Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: Implications for cancer cell behavior

American Journal of Pathology

Volumn 165, Issue 1, 2004, Pages 319-330

  Tan, Ernest Y ^a   Mujoomdar, Michelle ^a   Blay, Jonathan ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; CELL SURFACE PROTEIN; CHEMOKINE; COLLAGEN; DIPEPTIDYL PEPTIDASE IV; FIBRONECTIN; SCLEROPROTEIN;

ARTICLE; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CELL SURFACE; COLORECTAL CARCINOMA; CONTROLLED STUDY; DEAMINATION; DOWN REGULATION; ENZYME ACTIVITY; EXTRACELLULAR FLUID; FLOW CYTOMETRY; HUMAN; HUMAN CELL; METASTASIS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR PROMOTION;

EID: 3042552700     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63299-3     Document Type: Article

References (67)

1. Houghton AN, Albino AP, Cordon-Cardo C, Davis LJ, Eisinger M: Cell surface antigens of human melanocytes and melanoma. Expression of adenosine deaminase binding protein is extinguished with melanocyte transformation. J Exp Med 1988, 167:197-212
2. Dinjen WNM, Ten Kate J, van der Linden EPM, Wijnen JT, Khan PM, Bosman FT: Distribution of adenosine deaminase complexing protein (ADCP) in human tissues. J Histochem Cytochem 1989, 37:1869-1875
3. Morimoto C, Schlossman S: The structure and function of CD26 in the T-cell immune response. Immunol Rev 1998, 61:55-70
4. De Meester I, Korom S, Van Damme J, Scharpe S: CD26, let it cut orcut it down. Immunol Today 1999, 20:367-375
5. Drucker DJ: The glucagon-like peptides. Endocrinology 2001, 142: 521-527
6. Proost P, Menten P, Struyf S, Schutyser E, De Meester I, Van Damme J: Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78β into a most efficient monocyte attractant and CCR1 agonist. Blood 2000, 96:1674-1680
7. Bauvois B: A collagen-binding glycoprotein on the surface of mouse fibroblasts is identified as dipeptidyl peptidase IV. Biochem J 1988, 252:723-731
8. Hanski C, Hulhe T, Gossrau R, Reutter W: Direct evidence for the binding of rat liver DPP IV to collagen in vitro. Exp Cell Res 1988, 178:64-72
9. Piazza GA, Callanan HM, Mowery J, Hixson DC: Evidence for a role of dipeptidyl peptidase IV in fibronectin-mediated interactions of hepatocytes with extracellular matrix. Biochem J 1989, 262:327-334
10. Cheng HC, Abdel-Ghany M, Elble RC, Pauli BC: Lung endothelial dipeptidyl peptidase IV promotes adhesion and metastasis of rat breast cancer cells via tumor cell surface-associated fibronectin. J Biol Chem 1998, 273:24207-24215
11. Ghersi G, Dong H, Goldstein LA, Yeh Y, Hakkinen L, Larjava HS, Chen W-T: Regulation of fibroblast migration on collagenous matrix by a cell surface peptidase complex. J Biol Chem 2002, 277:29231-29241
12. Schrader WP, Pollara B: Localization of an adenosine deaminase-binding protein in human kidney. J Lab Clin Med 1978, 92:656-662
13. Schrader WP, West CA, Miczek AD, Norton EK: Characterization of the adenosine deaminase-adenosine deaminase complexing protein binding reaction. J Biol Chem 1990, 265:19312-19318
14. Dang NH, Morimoto C: CD26: an expanding role in immune regulation and cancer. Histol Histopathol 2002, 17:1213-1226
15. Morrison ME, Vijayasaradhi S, Engelstein D, Albino AP, Houghton AN: A marker for neoplastic progression of human melanocytes is a cell surface ectopeptidase. J Exp Med 1993, 177:1135-1143
16. Dinjens WNM, Ten Kate J, Kirch JAJM, Tanke HJ, van der Linden EPM, van den Ingh HFGM, Van Steenbrugge JV, Khan PM, Bosman FT: Adenosine deaminase complexing protein (ADCP) expression and metastatic potential in prostatic adenocarcinomas. J Pathol 1990, 160:195-201
17. Bogenrieder T, Finstad CL, Freeman RH, Papandreou CN, Scher HI, Albino AP, Reuter VE, Nanus DM: Expression and localization of aminopeptidase A, aminopeptidase N, and dipeptidyl peptidase IV in benign and malignant human prostate tissue. Prostate 1997, 33:225-232
18. Wesley UV, Albino AP, Iwari S, Houghton AN: A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells. J Exp Med 1999, 190:311-322
19. Pethiyagoda CL, Welch DR, Fleming TP: Dipeptidyl peptidase IV (DPPIV) inhibits cellular invasion of melanoma cells. Clin Exp Metastasis 2001, 18:391-400
20. Kajiyama H, Kikkawa F, Suzuki T, Shibata K, Ino K, Mizuani S: Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma. Cancer Res 2002, 62:2753-2757
21. Ten Kate J, Wijnen JT, Boldewijn J, Khan PM, Bosman FT: Immunohistochemical localization of adenosine deaminase complexing protein in intestinal mucosa and in colorectal adenocarcinoma as a marker for tumour cell heterogeneity. Histochem J 1985, 17:23-31
22. Ten Kate J, van den Ingh HFGM, Khan PM, Bosmans FT: Adenosine deaminase complexing protein (ADCP) immunoreactivity in colorectal adenocarcinoma. Int J Cancer 1986, 37:479-485
23. Stecca BA, Nardo B, Chieco P, Mazziotti A, Bolondi L, Cavallari A: Aberrant dipeptidyl peptidase IV (DPPIV/CD26) expression in human hepatocellular carcinoma. J Hepatol 1997, 27:337-345
24. Vaupel P, Kallinowski F, Okunieff P: Blood flow, oxygen and nutrient supply, and metabolic microenvironment in solid tumors: a review. Cancer Res 1989, 51:5139-5143
25. Headrick JP, Willis RJ: 5′-Nucleotidase activity and adenosine formation in stimulated, hypoxic and underperfused rat heart. Biochem J 1989, 261:541-550
26. Decking UK, Schlieper G, Kroll K, Schrader J: Hypoxia-induced inhibition of adenosine kinase potentiates cardiac adenosine release. Circ Res 1997, 81:154-164
27. Blay J, White TD, Hoskin DW: The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res 1997, 57:2602-2605
28. Hoskin DW, Reynolds T, Blay J: Adenosine as a possible inhibitor of killer T-cell activation in the microenvironment of solid tumours. Int J Cancer 1994, 59:854-855
29. 3 receptor to prevent the induction of murine anti-CD3-activated killer-T cells. Int J Cancer 2002, 99:386-395
30. 3 receptor. Cancer Res 1994, 54:3521-3526
31. 7 integrin-mediated adhesion of T lymphocytes to colon adenocarcinoma cells. Exp Cell Res 2002, 276:90-100
32. 2A purinergic receptor-mediated signaling in murine T cells. J Biol Chem 1997, 272:25881-25889
33. Barcz E, Sommer E, Janik P, Marianowski L, Skopinska-Rozewska E: Adenosine receptor antagonism causes inhibition of angiogenic activity of human ovarian cancer cells. Oncol Rep 2000, 7:1285-1291
34. Woodhouse EC, Amanatullah DF, Schetz JA, Liotta LA, Stracke ML, Clair T: Adenosine receptor mediates motility in human melanoma cells. Biochem Biophys Res Commun 1998, 246:888-894
35. Lelievre V, Muller J-M, Falcon J: Adenosine modulates cell proliferation in human colonic adenocarcinoma. I. Possible involvement of adenosine A1 receptor subtypes in HT29 cells. Eur J Pharmacol 1998, 341:289-297
36. Lelievre V, Muller J-M, Falcon J: Adenosine modulates cell proliferation in human colonic carcinoma. II. Differential behavior of HT29, DLD-1, Caco-2 and SW403 cell lines. Eur J Pharmacol 1998, 341: 299-308
37. Fishman P, Bar-Yehuda S, Ohana G, Pathak S, Wasserman L, Barer F, Multani AS: Adenosine acts as an inhibitor of lymphoma cell growth: a major role for the A3 adenosine receptor. Eur J Cancer 2000, 36:1452-1458
38. Merighi S, Mirandola P, Milani D, Varani K, Gessi S, Klotz KN, Leung E, Baraldi PG, Borea PA: Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells. J Invest Dermatol 2002, 119:923-933
39. Blay J, Brown KD: Functional receptors for epidermal growth factor in an epithelial-cell line derived from the rat small intestine. Biochem J 1985, 225:85-94
40. 1 adenosine receptors internalize together following agonist-induced receptor desensitization. J Biol Chem 1998, 273:17610-17617
41. Senesi S, Freer G, Gasperini M, Batoni G, Campa M: Complete release of adenosine deaminase from mouse lymphocytes stabilized by low-ph acetate. Biochim Biophys Acta 1988, 968:59-68
42. Mujoomdar M, Hoskin D, Blay J: Adenosine stimulation of the proliferation of colorectal carcinoma cell lines. Roles of cell density and adenosine metabolism. Biochem Pharmacol 2003, 66:1737-1747
43. Blay J, Poon ASL: Use of cultured permanent lines of intestinal epithelial cells for the assay of okadaic acid in mussel homogenates. Toxicon 1995, 33:739-746
44. Matzinger P: The JAM test. A simple assay for DNA fragmentation and cell death. J Immunol Methods 1991, 145:185-192
45. Sarret P, Gendron L, Kilian P, Nguyen HM, Gallo-Payet N, Payet MD, Beaudet A: Pharmacology and functional properties of NTS2 neurotensin receptors in cerebellar granule cells. J Biol Chem 2002, 277: 36233-36243
46. Skarpen E, Johannessen LE, Bjerk K, Fasteng H, Guren TK, Lindeman B, Thoresen GH, Christoffersen T, Stang E, Huitfeldt HS, Madshus IH: Endocytosed epidermal growth factor (EGF) receptors contribute to the EGF-mediated growth arrest in A431 cells by inducing a sustained increase in p21/CIP1. Exp Cell Res 1998, 243:161-172
47. 3 adenosine receptors and stimulates mast cell degranulation. J Clin Invest 1997, 100:2849-2857
48. Hasko G, Kuhel DG, Nemeth ZH, Mabley JG, Stachlewitz RF, Virag L, Lohinai Z, Southan GJ, Salzman AL, Szabo C: Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock. J Immunol 2000, 164: 1013-1019
49. Johnson RA, Yeung S-MH, Bushfield M, Stubner D, Shoshani I: "P"-site-mediated inhibition of adenylyl cyclase and its physiological implications. Role of Adenosine and Adenine Nucleotides in the Biological System. Edited by S Imai, M Nakazawa. Amsterdam, Elsevier Science Publishers BV, 1991, pp 43-55
50. Jarvis SM, Williams TC, Doherty AJ, Griffith DA: Sodium-dependent nucleoside transport in epithelial cells. Role of Adenosine and Adenine Nucleotides in the Biological System. Edited by S Imai, M Nakazawa. Amsterdam, Elsevier Science Publishers BV, 1991, pp 151-160
51. Griffiths M, Beaumont N, Yao SYM, Sundaram M, Boumah CE, Davies A, Kwong FYP, Coe I, Cass CE, Young JD, Baldwin SA: Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med 1997, 3:89-93
52. Griffiths M, Yao SYM, Abidi F, Phillips SEV, Cass CE, Young JD, Baldwin SA: Molecular cloning and characterization of a nitrobenzyl-thioinosine- insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem J 1997, 328:739-743
53. Ward JL, Sherali A, Mo Z-P, Tse C-M: Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. J Biol Chem 2000, 275:8375-8381
54. +-independent transport systems in T84 and Caco-2 cells. Biochim Biophys Acta 1999, 1419:15-22
55. Kemperman H, Wijnands YM, Roos ED: aV integrins on HT-29 colon carcinoma cells: adhesion to fibronectin is mediated solely by small amounts of αVβ6, and αVβ5 is codistributed with actin fibers. Exp Cell Res 1997, 234:156-164
56. Chantret I, Barbat A, Dussaulx E, Brattain MG, Zweibaum A: Epithelial polarity, villin expression, and enterocytic differentiation of cultured human colon carcinoma cells: a survey of twenty cell lines. Cancer Res 1988, 48:1936-1942
57. Darmoul D, Lacasa M, Baricault L, Marguet D, Sapin C, Trotot P, Barbat A, Trugnan G: Dipeptidyl peptidase IV (CD26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation. J Biol Chem 1992, 267:4824-4833
58. Howell S, Kenny AJ, Turner AJ: A survey of membrane peptidases in two human colonic cell lines, Caco-2 and HT-29. Biochem J 1992, 284:595-601
59. Griffith DA, Jarvis SM: Nucleoside and nucleobase transport systems of mammalian cells. Biochim Biophys Acta 1996, 1286:153-181
60. Balkwill F: Chemokine biology in cancer. Semin Immunol 2003, 15: 49-55
61. Lambeir A-M, Proost P, Durinx C, Bal G, Senten K, Augustyns K, Scharpé S, Van Damme J, De Meester I: Kinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine family. J Biol Chem 2001, 32:29839-29845
62. Lambeir A-M, Proost P, Scharpé S, De Meester I: A kinetic study of glucagon-like peptide-1 and glucagon-like peptide-2 truncation by dipeptidyl peptidase IV, in vitro. Biochem Pharmacol 2002, 64:1753-1756
63. Dwinell MB, Eckman L, Leopard JD, Varki NM, Kagnoff MF: Chemokine receptor expression by human intestinal epithelial cells. Gastroenterology 1999, 117:359-367
64. Jordan NJ, Kolios G, Abbot SE, Sinai MA, Thompson DA, Petraki K, Westwick J: Expression of functional CXCR4 chemokine receptors on human colonic epithelial cells. J Clin Invest 1999, 104:1061-1069
65. Müller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN, Barrera JL, Mohar A, Verástegui E, Zlotnik A: Involvement of chemokine receptors in breast cancer metastasis. Nature (Lond) 2001, 410:50-56
66. Zeelenberg IS, Ruuls-Van Stalle L, Roos E: The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma metastases. Cancer Res 2003, 63:3833-3839
67. Leith JT, Padfield G, Faulkner L, Michelson S: Hypoxic fractions in xenografted human colon tumors. Cancer Res 1991, 51:5139-5143