Filter preconditioning enables representative scaled-down modelling of filter capacity and viral clearance by mitigating the impact of virus spike impurities

Biotechnology and Applied Biochemistry

Volumn 52, Issue 4, 2009, Pages 293-301

  Khan, Navid Z ^a   Parrella, Joseph J ^a   Genest, Paul W ^a   Colman, Michael S ^a  

^a MILLIPORE CORPORATION   (United States)

Author keywords

Filter fouling; Flow decay; Log reduction value (LRV); Spiking study; Viral clearance; Viral safety

Indexed keywords

FILTER FOULING; FLOW DECAY; LOG REDUCTION VALUE (LRV); SPIKING STUDY; VIRAL CLEARANCE; VIRAL SAFETY;

HYDRAULICS; POROUS MATERIALS;

MICROFILTRATION;

ARTICLE; BIOFILTER; BIOFILTRATION; FILTER DESIGN; HIGH THROUGHPUT SCREENING; HYDRAULIC PERMEABILITY; INSTRUMENT STERILIZATION; NONHUMAN; PERFORMANCE MEASUREMENT SYSTEM; PROCESS DEVELOPMENT; VALIDATION STUDY; VIRAL CONTAMINATION; VIRUS FILTRATION; VIRUS INHIBITION; VIRUS ISOLATION; BACTERIOPHAGE; BIOLOGICAL MODEL; COMPUTER SIMULATION; DRUG CONTAMINATION; INSTRUMENTATION; ISOLATION AND PURIFICATION; METHODOLOGY; PHYSIOLOGY; ULTRAFILTRATION;

BACTERIOPHAGES; COMPUTER SIMULATION; DRUG CONTAMINATION; MODELS, BIOLOGICAL; ULTRAFILTRATION;

EID: 66149112921     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20080133     Document Type: Article

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