-1472.
12. Longpre JM, McCulloch DR, Koo BH, Alexander JP, Apte SS, Leduc R. 2009. Characterization of ADAMTS5 processing by proprotein convertases. Int J Biochem Cell Biol 41:1116-1126.
13. Matsumoto K, Shionyu M, Go M, Shimizu K, Shinomura T, Kimata K, Watanabe H. 2003. Distinct interaction of versican/PG-M with hyaluronan and link protein. J Biol Chem 278:41205-41212.
14. McCulloch DR, Goff CL, Bhatt S, Dixon LJ, Sandy JD, Apte SS. 2009. Adamts5, the gene encoding a proteoglycan-degrading metalloprotease is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Exp Patterns 9:314-323.
15. Mitrovic D. 1978. Development of the diarthroidal joints in the rat embryo. Am J Anat 151:475-485.
16. Mjaatvedt CH, Yamamura H, Capehart AA, Turner D, Markwald RR. 1998. The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation. Dev Biol 202:56-66.
17. Pacifici M, Iwamoto M, Golden EB, Leatherman JL, Lee YS, Chuong CM. 1993. Tenascin is associated with articular cartilage development. Dev Dyn 198:123-134.
18. Pacifici M, Koyama E, Iwamoto M. 2005. Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries. Birth Defects Res 75:237-248.
19. Pitsillides AA, Archer CW, Prehm P, Bayliss MT, Edwards JC. 1995. Alterations in hyaluronan synthesis during developing joint cavitation. J Histochem Cytochem 43:263-273.
20. Rodriguez-Manzaneque JC, Westling J, Thai SN, Luque A, Knauper V, Murphy G, Sandy JD, Iruela-Arispe ML. 2002. ADAMTS-1 cleaves aggrecan at multiple sites and is differentially inhibited by metalloproteinase inhibitors. Biochem Biophys Res Commun 293:501-508.
21. Russell DL, Doyle KM, Ochsner SA, Sandy JD, Richards JS. 2003. Processing and localization of ADAMTS-1 and proteolytic cleavage of versican during cumulus matrix expansion and ovulation. J Biol Chem 278:42330-42339.
22. Sandy JD, Westling J, Kenagy RD, Iruela-Arispe ML, Verscharen C, Rodriguez-Mazaneque JC, Zimmermann DR, Lemire JM, Fischer JW, Wight TN, Clowes AW. 2001. Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4. J Biol Chem 276:13372-13378.
23. Shepard JB, Gliga DA, Morrow AP, Hoffman S, Capehart AA. 2008. Versican knock-down compromises chondrogenesis in the embryonic chick limb. Anat Rec 291:19-27.
24. Shepard JB, Krug HA, LaFoon BA, Hoffman S, Capehart AA. 2007. Versican expression during synovial joint morphogenesis. Int J Biol Sci 3:380-384.
25. Shibata S, Fukada K, Imai H, Abe T, Yamashita Y. 2003. In situ hybridization and immunohistochemistry of versican, aggrecan, and link protein, and histochemistry of hyaluronan in the developing mouse limb bud cartilage. J Anat 203:425-432.
26. Shinomura T, Nishida Y, Ito K, Kimata K. 1993. DNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. Alternative spliced multiforms of PG-M and their relationships to versican. J Biol Chem 268:14461-14469.
27. Snow HE, Riccio LM, Hoffman S, Mjaatvedt CH, Capehart AA. 2005. Versican expression during skeletal/joint morphogenesis and patterning of muscle and nerve in the embryonic mouse limb. Anat Rec 282:95-105.
28. Wachsmuth L, Bau B, Fan Z, Pecht A, Gerwin N, Aigner T. 2004. ADAMTS-1, a gene product of articular chondrocytes in vivo and in vitro, is downregulated by interleukin 1beta. J Rheumatol 31:315-320.
29. Williams DR, Presar AR, Richmond AT, Mjaatvedt CH, Hoffman S, Capehart AA. 2005. Limb chondrogenesis is compromised in the versican deficient hdf mouse. Biochem Biophys Res Comm 334: 960-966.
30. Wu YJ, La Pierre DP, Wu J, Yee AJ, Yang BB. 2005. The interaction of versican with its binding partners. Cell Res 15:483-494.
31. Yamamura H, Zhang M, Markwald RR, Mjaatvedt CH. 1997. A heart segmental defect in the anterior-posterior axis of a transgenic mutant mouse. Dev Biol 186:58-72.
32. Yang BL, Zhang Y, Cao L, Yang BB. 1999. Cell adhesion and proliferation mediated through the G1 domain of versican. J Cell Biochem 72:210-220.
33. Zako M, Shinomura T, Ujita M, Ito K, Kimata K. 1995. Expression of PG-M (V3), an alternatively spliced form of PG-M without a chondroitin sulfate attachment region in mouse and human tissues. J Biol Chem 270:3914-3918.
34. Zhang Y, Cao L, Kiana C, Yang BL, Hu W, Yang BB. 1999. Promotion of chondrocyte proliferation by versican mediated by G1 domain and EGF-like motifs. J Cell Biochem 73:445-457.
35. Zhang Y, Cao L, Kiani BL, Yang BL, Yang BB. 1998a. The G3 domain of versican inhibits mesenchymal chondrogenesis via the epidermal growth factor-like motifs. J Biol Chem 273:33054-33063.
36. Zhang Y, Cao L, Yang BL, Yang BB. 1998b. The G3 domain of versican enhances cell proliferation via epidermal growth factor-like motifs. J Biol Chem 273:21342-21351.
37. Zimmermann DR, Ruoslahti E. 1989. Multiple domains of the large fibroblast proteoglycan, versican. EMBO J 8:2975-2981.