A novel methodology for multicomponent drug design and its application in optimizing the combination of active components from Chinese medicinal formula shenmai

Chemical Biology and Drug Design

Volumn 75, Issue 3, 2010, Pages 318-324

  Wang, Yi ^a   Yu, Lingyan ^a   Zhang, Ling ^a   Qu, Haibin ^a   Cheng, Yiyu ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Drug design; Multitarget drug; Quantitative composition activity relationship; Traditional Chinese medicine

Indexed keywords

CHINESE DRUG; OPHIOPONIN DERIVATIVE; PANAXADIOL; PANAXATRIOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHINESE MEDICINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG STRUCTURE; HEART INFARCTION; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; DRUG COMBINATIONS; DRUG DESIGN; DRUGS, CHINESE HERBAL; MEDICINE, CHINESE TRADITIONAL; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 76049092233     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2009.00934.x     Document Type: Article

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