Design, synthesis and biologic evaluation of diarylbenzimidazole derivatives as novel HIV-I non-nucleoside reverse transcriptase inhibitors

Yaoxue Xuebao

Volumn 44, Issue 11, 2009, Pages 1233-1243

  Qin, Bing Jie ^a   Zhou, Ting ^a   Lu, Hong ^b   Jiang, Shi Bo ^b   Xie, Lan ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b NEW YORK BLOOD CENTER   (United States)

Author keywords

Diarylbenzimidazole derivative; HIV 1 NNRTIs; Synthesis

Indexed keywords

1,2 DIARYLBENZIMIDAZOLE; 1,6 DIARYLBENZIMIDAZOLE; ANILINE DERIVATIVE; DIARYLBENZIMIDAZOLE DERIVATIVE; IMIDAZOLE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MOLECULAR DOCKING; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; VIRUS REPLICATION;

ANTI-HIV AGENTS; BENZIMIDAZOLES; CELL LINE; DRUG DESIGN; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MOLECULAR STRUCTURE; REVERSE TRANSCRIPTASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 76049101002     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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