메뉴 건너뛰기




Volumn 335, Issue 1-2, 2010, Pages 83-89

JNK1/2 siRNA inhibits transforming-growth factor-β1-induced connective tissue growth factor expression and fibrotic function in THSFs

Author keywords

Cornea; CTGF; JNK; SiRNA; TGF

Indexed keywords

COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE 1; TELOMERASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 75949114635     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-009-0245-8     Document Type: Article
Times cited : (17)

References (24)
  • 1
    • 38549159026 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of fibrosis
    • DOI 10.1002/path.2277
    • TA Wynn 2008 Cellular and molecular mechanisms of fibrosis J Pathol 214 199 210 10.1002/path.2277 1:CAS:528:DC%2BD1cXhvFCkt7w%3D 18161745 (Pubitemid 351160157)
    • (2008) Journal of Pathology , vol.214 , Issue.2 , pp. 199-210
    • Wynn, T.A.1
  • 2
    • 33644967568 scopus 로고    scopus 로고
    • The role of CTGF, TGF and Smad signaling pathway in corneal wound healing
    • 1:CAS:528:DC%2BD28XhsFygu7o%3D
    • XY Wu YM Yang H Guo Y Chang 2006 The role of CTGF, TGF and Smad signaling pathway in corneal wound healing Cornea Chin Med J 119 57 62 1:CAS:528:DC%2BD28XhsFygu7o%3D
    • (2006) Cornea Chin Med J , vol.119 , pp. 57-62
    • Wu, X.Y.1    Yang, Y.M.2    Guo, H.3    Chang, Y.4
  • 3
    • 0242708522 scopus 로고    scopus 로고
    • Transforming growth factor-β1 expression in cultured corneal fibroblasts in response to injury
    • DOI 10.1002/(SICI)1097-4644(20000501)77:2<186::AID-JCB3>3.0.CO;2-M
    • QH Song RP Singh TP Richardson MA Nugent V Trinkaus-Randall 2000 Transforming growth factor-beta1 expression in cultured corneal fibroblasts in response to injury J Cell Biochem 77 186 199 10.1002/(SICI)1097-4644(20000501) 77:2<186::AID-JCB3>3.0.CO;2-M 1:CAS:528:DC%2BD3cXit1GktLc%3D 10723086 (Pubitemid 30176649)
    • (2000) Journal of Cellular Biochemistry , vol.77 , Issue.2 , pp. 186-199
    • Song, Q.H.1    Singh, R.P.2    Richardson, T.P.3    Nugent, M.A.4    Trinkaus-Randall, V.5
  • 4
    • 0029816069 scopus 로고    scopus 로고
    • Stimulation of fibroblast cell growth, matrix production and granulation tissue formation by connective tissue growth factor
    • 10.1111/1523-1747.ep12363389 1:CAS:528:DyaK28XlvVOnsrg%3D 8751978
    • K Frazier S Williams D Kothapalli H Klapper GR Grotendorst 1996 Stimulation of fibroblast cell growth, matrix production and granulation tissue formation by connective tissue growth factor J Invest Dermatol 107 404 411 10.1111/1523-1747.ep12363389 1:CAS:528:DyaK28XlvVOnsrg%3D 8751978
    • (1996) J Invest Dermatol , vol.107 , pp. 404-411
    • Frazier, K.1    Williams, S.2    Kothapalli, D.3    Klapper, H.4    Grotendorst, G.R.5
  • 5
    • 0029808645 scopus 로고    scopus 로고
    • A novel transforming growth factor β response element controls the expression of the connective tissue growth factor gene
    • 1:CAS:528:DyaK28XitFegt7k%3D 9052988
    • GR Grotendorst H Okochi N Hayashi 1996 A novel transforming growth factor β response element controls the expression of the connective tissue growth factor gene Cell Growth Differ 7 469 480 1:CAS:528:DyaK28XitFegt7k%3D 9052988
    • (1996) Cell Growth Differ , vol.7 , pp. 469-480
    • Grotendorst, G.R.1    Okochi, H.2    Hayashi, N.3
  • 6
    • 0027229995 scopus 로고
    • Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair
    • 1:CAS:528:DyaK3sXmtVWjtrY%3D 8374172
    • A Igarashi H Okochi DM Bradham GR Grotendorst 1993 Regulation of connective tissue growth factor gene expression in human skin fibroblasts and during wound repair Mol Biol Cell 4 637 645 1:CAS:528:DyaK3sXmtVWjtrY%3D 8374172
    • (1993) Mol Biol Cell , vol.4 , pp. 637-645
    • Igarashi, A.1    Okochi, H.2    Bradham, D.M.3    Grotendorst, G.R.4
  • 7
    • 0026055366 scopus 로고
    • Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
    • 10.1083/jcb.114.6.1285 1:CAS:528:DyaK38Xhs1Knsb0%3D 1654338
    • DM Bradham A Igarashi RL Potter GR Grotendorst 1991 Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10 J Cell Biol 114 1285 1294 10.1083/jcb.114.6.1285 1:CAS:528:DyaK38Xhs1Knsb0%3D 1654338
    • (1991) J Cell Biol , vol.114 , pp. 1285-1294
    • Bradham, D.M.1    Igarashi, A.2    Potter, R.L.3    Grotendorst, G.R.4
  • 9
    • 33845662322 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF) acts as a downstream mediator of TGF-β1 to induce mesenchymal cell condensation
    • DOI 10.1002/jcp.20850
    • JJ Song R Aswad RA Kanaan MC Rico TA Owen MF Barbe FF Safadi SN Popoff 2007 Connective tissue growth factor (CTGF) acts as a downstream mediator of TGF-beta1 to induce mesenchymal cell condensation J Cell Physiol 210 398 410 10.1002/jcp.20850 1:CAS:528:DC%2BD28XhtlGqsbbO 17111364 (Pubitemid 44956885)
    • (2007) Journal of Cellular Physiology , vol.210 , Issue.2 , pp. 398-410
    • Song, J.J.1    Aswad, R.2    Kanaan, R.A.3    Rico, M.C.4    Owen, T.A.5    Barbe, M.F.6    Safadi, F.F.7    Popoff, S.N.8
  • 10
    • 0037636775 scopus 로고    scopus 로고
    • 2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-β1 in human lung fibroblasts
    • DOI 10.1165/rcmb.4892
    • M Utsugi K Dobashi T Ishizuka K Masubuchi Y Shimizu T Nakazawa M Mori 2003 C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts Am J Respir Cell Mol Biol 28 754 761 10.1165/rcmb.4892 1:CAS:528: DC%2BD3sXks1KitL4%3D 12760970 (Pubitemid 36677180)
    • (2003) American Journal of Respiratory Cell and Molecular Biology , vol.28 , Issue.6 , pp. 754-761
    • Utsugi, M.1    Dobashi, K.2    Ishizuka, T.3    Masubuchi, K.4    Shimizu, Y.5    Nakazawa, T.6    Mori, M.7
  • 12
    • 0031225015 scopus 로고    scopus 로고
    • Connective tissue growth factor: A mediator of TGf-β action on fibroblasts
    • DOI 10.1016/S1359-6101(97)00010-5, PII S1359610197000105
    • GR Grotendorst 1997 Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts Cytokine Growth Factor Rev 8 171 179 10.1016/S1359-6101(97)00010-5 1:CAS:528:DyaK1cXjsVWmsA%3D%3D 9462483 (Pubitemid 28077925)
    • (1997) Cytokine and Growth Factor Reviews , vol.8 , Issue.3 , pp. 171-179
    • Grotendorst, G.R.1
  • 13
    • 0141957067 scopus 로고    scopus 로고
    • Role of TGF-beta in the progression of renal fibrosis
    • K Tamaki S Okuda 2003 Role of TGF-beta in the progression of renal fibrosis Contrib Nephrol 139 97 109
    • (2003) Contrib Nephrol , vol.139 , pp. 97-109
    • Tamaki, K.1    Okuda, S.2
  • 15
    • 44849087809 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: Statins with forskolin block TGFbeta1-induced CCN2/CTGF expression
    • 10.1074/jbc.M710363200 1:CAS:528:DC%2BD1cXksFagtbw%3D 18287089
    • SA Black PC Trackman 2008 Transforming growth factor-beta1 (TGFbeta1) stimulates connective tissue growth factor (CCN2/CTGF) expression in human gingival fibroblasts through a RhoA-independent, Rac1/Cdc42-dependent mechanism: statins with forskolin block TGFbeta1-induced CCN2/CTGF expression J Biol Chem 283 10835 10847 10.1074/jbc.M710363200 1:CAS:528:DC%2BD1cXksFagtbw%3D 18287089
    • (2008) J Biol Chem , vol.283 , pp. 10835-10847
    • Black, S.A.1    Trackman, P.C.2
  • 16
    • 0034796416 scopus 로고    scopus 로고
    • Transforming growth factor-beta-stimulated connective tissue growth factor expression during corneal myofibroblast differentiation
    • 1:STN:280:DC%2BD3MrjsVWgtg%3D%3D 11581194
    • PA Folger D Zekaria G Grotendorst 2001 Transforming growth factor-beta-stimulated connective tissue growth factor expression during corneal myofibroblast differentiation Invest Ophthalmol Vis Sci 42 2534 2541 1:STN:280:DC%2BD3MrjsVWgtg%3D%3D 11581194
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2534-2541
    • Folger, P.A.1    Zekaria, D.2    Grotendorst, G.3
  • 18
    • 0142244187 scopus 로고    scopus 로고
    • Mediation of transforming growth factor-β1-stimulated matrix contraction by fibroblasts: A role for connective tissue growth factor in contractile scarring
    • 1:CAS:528:DC%2BD3sXpsVWlur0%3D 14578203
    • JT Daniels GS Schultz TD Blalock 2003 Mediation of transforming growth factor-β1-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring Am J Pathol 163 2043 2052 1:CAS:528:DC%2BD3sXpsVWlur0%3D 14578203
    • (2003) Am J Pathol , vol.163 , pp. 2043-2052
    • Daniels, J.T.1    Schultz, G.S.2    Blalock, T.D.3
  • 19
    • 70349254140 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinases 1/2 in transforming growth factor beta1-induced expression of connective tissue growth factor and scar formation in the cornea
    • 1:CAS:528:DC%2BD1MXhtFSqtrfL 19589256
    • Y Chang XY Wu 2009 The role of c-Jun N-terminal kinases 1/2 in transforming growth factor beta1-induced expression of connective tissue growth factor and scar formation in the cornea J Int Med Res 37 3 727 736 1:CAS:528:DC%2BD1MXhtFSqtrfL 19589256
    • (2009) J Int Med Res , vol.37 , Issue.3 , pp. 727-736
    • Chang, Y.1    Wu, X.Y.2
  • 20
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-β signal transduction
    • M Aristidis S Serhiy CH Heldin 2001 Smad regulation in TGF-β signal transduction J Cell Sci 114 4359 4369
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Aristidis, M.1    Serhiy, S.2    Heldin, C.H.3
  • 21
    • 23844514359 scopus 로고    scopus 로고
    • SMAD pathway mediation of BDNF and TGFβ2 regulation of proliferation and differentiation of hippocampal granule neurons
    • DOI 10.1242/dev.01893
    • J Lu Y Wu N Sousa FX Osborne 2005 SMAD pathway mediation of BDNF and TGF2 regulation of proliferation and differentiation of hippocampal granule neurons Development 132 3231 3242 10.1242/dev.01893 1:CAS:528:DC%2BD2MXosVemu7k%3D 15958511 (Pubitemid 41167151)
    • (2005) Development , vol.132 , Issue.14 , pp. 3231-3242
    • Lu, J.1    Wu, Y.2    Sousa, N.3    Almeida, O.F.X.4
  • 23
    • 0036905524 scopus 로고    scopus 로고
    • EGF-induced ERK phosphorylation independent of PKC isozymes in human corneal epithelial cells
    • 12454035
    • KP Xu DA Dartt FS Yu 2002 EGF-induced ERK phosphorylation independent of PKC isozymes in human corneal epithelial cells Invest Ophthalmol Vis Sci 43 3673 3679 12454035
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3673-3679
    • Xu, K.P.1    Dartt, D.A.2    Yu, F.S.3
  • 24
    • 0344688189 scopus 로고    scopus 로고
    • Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells
    • DOI 10.1016/j.exer.2003.09.002
    • Y Wang J Zhang XJ Yi FS Yu 2004 Activation of ERK1/2 MAP kinase pathway induces tight junction disruption in human corneal epithelial cells Exp Eye Res 78 125 136 10.1016/j.exer.2003.09.002 1:CAS:528:DC%2BD3sXps1eru7w%3D 14667834 (Pubitemid 37518251)
    • (2004) Experimental Eye Research , vol.78 , Issue.1 , pp. 125-136
    • Wang, Y.1    Zhang, J.2    Yi, X.-J.3    Yu, F.-S.X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.