RUNspike, a complementary virus filter spiking method: A solution to the problem of reduced throughput due to the addition of the virus spike

PDA Journal of Pharmaceutical Science and Technology

Volumn 63, Issue 6, 2009, Pages 547-558

  Parrella, Joe ^a   Wu, Yaling ^b   Kahn, David W ^b   Genest, Paul ^a  

^a MILLIPORE CORPORATION   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Complementary RUNspike method; Percent flow decay; PVDF parvovirus filter; Spiking studies; Traditional virus spiking method; Virus stock solution contaminants; Volumetric throughput (L m2)

Indexed keywords

POLYVINYLIDENE FLUORIDE;

ARTICLE; BIOLOGICAL MONITORING; CONTROLLED STUDY; DRUG MANUFACTURE; FILTER DESIGN; FILTRATION; HYDRAULIC CONDUCTIVITY; INTERMETHOD COMPARISON; NONHUMAN; PARVOVIRUS; RUNSPIKE METHOD; TECHNIQUE; VALIDATION PROCESS; VIRUS FILTER SPIKING; VOLUMETRY;

DRUG CONTAMINATION; DRUG INDUSTRY; FILTRATION; PARVOVIRUS; PHARMACEUTICAL PREPARATIONS; POLYVINYLS; QUALITY CONTROL; VIRUSES;

EID: 76049085905     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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