New therapies for non-muscle-invasive bladder cancer

World Journal of Urology

Volumn 28, Issue 1, 2010, Pages 71-78

  Chiong, Edmund ^a,b   Esuvaranathan, Kesavan ^a,b  

^a NATIONAL UNIVERSITY HOSPITAL   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Bladder cancer; Chemotherapy; Gene therapy; Immunotherapy; Intravesical administration

Indexed keywords

ANTINEOPLASTIC AGENT;

BLADDER TUMOR; DRUG DELIVERY SYSTEM; GENE THERAPY; HUMAN; IMMUNOTHERAPY; REVIEW;

ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; GENE THERAPY; HUMANS; IMMUNOTHERAPY; URINARY BLADDER NEOPLASMS;

EID: 75849125165     PISSN: 07244983     EISSN: 14338726     Source Type: Journal    
DOI: 10.1007/s00345-009-0474-1     Document Type: Review

References (60)

1. Heney NM, Ahmed S, Flanagan MJ, Frable W, Corder MP, Hafermann MD et al (1983) Superficial bladder cancer: progression and recurrence. J Urol 130: 1083-1086.
2. Botteman MF, Pashos CL, Redaelli A, Laskin B, Hauser R (2003) The health economics of bladder cancer: a comprehensive review of the published literature. Pharmacoeconomics 21: 1315-1330.
3. Sylvester RJ, van der Meijden APM, Lamm DL (2002) Intravesical bacillus Calmette-Guerin reduces the risk of progression in patients with superficial bladder cancer: a meta-analysis of the published results of randomized clinical trials. J Urol 168: 1964-1970.
4. Witjes JA (2006) Management of BCG failures in superficial bladder cancer: a review. Eur Urol 49(5): 790-797.
5. Lamm D, Riggs D, Traynelis C, Nseyo U (1995) Apparent failure of current intravesical chemotherapy prophylaxis to influence the long-term course of superficial transitional cell carcinoma of the bladder. J Urol 153: 1444-1450.
6. Morales A (2008) Evolution of intravesical immunotherapy for bladder cancer: mycobacterial cell wall preparation as a promising agent. Expert Opin Investig Drugs 17(7): 1067-1073.
7. Morales A, Chin J, Ramsey EW (2001) Mycobacterial cell wall extract in the treatment of carcinoma in situ of the bladder. J Urol 166: 1633-1636.
8. Takahashi T, Kushiro A, Nomoto K, Uchida K, Morotomi M, Yokokura T et al (2001) Antitumor effects of the intravesical instillation of heat killed cells of the Lactobacillus casei strain Shirota on the murine orthotopic bladder tumor MBT-2. J Urol 166: 2506.
9. Seow SW, Rahmat JN, Mohamed AA, Mahendran R, Lee YK, Bay BH (2002) Lactobacillus species is more cytotoxic to human bladder cancer cells than Mycobacterium Bovis (bacillus Calmette-Guerin). J Urol 168(5): 2236-2239.
10. Naito S, Koga H, Yamaguchi A, Fujimoto N, Hasui Y, Kuramoto H et al (2008) Prevention of recurrence with epirubicin and lactobacillus casei after transurethral resection of bladder cancer. J Urol 179: 485-490.
11. Nepple KG, Aubert HA, Braasch MR, O'Donnell MA (2009) Combination of BCG and interferon intravesical immunotherapy: an update. World J Urol 27(3): 343-346.
12. Joudi FN, Smith BJ, O'Donnell MA, National BCG-Interferon Phase 2 Investigator Group (2006) Final results from a national multicenter phase II trial of combination bacillus Calmette-Guérin plus interferon alpha-2B for reducing recurrence of superficial bladder cancer. Urol Oncol 24(4): 344-348.
13. Esuvaranathan K, Cheng WS, Chia SJ, Ng FC, Mahendran R, The Bladder Cancer Workgroup (2004). A five-year data of a randomized controlled trial of standard dose BCG versus low dose BCG and interferon alpha in patients with superficial bladder cancer. J Urol (Suppl) 171(4): 73 (Abstract).
14. Lee CF, Chang SY, Hsieh DS, Yu DS (2004) Immunotherapy for bladder cancer using recombinant bacillus Calmette-Guerin DNA vaccines and interleukin-12 DNA vaccine. J Urol 171(3): 1343-1347.
15. Dalbagni G, Russo P, Sheinfeld J, Mazumdar M, Tong W, Rabbani F et al (2002) Phase I trial of intravesical gemcitabine in bacillus Calmette-Guerin-refractory transitional-cell carcinoma of the bladder. J Clin Oncol 20: 3193-3198.
16. Laufer M, Ramalingam S, Schoenberg MP, Haisfield-Wolf ME, Zuhowski EG, Trueheart IN et al (2003) Intravesical gemcitabine therapy for superficial transitional cell carcinoma of the bladder: a phase I and pharmacokinetic study. J Clin Oncol 21: 697-703.
17. Witjes JA, van der Heijden AG, Vriesema JL, Peters GJ, Laan A, Schalken JA (2004) Intravesical gemcitabine: a phase 1 and pharmacokinetic study. Eur Urol 45: 182-186.
18. De Berardinis E, Antonini G, Peters GJ, Loves WJ, van Der Born K, Codacci-Pisanelli G et al (2004) Intravesical administration of gemcitabine in superficial bladder cancer: a phase I study with pharmacodynamic evaluation. BJU Int 93: 491-494.
19. Gontero P, Casetta G, Maso G, Sogni F, Pretti G, Zitella A et al (2004) Phase II study to investigate the ablative efficacy of intravesical administration of gemcitabine in intermediate-risk superficial bladder cancer (SBC). Eur Urol 46: 339-343.
20. Serretta V, Galuffo A, Pavone C, Allegro R, Pavone-MacAluso M (2005) Gemcitabine in intravesical treatment of Ta-T1 transitional cell carcinoma of bladder: phase I-II study on marker lesions. Urology 65: 65-69.
21. Dalbagni G, Russo P, Sheinfeld J, Mazumdar M, Tong W, Rabbani F et al (2002) Phase I trial of intravesical gemcitabine in bacillus Calmette-Guérin-refractory transitional-cell carcinoma of the bladder. J Clin Oncol 20(15): 3193-3198.
22. Rangel C, Niell H, Miller A, Cox C (1994) Taxol and taxotere in bladder cancer: in vitro activity and urine stability. Cancer Chemother Pharmacol 33: 460-464.
23. Nativ O, Aronson M, Medalia O, Moldavsky T, Sabo E, Ringel I et al (1997) Anti-neoplastic activity of paclitaxel on experimental superficial bladder cancer: in vivo and in vitro studies. Int J Cancer 70: 297-301.
24. McKiernan JM, Masson P, Murphy AM, Goetzl M, Olsson CA, Petrylak DP et al (2006) Phase I trial of intravesical docetaxel in the management of superficial bladder cancer refractory to standard intravesical therapy. J Clin Oncol 24(19): 3075-3080.
25. Le Visage C, Rioux-Leclercq N, Haller M, Breton P, Malavaud B, Leong K (2004) Efficacy of paclitaxel released from bio-adhesive polymer microspheres on model superficial bladder cancer. J Urol 171: 1324-1329.
26. Lu Z, Yeh TK, Tsai M, Au JL, Wientjes MG (2004) Paclitaxel-loaded gelatin nanoparticles for intravesical bladder cancer therapy. Clin Cancer Res 10(22): 7677-7684.
27. Mugabe C, Hadaschik BA, Kainthan RK, Brooks DE, So AI, Gleave ME et al (2008) Paclitaxel incorporated in hydrophobically derivatized hyperbranched polyglycerols for intravesical bladder cancer therapy. BJU Int 103: 978-986 (Epub ahead of print).
28. Walther MM, Figg WD, Linehan WM (1996) Intravesical suramin: a novel agent for the treatment of superficial transitional-cell carcinoma of the bladder. World J Urol 14(Suppl 1): 8-11.
29. Xin Y, Lyness G, Chen D, Song S, Wientjes MG, Au JL (2005) Low dose suramin as a chemosensitizer of bladder cancer to mitomycin C. J Urol 174(1): 322-327.
30. Ord JJ, Streeter E, Jones A, Le Monnier K, Cranston D, Crew J et al (2005) Phase I trial of intravesical suramin in recurrent superficial transitional cell bladder carcinoma. Br J Cancer 92: 2140-2147.
31. Uchio EM, Linehan WM, Figg WD, Walther MM (2003) A phase I study of intravesical suramin for the treatment of superficial transitional cell carcinoma of the bladder. J Urol 169: 357-360.
32. Harris NM, Anderson WR, Lwaleed BA, Cooper AJ, Birch BR, Solomon LZ (2003) Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. Cancer 97(1): 71-78.
33. Crook T, Hall S, Solomon L, Bass P, Cooper A, Birch B (2000) Intravesical meglumine gamma-linolenic acid. Phase I tolerability study in patients undergoing cystectomy. UroOncology 1: 39-42.
34. Harris NM, Crook TJ, Dyer JP, Solomon LZ, Bass P, Cooper AJ et al (2002) Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. Eur Urol 42(1): 39-42.
35. van der Heijden AG, Moonen PM, Cornel EB, Vergunst H, de Reijke TM, van Boven E et al (2006) Phase II marker lesion study with intravesical instillation of apaziquone for superficial bladder cancer: toxicity and marker response. J Urol 176: 1349-1353.
36. Li D, Gan Y, Wientjes MG, Badalament RA, Au JL (2001) Distribution of DT-diaphorase and reduced nicotinamide adenine dinucleotide phosphate: cytochrome p450 oxidoreductase in bladder tissues and tumors. J Urol 166: 2500-2505.
37. van der Heijden AG, Verhaegh G, Jansen CF, Schalken JA, Witjes JA (2005) Effect of hyperthermia on the cytotoxicity of 4 chemotherapeutic agents currently used for the treatment of transitional cell carcinoma of the bladder: an in vitro study. J Urol 173: 1375-1380.
38. Colombo R, Da Pozzo LF, Salonia A, Rigatti P, Leib Z, Baniel J et al (2003) Multicentric study comparing intravesical chemotherapy alone and with local microwave hyperthermia for prophylaxis of recurrence of superficial transitional cell carcinoma. J Clin Oncol 21: 4270-4276.
39. Gofrit ON, Shapiro A, Pode D, Sidi A, Nativ O, Leib Z et al (2004) Combined local bladder hyperthermia and intravesical chemotherapy for treatment of high-grade superficial bladder cancer. Urology 63: 466-471.
40. van der Heijden AG, Kiemeney LA, Gofrit ON, Nativ O, Sidi A, Leib Z et al (2004) Preliminary European results of local microwave hyperthermia and chemotherapy treatment in intermediate or high risk superficial transitional cell carcinoma of the bladder. Eur Urol 46: 65-72.
41. Witjes JA, Hendricksen K, Gofrit O, Risi O, Nativ O (2007) Intravesical hyperthermia and mitomycin-C for (BCG refractory) carcinoma in situ of the urinary bladder. Eur Urol Suppl 6: 60 (Abstract).
42. Colombo R, Brausi M, Da Pozzo L, Salonia A, Montorsi F, Scattoni V et al (2001) Thermo-chemotherapy and electromotive drug administration of mitomycin C in superficial bladder cancer eradication, a pilot study on marker lesion. Eur Urol 39: 95-100.
43. Di Stasi SM, Giannantoni A, Stephen RL, Capelli G, Navarra P, Massoud R et al (2003) Intravesical electromotive mitomycin C versus passive transport mitomycin C for high risk superficial bladder cancer: a prospective randomized study. J Urol 170: 777-782.
44. Di Stasi SM, Giannantoni A, Giurioli A, Valenti M, Zampa G, Storti L et al (2006) Sequential BCG and electromotive mitomycin versus BCG alone for high-risk superficial bladder cancer: a randomised controlled trial. Lancet Oncol 7: 43-51.
45. Berger AP, Steiner H, Stenzl A, Akkad T, Bartsch G, Holtl L (2003) Photodynamic therapy with intravesical instillation of 5-aminolevulinic acid for patients with recurrent superficial bladder cancer: a single-center study. Urology 61: 338-341.
46. Manyak MJ, Ogan K (2003) Photodynamic therapy for refractory superficial bladder cancer: long-term clinical outcomes of single treatment using intravesical diffusion medium. J Endourol 17: 633-639.
47. Kamuhabwa AA, Roskams T, D'Hallewin MA, Baert L, van Poppel H, de Witte PA (2003) Whole bladder wall photodynamic therapy of transitional cell carcinoma rat bladder tumors using intravesically administered hypericin. Int J Cancer 107: 460-467.
48. Asanuma H, Arai T, Morimoto Y, Kawauchi S, Satoh H, Seguchi K et al (2005) Photodynamic therapy with PAD-S31, a new hydrophilic chlorin photosensitizer, in an orthotopic rat bladder tumor model. J Urol 174: 2016-2021.
49. Leakakos T, Ji C, Lawson G, Peterson C, Goodwin S (2003) Intravesical administration of doxorubicin to swine bladder using magnetically targeted carriers. Cancer Chemother Pharmacol 51(6): 445-450.
50. Miyake H, Hara I, Fujisaw M, Gleave ME (2005) Antisense oligodeoxynucleotide therapy for bladder cancer: recent advances and future prospects. Expert Rev Anticancer Ther 5(6): 1001-1009.
51. Fuessel S, Meye A, Kraemer K, Kunze D, Hakenberg OW, Wirth MP (2007) Synthetic nucleic acids as potential therapeutic tools for treatment of bladder carcinoma. Eur Urol 51(2): 315-326.
52. Kunze D, Wuttig D, Kausch I, Blietz C, Blumhoff L, Burmeister Y et al (2008) Antisense-mediated inhibition of survivin, hTERT and VEGF in bladder cancer cells in vitro and in vivo. Int J Oncol 32(5): 1049-1056.
53. Kamada M, So A, Muramaki M, Rocchi P, Beraldi E, Gleave M (2007) Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells. Mol Cancer Ther 6(1): 299-308.
54. Bolenz C, Becker A, Trojan L, Schaaf A, Cao Y, Weiss C et al (2007) Optimizing chemotherapy for transitional cell carcinoma by application of bcl-2 and bcl-xL antisense oligodeoxynucleotides. Urol Oncol 25(6): 476-482.
55. Loskog AS, Fransson ME, Totterman TT (2005) AdCD40L gene therapy counteracts T regulatory cells and cures aggressive tumors in an orthotopic bladder cancer model. Clin Cancer Res 11(24 Pt 1): 8816-8821.
56. Connor RJ, Anderson JM, Machemer T, Maneval DC, Engler H (2005) Sustained intravesical interferon protein exposure is achieved using an adenoviral-mediated gene delivery system: a study in rats evaluating dosing regimens. Urology 66(1): 224-229.
57. Tao Z, Connor RJ, Ashoori F, Dinney CP, Munsell M, Philopena JA et al (2006) Efficacy of a single intravesical treatment with Ad-IFN/Syn 3 is dependent on dose and urine IFN concentration obtained: implications for clinical investigation. Cancer Gene Ther 13(2): 125-130.
58. Wu Q, Mahendran R, Esuvaranathan K (2003) Nonviral cytokine gene therapy on an orthotopic bladder cancer model. Clin Cancer Res 9(12): 4522-4528.
59. Nogawa M, Yuasa T, Kimura S, Tanaka M, Kuroda J, Sato K et al (2005) Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer. J Clin Invest 115(4): 978-985.
60. Sidi AA, Ohana P, Benjamin S, Shalev M, Ransom JH, Lamm D et al (2008) Phase I/II marker lesion study of intravesical BC-819 DNA plasmid in H19 over expressing superficial bladder cancer refractory to bacillus Calmette-Guerin. J Urol 180(6): 2379-2383.