메뉴 건너뛰기




Volumn 20, Issue 2, 2010, Pages 490-497

Loss of inhibitor of growth (ING-4) is implicated in the pathogenesis and progression of human astrocytomas

Author keywords

Human astrocytomas; ING 4; NF B

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SYNAPTOTAGMIN I; UROKINASE;

EID: 75949101066     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2009.00325.x     Document Type: Article
Times cited : (23)

References (45)
  • 1
    • 0028861418 scopus 로고
    • The PHD finger: Implications for chromatin-mediated transcriptional regulation
    • Aasland R, Gibson TJ, Stewart AF (1995) The PHD finger: implications for chromatin-mediated transcriptional regulation. Trends Biochem Sci 20 : 56 59.
    • (1995) Trends Biochem Sci , vol.20 , pp. 56-59
    • Aasland, R.1    Gibson, T.J.2    Stewart, A.F.3
  • 2
    • 0035174615 scopus 로고    scopus 로고
    • Series introduction: The transcription factor NF-kappaB and human disease
    • Baldwin AS Jr. (2001) Series introduction: the transcription factor NF-kappaB and human disease. J Clin Invest 107 : 3 6.
    • (2001) J Clin Invest , vol.107 , pp. 3-6
    • Baldwin, Jr.A.S.1
  • 3
    • 0029150795 scopus 로고
    • Proteolytic remodeling of extracellular matrix
    • Birkedal-Hansen H (1995) Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7 : 728 735.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 728-735
    • Birkedal-Hansen, H.1
  • 4
    • 19344366798 scopus 로고    scopus 로고
    • Gelatinase-mediated migration and invasion of cancer cells
    • Bjorklund M, Koivunen E (2005) Gelatinase-mediated migration and invasion of cancer cells. Biochim Biophys Acta 1755 : 37 69.
    • (2005) Biochim Biophys Acta , vol.1755 , pp. 37-69
    • Bjorklund, M.1    Koivunen, E.2
  • 5
    • 17844397949 scopus 로고    scopus 로고
    • The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
    • Brat DJ, Bellail AC, Van Meir EG (2005) The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro Oncol 7 : 122 133.
    • (2005) Neuro Oncol , vol.7 , pp. 122-133
    • Brat, D.J.1    Bellail, A.C.2    Van Meir, E.G.3
  • 6
    • 0027469921 scopus 로고
    • Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma
    • Brown PD, Bloxidge RE, Stuart NS, Gatter KC, Carmichael J (1993) Association between expression of activated 72-kilodalton gelatinase and tumor spread in non-small-cell lung carcinoma. J Natl Cancer Inst 85 : 574 578.
    • (1993) J Natl Cancer Inst , vol.85 , pp. 574-578
    • Brown, P.D.1    Bloxidge, R.E.2    Stuart, N.S.3    Gatter, K.C.4    Carmichael, J.5
  • 7
    • 9744270782 scopus 로고    scopus 로고
    • Biological functions of the ING family tumor suppressors
    • Campos EI, Chin MY, Kuo WH, Li G (2004) Biological functions of the ING family tumor suppressors. Cell Mol Life Sci 61 : 2597 2613.
    • (2004) Cell Mol Life Sci , vol.61 , pp. 2597-2613
    • Campos, E.I.1    Chin, M.Y.2    Kuo, W.H.3    Li, G.4
  • 8
    • 0036715324 scopus 로고    scopus 로고
    • Active matrix metalloproteinase 9 expression is associated with primary glioblastoma subtype
    • Choe G, Park JK, Jouben-Steele L, Kremen TJ, Liau LM, Vinters HV et al (2002) Active matrix metalloproteinase 9 expression is associated with primary glioblastoma subtype. Clin Cancer Res 8 : 2894 2901.
    • (2002) Clin Cancer Res , vol.8 , pp. 2894-2901
    • Choe, G.1    Park, J.K.2    Jouben-Steele, L.3    Kremen, T.J.4    Liau, L.M.5    Vinters, H.V.6
  • 9
    • 58149171661 scopus 로고    scopus 로고
    • The ING gene family in the regulation of cell growth and tumorigenesis
    • Coles AH, Jones SN (2009) The ING gene family in the regulation of cell growth and tumorigenesis. J Cell Physiol 218 : 45 57.
    • (2009) J Cell Physiol , vol.218 , pp. 45-57
    • Coles, A.H.1    Jones, S.N.2
  • 10
    • 39649104151 scopus 로고    scopus 로고
    • The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: Involvement in myeloma-induced angiogenesis
    • Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D et al (2007) The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis. Blood 110 : 4464 4475.
    • (2007) Blood , vol.110 , pp. 4464-4475
    • Colla, S.1    Tagliaferri, S.2    Morandi, F.3    Lunghi, P.4    Donofrio, G.5    Martorana, D.6
  • 11
    • 23044455714 scopus 로고    scopus 로고
    • Osteopontin: Its role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression
    • Das R, Philip S, Mahabeleshwar GH, Bulbule A, Kundu GC (2005) Osteopontin: its role in regulation of cell motility and nuclear factor kappa B-mediated urokinase type plasminogen activator expression. IUBMB Life 57 : 441 447.
    • (2005) IUBMB Life , vol.57 , pp. 441-447
    • Das, R.1    Philip, S.2    Mahabeleshwar, G.H.3    Bulbule, A.4    Kundu, G.C.5
  • 12
    • 0036850549 scopus 로고    scopus 로고
    • Different HATS of the ING1 gene family
    • Feng X, Hara Y, Riabowol K (2002) Different HATS of the ING1 gene family. Trends Cell Biol 12 : 532 538.
    • (2002) Trends Cell Biol , vol.12 , pp. 532-538
    • Feng, X.1    Hara, Y.2    Riabowol, K.3
  • 13
    • 1642586297 scopus 로고    scopus 로고
    • The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis
    • Garkavtsev I, Kozin SV, Chernova O, Xu L, Winkler F, Brown E et al (2004) The candidate tumour suppressor protein ING4 regulates brain tumour growth and angiogenesis. Nature 428 : 328 332.
    • (2004) Nature , vol.428 , pp. 328-332
    • Garkavtsev, I.1    Kozin, S.V.2    Chernova, O.3    Xu, L.4    Winkler, F.5    Brown, E.6
  • 14
    • 64549083733 scopus 로고    scopus 로고
    • Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases
    • Gondi CS, Rao JS (2009) Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases. Methods Mol Biol 487 : 267 281.
    • (2009) Methods Mol Biol , vol.487 , pp. 267-281
    • Gondi, C.S.1    Rao, J.S.2
  • 15
    • 23844441255 scopus 로고    scopus 로고
    • Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas
    • Gunduz M, Magatsuka H, Demiran K, Gunduz E, Cenqiz B, Ouchida M et al (2005) Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas. Gene 356 : 109 117.
    • (2005) Gene , vol.356 , pp. 109-117
    • Gunduz, M.1    Magatsuka, H.2    Demiran, K.3    Gunduz, E.4    Cenqiz, B.5    Ouchida, M.6
  • 16
    • 45849089123 scopus 로고    scopus 로고
    • The inhibitor of growth (ING) gene family: Potential role in cancer therapy
    • Gunduz M, Gunduz E, Rivera RS, Nagatsuka H (2008) The inhibitor of growth (ING) gene family: potential role in cancer therapy. Curr Cancer Drug Targets 8 : 275 284.
    • (2008) Curr Cancer Drug Targets , vol.8 , pp. 275-284
    • Gunduz, M.1    Gunduz, E.2    Rivera, R.S.3    Nagatsuka, H.4
  • 17
    • 0035156633 scopus 로고    scopus 로고
    • F-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP
    • Han YP, Tuan TL, Wu H, Hughes M, Garner WLTN (2001) F-alpha stimulates activation of pro-MMP2 in human skin through NF-(kappa)B mediated induction of MT1-MMP. J Cell Sci 114 : 131 139.
    • (2001) J Cell Sci , vol.114 , pp. 131-139
    • Han, Y.P.1    Tuan, T.L.2    Wu, H.3    Hughes, M.4    Wltn, G.5
  • 18
    • 0035849720 scopus 로고    scopus 로고
    • Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis
    • Huang S, Pettaway CA, Uehara H, Bucana CD, Fidler IJ (2001) Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene 20 : 4188 4197.
    • (2001) Oncogene , vol.20 , pp. 4188-4197
    • Huang, S.1    Pettaway, C.A.2    Uehara, H.3    Bucana, C.D.4    Fidler, I.J.5
  • 19
    • 0024428950 scopus 로고
    • Urokinase-type plasminogen activator antigen and early relapse in breast cancer
    • Janicke F, Schmitt M, Ulm K, Gossner W, Graeff H (1989) Urokinase-type plasminogen activator antigen and early relapse in breast cancer. Lancet 2 : 1049.
    • (1989) Lancet , vol.2 , pp. 1049
    • Janicke, F.1    Schmitt, M.2    Ulm, K.3    Gossner, W.4    Graeff, H.5
  • 20
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim HJ, Hawke N, Baldwin AS (2006) NF-kappaB and IKK as therapeutic targets in cancer. Cell Death Differ 13 : 738 747.
    • (2006) Cell Death Differ , vol.13 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 21
    • 9244239717 scopus 로고    scopus 로고
    • A screen for genes that suppress loss of contact inhibition: Identification of ING4 as a candidate tumor suppressor gene in human cancer
    • Kim S, Chin K, Gray JW, Bishop JM (2004) A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer. Proc Natl Acad Sci USA 101 : 16251 16256.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16251-16256
    • Kim, S.1    Chin, K.2    Gray, J.W.3    Bishop, J.M.4
  • 22
    • 34248178375 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer
    • Kong D, Li Y, Wang Z, Banerjee S, Sarkar FH (2007) Inhibition of angiogenesis and invasion by 3,3′-diindolylmethane is mediated by the nuclear factor-kappaB downstream target genes MMP-9 and uPA that regulated bioavailability of vascular endothelial growth factor in prostate cancer. Cancer Res 67 : 3310 3319.
    • (2007) Cancer Res , vol.67 , pp. 3310-3319
    • Kong, D.1    Li, Y.2    Wang, Z.3    Banerjee, S.4    Sarkar, F.H.5
  • 23
    • 47549114245 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB in human astrocytomas: Relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival
    • Korkolopoulou P, Levidou G, Saetta AA, Habr EI, Eftichiadis C, Demenagas P et al (2008) Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival. Hum Pathol 39 : 1143 1152.
    • (2008) Hum Pathol , vol.39 , pp. 1143-1152
    • Korkolopoulou, P.1    Levidou, G.2    Saetta, A.A.3    Habr, E.I.4    Eftichiadis, C.5    Demenagas, P.6
  • 24
    • 34250898562 scopus 로고    scopus 로고
    • NF-kappaB as a potential molecular target for cancer therapy
    • Lee CH, Jeon YT, Kim SH, Song YS (2007) NF-kappaB as a potential molecular target for cancer therapy. Biofactors 29 : 19 35.
    • (2007) Biofactors , vol.29 , pp. 19-35
    • Lee, C.H.1    Jeon, Y.T.2    Kim, S.H.3    Song, Y.S.4
  • 25
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • Lefranc F, Brotchi J, Kiss R (2005) Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol 23 : 2411 2422.
    • (2005) J Clin Oncol , vol.23 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 26
    • 49349105425 scopus 로고    scopus 로고
    • Role of ING4 in human melanoma cell migration, invasion and patient survival
    • Li J, Martinka M, Li G (2008) Role of ING4 in human melanoma cell migration, invasion and patient survival. Carcinogenesis 29 : 1373 1379.
    • (2008) Carcinogenesis , vol.29 , pp. 1373-1379
    • Li, J.1    Martinka, M.2    Li, G.3
  • 27
    • 0037780982 scopus 로고    scopus 로고
    • Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer
    • Liptay S, Weber CK, Ludwig L, Wagner M, Adler G, Schmid RM et al (2003) Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer. Int J Cancer 105 : 735 746.
    • (2003) Int J Cancer , vol.105 , pp. 735-746
    • Liptay, S.1    Weber, C.K.2    Ludwig, L.3    Wagner, M.4    Adler, G.5    Schmid, R.M.6
  • 29
    • 0027535914 scopus 로고
    • Biology and biochemistry of proteinases in tumor invasion
    • Mignatti P, Rifkin DB (1993) Biology and biochemistry of proteinases in tumor invasion. Physiol Rev 73 : 161 195.
    • (1993) Physiol Rev , vol.73 , pp. 161-195
    • Mignatti, P.1    Rifkin, D.B.2
  • 30
    • 4444304939 scopus 로고    scopus 로고
    • Regulation of matrix biology by matrix metalloproteinases
    • Mott JD, Werb Z (2004) Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol 16 : 558 564.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 558-564
    • Mott, J.D.1    Werb, Z.2
  • 32
    • 0025899613 scopus 로고
    • A labile repressor acts through the NFkB-like binding sites of the human urokinase gene
    • Novak U, Cocks BG, Hamilton JA (1991) A labile repressor acts through the NFkB-like binding sites of the human urokinase gene. Nucleic Acids Res 19 : 3389 3393.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3389-3393
    • Novak, U.1    Cocks, B.G.2    Hamilton, J.A.3
  • 33
    • 0442323562 scopus 로고    scopus 로고
    • NF-kappaB tumor promoter or suppressor?
    • Perkins ND (2004) NF-kappaB tumor promoter or suppressor? Trends Cell Biol 14 : 64 69.
    • (2004) Trends Cell Biol , vol.14 , pp. 64-69
    • Perkins, N.D.1
  • 35
    • 0041737535 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma invasiveness: The role of proteases
    • Rao JS (2003) Molecular mechanisms of glioma invasiveness: the role of proteases. Nat Rev Cancer 3 : 489 501.
    • (2003) Nat Rev Cancer , vol.3 , pp. 489-501
    • Rao, J.S.1
  • 36
    • 34548799835 scopus 로고    scopus 로고
    • Aberrant constitutive activation of nuclear factor kappaB in glioblastoma multiforme drives invasive phenotype
    • Raychaudhuri B, Han Y, Lu T, Vogelbaum MA (2007) Aberrant constitutive activation of nuclear factor kappaB in glioblastoma multiforme drives invasive phenotype. J Neurooncol 85 : 39 47.
    • (2007) J Neurooncol , vol.85 , pp. 39-47
    • Raychaudhuri, B.1    Han, Y.2    Lu, T.3    Vogelbaum, M.A.4
  • 37
    • 0028970647 scopus 로고
    • Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1
    • Reuning U, Wilhelm O, Nishiguchi T, Guerrini L, Blasi F, Graeff H et al (1995) Inhibition of NF-kappa B-Rel A expression by antisense oligodeoxynucleotides suppresses synthesis of urokinase-type plasminogen activator (uPA) but not its inhibitor PAI-1. Nucleic Acids Res 23 : 3887 3893.
    • (1995) Nucleic Acids Res , vol.23 , pp. 3887-3893
    • Reuning, U.1    Wilhelm, O.2    Nishiguchi, T.3    Guerrini, L.4    Blasi, F.5    Graeff, H.6
  • 38
    • 0023236992 scopus 로고
    • Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas
    • Sappino AP, Busso N, Belin D, Vassalli JD (1987) Increase of urokinase-type plasminogen activator gene expression in human lung and breast carcinomas. Cancer Res 47 : 4043 4046.
    • (1987) Cancer Res , vol.47 , pp. 4043-4046
    • Sappino, A.P.1    Busso, N.2    Belin, D.3    Vassalli, J.D.4
  • 39
    • 0026019020 scopus 로고
    • Biological significance of tissue plasminogen activator content in brain tumors
    • Sawaya R, Ramo OJ, Shi ML, Mandybur G (1991) Biological significance of tissue plasminogen activator content in brain tumors. J Neurosurg 74 : 480 486.
    • (1991) J Neurosurg , vol.74 , pp. 480-486
    • Sawaya, R.1    Ramo, O.J.2    Shi, M.L.3    Mandybur, G.4
  • 40
    • 2942717090 scopus 로고    scopus 로고
    • Signaling pathways responsible for cancer cell invasion as targets for cancer therapy
    • Sliva D (2004) Signaling pathways responsible for cancer cell invasion as targets for cancer therapy. Curr Cancer Drug Targets 4 : 327 336.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 327-336
    • Sliva, D.1
  • 41
    • 0242266487 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma
    • DOI 10.1038/sj.bjc.6601238
    • Talvensaari-Mattila A, Paakko P, Turpeenniemi-Hujanen T (2003) Matrix metalloproteinase-2 (MMP-2) is associated with survival in breast carcinoma. Br J Cancer 89 : 1270 1275. (Pubitemid 37363416)
    • (2003) British Journal of Cancer , vol.89 , Issue.7 , pp. 1270-1275
    • Talvensaari-Mattila, A.1    Paakko, P.2    Turpeenniemi-Hujanen, T.3
  • 42
    • 33845938807 scopus 로고    scopus 로고
    • Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility
    • Unoki M, Shen JC, Zheng ZM, Harris CC (2006) Novel splice variants of ING4 and their possible roles in the regulation of cell growth and motility. J Biol Chem 281 : 34677 34686.
    • (2006) J Biol Chem , vol.281 , pp. 34677-34686
    • Unoki, M.1    Shen, J.C.2    Zheng, Z.M.3    Harris, C.C.4
  • 43
    • 0031596140 scopus 로고    scopus 로고
    • Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts
    • Vincenti MP, Coon CI, Brinckerhoff CE (1998) Nuclear factor kappaB/p50 activates an element in the distal matrix metalloproteinase 1 promoter in interleukin-1beta-stimulated synovial fibroblasts. Arthritis Rheum 41 : 1987 1994.
    • (1998) Arthritis Rheum , vol.41 , pp. 1987-1994
    • Vincenti, M.P.1    Coon, C.I.2    Brinckerhoff, C.E.3
  • 44
    • 0033549875 scopus 로고    scopus 로고
    • Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA
    • Wang W, Abbruzzese JL, Evans DB, Chiao PJ (1999) Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. Oncogene 18 : 4554 4563.
    • (1999) Oncogene , vol.18 , pp. 4554-4563
    • Wang, W.1    Abbruzzese, J.L.2    Evans, D.B.3    Chiao, P.J.4
  • 45
    • 64649087510 scopus 로고    scopus 로고
    • NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy
    • Wu JM, Sheng H, Saxena R, Skill NJ, Bhat-Nakshatri P, Yu M et al (2009) NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy. Cancer Lett 278 : 145 155.
    • (2009) Cancer Lett , vol.278 , pp. 145-155
    • Wu, J.M.1    Sheng, H.2    Saxena, R.3    Skill, N.J.4    Bhat-Nakshatri, P.5    Yu, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.