Normal-flow virus filtration: Detection and assessment of the endpoint in bioprocessing

Biotechnology and Applied Biochemistry

Volumn 42, Issue 2, 2005, Pages 133-142

  Bolton, Glen ^a   Cabatingan, Mark ^a   Rubino, Mike ^b   Lute, Scott ^c   Brorson, Kurt ^c   Bailey, Mark ^b  

^a MILLIPORE CORPORATION   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Bioprocessing; Log (reduction value); Murine minute virus; Normal flow virus filtration; Pore plugging model; Virus breakthrough

Indexed keywords

ADSORPTION; BACTERIA; DRUG PRODUCTS; FILTRATION; MATHEMATICAL MODELS;

BIOPROCESSING; LOG (REDUCTION VALUE); MURINE MINUTE VIRUS; NORMAL FLOW VIRUS FILTRATION; PORE-PLUGGING MODEL; VIRUS BREAKTHROUGH;

VIRUSES;

IMMUNOGLOBULIN G;

ADSORPTION; ARTICLE; BACTERIOPHAGE; BIOPROCESS; CONTROLLED STUDY; DRUG INDUSTRY; FOULING CONTROL; HUMAN; MATHEMATICAL MODEL; MEMBRANE FILTER; NONHUMAN; PARVOVIRUS; THEORETICAL MODEL; VIRUS DETECTION;

ANIMALS; BACTERIOPHAGE PHI X 174; CELL LINE; HUMANS; MICE; MINUTE VIRUS OF MICE; MODELS, BIOLOGICAL; ULTRAFILTRATION;

COLIPHAGE PHIX174; MAMMALIA; MICE MINUTE VIRUS; PARVOVIRUS;

EID: 25144484795     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20050056     Document Type: Article

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