-
1
-
-
41349099104
-
Cancer statistics, 2008
-
10.3322/CA.2007.0010 18287387
-
A Jemal R Siegel E Ward Y Hao J Xu T Murray MJ Thun 2008 Cancer statistics, 2008 CA Cancer J Clin 58 71 96 10.3322/CA.2007.0010 18287387
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
Thun, M.J.7
-
2
-
-
42249094731
-
Pharmaceutical management of ovarian cancer: Current status
-
DOI 10.2165/00003495-200868060-00004
-
M Markman 2008 Pharmaceutical management of ovarian cancer: current status Drugs 68 771 789 10.2165/00003495-200868060-00004 1:CAS:528: DC%2BD1cXmvVeltL4%3D 18416585 (Pubitemid 351550530)
-
(2008)
Drugs
, vol.68
, Issue.6
, pp. 771-789
-
-
Markman, M.1
-
3
-
-
40849139532
-
Second-line randomized trials in epithelial ovarian cancer
-
10.1111/j.1525-1438.2007.01161.x 18336403
-
JB Vermorken 2008 Second-line randomized trials in epithelial ovarian cancer Int J Gynecol Cancer 18 Suppl 1 59 66 10.1111/j.1525-1438.2007.01161.x 18336403
-
(2008)
Int J Gynecol Cancer
, vol.18
, Issue.SUPPL 1
, pp. 59-66
-
-
Vermorken, J.B.1
-
4
-
-
1242339607
-
Optimal therapy of advanced ovarian cancer: Carboplatin and paclitaxel vs. cisplatin and paclitaxel (GOG 158) and an update on GOG0182-ICON5
-
DOI 10.1111/j.1525-1438.2003.13602.x
-
MA Bookman BE Greer RF Ozols 2003 Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel vs cisplatin and paclitaxel (GOG158) and an update on GOG 182-ICON5 Int J Gynecol Cancer 13 735 740 10.1111/j.1525-1438. 2003.13602.x 1:STN:280:DC%2BD3srpsVCjsg%3D%3D 14675308 (Pubitemid 38235216)
-
(2003)
International Journal of Gynecological Cancer
, vol.13
, Issue.6
, pp. 735-740
-
-
Bookman, M.A.1
Greer, B.E.2
Ozols, R.F.3
-
5
-
-
0037339485
-
Phase II study of gemcitabine in recurrent platinum-and paclitaxel-resistant ovarian cancer
-
DOI 10.1016/S0090-8258(03)00011-8
-
G D'Agostino F Amant P Berteloot G Scambia I Vergote 2003 Phase II study of gemcitabine in recurrent platinum- and paclitaxel resistant ovarian cancer Gynecol Oncol 88 266 269 10.1016/S0090-8258(03)00011-8 12648573 (Pubitemid 36331977)
-
(2003)
Gynecologic Oncology
, vol.88
, Issue.3
, pp. 266-269
-
-
D'Agostino, G.1
Amant, F.2
Berteloot, P.3
Scambia, G.4
Vergote, I.5
-
6
-
-
22644432004
-
Gemcitabine and liposomal doxorubicin in the salvage treatment of ovarian cancer: Updated results and long-term survival
-
DOI 10.1016/j.ygyno.2005.04.018, PII S0090825805003173
-
G Ferrandina I Paris M Ludovisi G D'Agostino A Testa D Lorusso M Zanghi S Pisconti G Pezzella V Adamo E Breda G Scambia 2005 Gemcitabine and liposomal doxorubicin in the salvage treatment of ovarian cancer: updated results and long-term survival Gynecol Oncol 98 267 273 10.1016/j.ygyno.2005.04.018 1:CAS:528:DC%2BD2MXmsVWgtbY%3D 15975643 (Pubitemid 41024849)
-
(2005)
Gynecologic Oncology
, vol.98
, Issue.2
, pp. 267-273
-
-
Ferrandina, G.1
Paris, I.2
Ludovisi, M.3
D'Agostino, G.4
Testa, A.5
Lorusso, D.6
Zanghi, M.7
Pisconti, S.8
Pezzella, G.9
Adamo, V.10
Breda, E.11
Scambia, G.12
-
7
-
-
35848960127
-
Review of recent studies on resistance to cytotoxic deoxynucleoside analogues
-
1:CAS:528:DC%2BD2sXht12hsLzM 17881132
-
LP Jordheim C Dumontet 2007 Review of recent studies on resistance to cytotoxic deoxynucleoside analogues Biochim Biophys Acta 1776 138 159 1:CAS:528:DC%2BD2sXht12hsLzM 17881132
-
(2007)
Biochim Biophys Acta
, vol.1776
, pp. 138-159
-
-
Jordheim, L.P.1
Dumontet, C.2
-
8
-
-
40949143108
-
Gemcitabine resistance in pancreatic cancer: Picking the key players
-
10.1158/1078-0432.CCR-07-2247 1:CAS:528:DC%2BD1cXislSku7k%3D 18316544
-
MP Kim GE Gallick 2008 Gemcitabine resistance in pancreatic cancer: picking the key players Clin Cancer Res 14 1284 1285 10.1158/1078-0432.CCR-07- 2247 1:CAS:528:DC%2BD1cXislSku7k%3D 18316544
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1284-1285
-
-
Kim, M.P.1
Gallick, G.E.2
-
9
-
-
46649083576
-
Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer
-
10.1016/j.bcp.2008.05.011 18589402
-
S Pérez-Torras J García-Manteiga E Mercadé FJ Casado N Carbó M Pastor-Anglada A Mazo 2008 Adenoviral-mediated overexpression of human equilibrative nucleoside transporter 1 (hENT1) enhances gemcitabine response in human pancreatic cancer Biochem Pharmacol 76 322 329 10.1016/j.bcp.2008.05.011 18589402
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 322-329
-
-
Pérez-Torras, S.1
García-Manteiga, J.2
Mercadé, E.3
Casado, F.J.4
Carbó, N.5
Pastor-Anglada, M.6
Mazo, A.7
-
10
-
-
0030720867
-
The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments
-
10.1073/pnas.94.24.13181
-
H Fan A Huang C Villegas JA Wright 1998 The R1 component of mammalian ribonucleotide reductase has malignancy-suppressing activity as demonstrated by gene transfer experiments Proc Natl Acad Sci USA 94 13181 13186 10.1073/pnas.94.24.13181
-
(1998)
Proc Natl Acad Sci USA
, vol.94
, pp. 13181-13186
-
-
Fan, H.1
Huang, A.2
Villegas, C.3
Wright, J.A.4
-
11
-
-
0038636459
-
RRM1-induced metastasis suppression through PTEN-regulated pathways
-
DOI 10.1038/sj.onc.1206232
-
A Gautam ZR Li G Begler 2003 RRM1-induced metastasis suppression through PTEN-regulated pathways Oncogene 22 2135 2142 10.1038/sj.onc.1206232 1:CAS:528:DC%2BD3sXislyitbo%3D 12687015 (Pubitemid 36539563)
-
(2003)
Oncogene
, vol.22
, Issue.14
, pp. 2135-2142
-
-
Gautam, A.1
Li, Z.-R.2
Bepler, G.3
-
12
-
-
0032522647
-
The mammalian ribonucleotide reductase R2 component cooperates with a variety of oncogenes in mechanisms of cellular transformation
-
1:CAS:528:DyaK1cXislertbo%3D 9563477
-
H Fan C Villegas A Huang JA Wright 1998 The mammalian ribonucleotide reductase R2 component cooperates with a variety of oncogenes in mechanisms of cellular transformation Cancer Res 58 1650 1653 1:CAS:528:DyaK1cXislertbo%3D 9563477
-
(1998)
Cancer Res
, vol.58
, pp. 1650-1653
-
-
Fan, H.1
Villegas, C.2
Huang, A.3
Wright, J.A.4
-
13
-
-
0031938457
-
Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential
-
DOI 10.1023/A:1006559901771
-
BS Zhou R Tsai R Ker J Tsai R Ho J Yu J Shih Y Yen 1998 Overexpression of the transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential Exp Clin Met 16 43 49 10.1023/A:1006559901771 1:CAS:528:DyaK1cXhvVyitL8%3D (Pubitemid 28122554)
-
(1998)
Clinical and Experimental Metastasis
, vol.16
, Issue.1
, pp. 43-49
-
-
Zhou, B.-S.1
Tsai, P.2
Ker, R.3
Tsai, J.4
Ho, R.5
Yu, J.6
Shih, J.7
Yen, Y.8
-
14
-
-
33846296549
-
RRM2 induces NF-κB-dependent MMP-9 activation and enhances cellular invasiveness
-
DOI 10.1016/j.bbrc.2006.12.177, PII S0006291X06028567
-
MS Duxbury EE Whang 2007 RRM2 induces NF-κB-dependent MMP-9 activation and enhances cellular invasiveness Biochem Biophys Res Commun 354 190 196 10.1016/j.bbrc.2006.12.177 1:CAS:528:DC%2BD2sXhtVCls7s%3D 17222798 (Pubitemid 46123218)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.354
, Issue.1
, pp. 190-196
-
-
Duxbury, M.S.1
Whang, E.E.2
-
15
-
-
33645731188
-
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine
-
10.1158/0008-5472.CAN-05-4203 1:CAS:528:DC%2BD28XjtVOqs7k%3D 16585222
-
E Giovannetti M Del Tacca V Mey N Funel S Nannizzi S Ricci C Orlandini U Boggi D Campani M Del Chiaro M Iannopollo G Bevilacqua F Mosca R Danesi 2006 Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine Cancer Res 66 3928 3935 10.1158/0008-5472.CAN-05-4203 1:CAS:528:DC%2BD28XjtVOqs7k%3D 16585222
-
(2006)
Cancer Res
, vol.66
, pp. 3928-3935
-
-
Giovannetti, E.1
Del Tacca, M.2
Mey, V.3
Funel, N.4
Nannizzi, S.5
Ricci, S.6
Orlandini, C.7
Boggi, U.8
Campani, D.9
Del Chiaro, M.10
Iannopollo, M.11
Bevilacqua, G.12
Mosca, F.13
Danesi, R.14
-
16
-
-
33646407273
-
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: Relationship to molecular mechanisms of gemcitabine resistance and survival
-
10.1158/1078-0432.CCR-05-2655
-
V Sebastiani Sebastiani F Ricci B Rubio-Viqueira P Kulesza CJ Yeo M Hidalgo A Klein D Laheru CA Iacobuzio-Donahue 2006 Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival Clin Cancer Res 12 2492 2497 10.1158/1078-0432.CCR-05-2655
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2492-2497
-
-
Sebastiani Sebastiani, V.1
Ricci, F.2
Rubio-Viqueira, B.3
Kulesza, P.4
Yeo, C.J.5
Hidalgo, M.6
Klein, A.7
Laheru, D.8
Iacobuzio-Donahue, C.A.9
-
17
-
-
33746915066
-
In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients
-
DOI 10.1038/sj.bjc.6603242, PII 6603242
-
V Mey E Giovannetti F De Braud S Nannizzi G Curigliano De Verweij O Cobelli S Pece M Del Tacca R Danesi 2006 In vitro synergistic cytotoxicity of gemcitabine and pemetrexed and pharmacogenetic evaluation of response to gemcitabine in bladder cancer patients Br J Cancer 95 289 297 10.1038/sj.bjc.6603242 1:CAS:528:DC%2BD28Xnsl2iu7s%3D 16868547 (Pubitemid 44187589)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.3
, pp. 289-297
-
-
Mey, V.1
Giovannetti, E.2
De Braud, F.3
Nannizzi, S.4
Curigliano, G.5
Verweij, F.6
De Cobelli, O.7
Pece, S.8
Del Tacca, M.9
Danesi, R.10
-
18
-
-
41549095093
-
Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients
-
10.1158/1078-0432.CCR-07-1364 1:CAS:528:DC%2BD1cXjtleju78%3D 18347182
-
C Tibaldi E Giovannetti E Vasile V Mey AC Laan S Nannizzi R Di Marsico A Antonuzzo C Orlandini S Ricciardi M Del Tacca GJ Peters A Falcone R Danesi 2008 Correlation of CDA, ERCC1, and XPD polymorphisms with response and survival in gemcitabine/cisplatin-treated advanced non-small cell lung cancer patients Clin Cancer Res 14 1797 1803 10.1158/1078-0432.CCR-07-1364 1:CAS:528: DC%2BD1cXjtleju78%3D 18347182
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1797-1803
-
-
Tibaldi, C.1
Giovannetti, E.2
Vasile, E.3
Mey, V.4
Laan, A.C.5
Nannizzi, S.6
Di Marsico, R.7
Antonuzzo, A.8
Orlandini, C.9
Ricciardi, S.10
Del Tacca, M.11
Peters, G.J.12
Falcone, A.13
Danesi, R.14
-
19
-
-
33846958737
-
Involvement of ribonucleotide reductase M1 subunit overexpression in gemcitabine resistance of human pancreatic cancer
-
DOI 10.1002/ijc.22390
-
S Nakahira S Nakamori M Tsujie Y Takahashi J Okami S Yoshioka M Yamasaki S Marubashi I Takemasa A Miyamoto Y Takeda H Nagano K Dono K Umeshita M Sakon M Monden 2007 Involvement of ribonucleotide reductase M1 subunit overexpression in gemcitabine resistance of human pancreatic cancer Int J Cancer 120 1355 1363 10.1002/ijc.22390 1:CAS:528:DC%2BD2sXhvVOisr0%3D 17131328 (Pubitemid 46256791)
-
(2007)
International Journal of Cancer
, vol.120
, Issue.6
, pp. 1355-1363
-
-
Nakahira, S.1
Nakamori, S.2
Tsujie, M.3
Takahashi, Y.4
Okami, J.5
Yoshioka, S.6
Yamasaki, M.7
Marubashi, S.8
Takemasa, I.9
Miyamoto, A.10
Takeda, Y.11
Nagano, H.12
Dono, K.13
Umeshita, K.14
Sakon, M.15
Monden, M.16
-
20
-
-
43649096317
-
Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine
-
DOI 10.1038/sj.bjc.6604344, PII 6604344
-
J Souglakos I Boukovinas M Taron P Mendez D Mavroudis M Tripaki D Hatzidaki A Koutsopoulos E Stathopoulos V Georgoulias R Rosell 2008 Ribonucleotide reductase subunits M1 and M2 mRNA expression levels and clinical outcome of lung adenocarcinoma patients treated with docetaxel/gemcitabine Br J Cancer 98 1710 1715 10.1038/sj.bjc.6604344 1:CAS:528:DC%2BD1cXlvVWhsb8%3D 18414411 (Pubitemid 351684679)
-
(2008)
British Journal of Cancer
, vol.98
, Issue.10
, pp. 1710-1715
-
-
Souglakos, J.1
Boukovinas, I.2
Taron, M.3
Mendez, P.4
Mavroudis, D.5
Tripaki, M.6
Hatzidaki, D.7
Koutsopoulos, A.8
Stathopoulos, E.9
Georgoulias, V.10
Rosell, R.11
-
21
-
-
34047177069
-
Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells
-
DOI 10.1016/j.phrs.2007.01.003, PII S1043661807000175
-
E Giovannetti V Mey L Loni S Nannizzi G Barsanti G Savarino R Del Tacca R Danesi 2007 Cytotoxic activity of gemcitabine and correlation with expression profile of drug-related genes in human lymphoid cells Pharmacological Res 55 343 349 10.1016/j.phrs.2007.01.003 1:CAS:528:DC%2BD2sXjvFGntrs%3D (Pubitemid 46518163)
-
(2007)
Pharmacological Research
, vol.55
, Issue.4
, pp. 343-349
-
-
Giovannetti, E.1
Mey, V.2
Loni, L.3
Nannizzi, S.4
Barsanti, G.5
Savarino, G.6
Ricciardi, S.7
Del Tacca, M.8
Danesi, R.9
-
22
-
-
0019505985
-
Evaluation of 5'-nucleotidase as an enzyme marker in ovarian carcinoma
-
DOI 10.1002/1097-0142(19810601)47:11<2648::AID-CNCR2820471121>3.0. CO;2-R
-
SK Chatterjee M Bhattacharya JJ Barlow 1981 Evaluation of 5′-nucleotidase as an enzyme marker in ovarian carcinoma Cancer 47 2648 2653 10.1002/1097-0142(19810601)47:11<2648::AID-CNCR2820471121>3.0.CO;2-R 1:CAS:528:DyaL3MXktlymtrw%3D 6266638 (Pubitemid 11113730)
-
(1981)
Cancer
, vol.47
, Issue.11
, pp. 2648-2653
-
-
Chatterjee, S.K.1
Bhattacharya, M.2
Barlow, J.J.3
-
23
-
-
8644236778
-
Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors
-
DOI 10.1002/ijc.20524
-
X Farré E Guillen-Gomez L Sanchez D Hardisson Y Plaza J Lloberas FJ Casado J Palacios M Pastor-Anglada 2004 Expression of the nucleoside-derived drug transporters hCNT1, hENT1 and hENT2 in gynecologic tumors Int J Cancer 112 959 966 10.1002/ijc.20524 15386342 (Pubitemid 39507001)
-
(2004)
International Journal of Cancer
, vol.112
, Issue.6
, pp. 959-966
-
-
Farre, X.1
Guillen-Gomez, E.2
Sanchez, L.3
Hardisson, D.4
Plaza, Y.5
Lloberas, J.6
Casado, F.J.7
Palacios, J.8
Pastor-Anglada, M.9
-
24
-
-
34250656618
-
A case of drug resistant clear cell ovarian cancer showing responsiveness to gemcitabine at first administration and at re-challenge
-
DOI 10.1007/s00280-007-0479-7
-
G Ferrandina F Legge V Mey S Nannizzi S Ricciardi M Petrillo G Corrado G Scambia 2007 A case of drug resistant clear cell ovarian cancer showing responsiveness to gemcitabine at first administration and at re-challenge Cancer Chemother Pharmacol 60 459 461 10.1007/s00280-007-0479-7 17429624 (Pubitemid 46944591)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, Issue.3
, pp. 459-461
-
-
Ferrandina, G.1
Legge, F.2
Mey, V.3
Nannizzi, S.4
Ricciardi, S.5
Petrillo, M.6
Corrado, G.7
Scambia, G.8
-
25
-
-
0023442604
-
Fitting curves to data using nonlinear regression: A practical and nonmathematical review
-
1:STN:280:DyaL1c%2Fls1SgtQ%3D%3D 3315805
-
HJ Motulsky LA Ransnas 1987 Fitting curves to data using nonlinear regression: a practical and nonmathematical review FASEB J 1 365 374 1:STN:280:DyaL1c%2Fls1SgtQ%3D%3D 3315805
-
(1987)
FASEB J
, vol.1
, pp. 365-374
-
-
Motulsky, H.J.1
Ransnas, L.A.2
-
26
-
-
33845382806
-
Non parametric estimation from incomplete observations
-
10.2307/2281868
-
E Kaplan P Meyer 1958 Non parametric estimation from incomplete observations J Am Statist Assoc 53 457 481 10.2307/2281868
-
(1958)
J Am Statist Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.1
Meyer, P.2
-
27
-
-
0013886333
-
Evaluation of survival data and two new rank order statistics arising in its consideration
-
1:STN:280:DyaF287ht1Wgug%3D%3D 5910392
-
N Mantel 1966 Evaluation of survival data and two new rank order statistics arising in its consideration Cancer Chemother Rep 50 163 170 1:STN:280:DyaF287ht1Wgug%3D%3D 5910392
-
(1966)
Cancer Chemother Rep
, vol.50
, pp. 163-170
-
-
Mantel, N.1
-
28
-
-
0000336139
-
Regression models and life tables
-
DR Cox 1972 Regression models and life tables J R Stat Soc 34 197 220
-
(1972)
J R Stat Soc
, vol.34
, pp. 197-220
-
-
Cox, D.R.1
-
29
-
-
21344452604
-
Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells
-
DOI 10.1016/j.bcp.2005.05.014, PII S0006295205003199
-
M Sarkar T Han V Damaraju P Carpenter CE Cass RP Agarwal 2005 Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells Biochem Pharmacol 70 426 432 10.1016/j.bcp.2005.05.014 1:CAS:528:DC%2BD2MXlvVWms7s%3D 15950950 (Pubitemid 40905114)
-
(2005)
Biochemical Pharmacology
, vol.70
, Issue.3
, pp. 426-432
-
-
Sarkar, M.1
Han, T.2
Damaraju, V.3
Carpenter, P.4
Cass, C.E.5
Agarwal, R.P.6
-
30
-
-
0032188825
-
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines
-
1:CAS:528:DyaK1cXmsVyqsbo%3D 9766663
-
JR Mackey RS Mani M Selner D Mowles JD Young JA Belt CR Crawford CE Cass 1998 Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines Cancer Res 58 4349 4357 1:CAS:528:DyaK1cXmsVyqsbo%3D 9766663
-
(1998)
Cancer Res
, vol.58
, pp. 4349-4357
-
-
MacKey, J.R.1
Mani, R.S.2
Selner, M.3
Mowles, D.4
Young, J.D.5
Belt, J.A.6
Crawford, C.R.7
Cass, C.E.8
-
31
-
-
5044225419
-
Determinants of sensitivity and resistance to gemcitabine: The roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer
-
DOI 10.1111/j.1349-7006.2004.tb03257.x
-
H Achiwa T Oguri S Sato H Maeda T Niimi R Ueda 2004 Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer Cancer Sci 95 753 757 10.1111/j.1349-7006.2004.tb03257.x 1:CAS:528: DC%2BD2cXpvFOgu7w%3D 15471562 (Pubitemid 39335096)
-
(2004)
Cancer Science
, vol.95
, Issue.9
, pp. 753-757
-
-
Achiwa, H.1
Oguri, T.2
Sato, S.3
Maeda, H.4
Niimi, T.5
Ueda, R.6
-
32
-
-
0034994444
-
Nucleoside analogues: Mechanisms of drug resistance and reversal strategies
-
DOI 10.1038/sj.leu.2402114
-
CM Galmarini JR Mackey C Dumontet 2001 Nucleoside analogues: mechanisms of drug resistance and reversal strategies Leukemia 15 875 890 10.1038/sj.leu.2402114 1:CAS:528:DC%2BD3MXkvVOit78%3D 11417472 (Pubitemid 32529886)
-
(2001)
Leukemia
, vol.15
, Issue.6
, pp. 875-890
-
-
Galmarini, C.M.1
Mackey, J.R.2
Dumontet, C.3
-
33
-
-
34247493628
-
Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation In vitro and In vivo
-
DOI 10.1158/1078-0432.CCR-06-2218
-
JD Heidel JY Ching Liu Y Yen B Zhou BSE Heale JJ Rossi DW Bartlett ME Davis 2007 Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo Clin Cancer Res 13 2207 2215 10.1158/1078-0432.CCR-06-2218 1:CAS:528:DC%2BD2sXjs12rtLg%3D 17404105 (Pubitemid 46649891)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.7
, pp. 2207-2215
-
-
Heidel, J.D.1
Liu, J.Y.-C.2
Yen, Y.3
Zhou, B.4
Heale, B.S.E.5
Rossi, J.J.6
Bartlett, D.W.7
Davis, M.E.8
-
34
-
-
34248170858
-
Ribonucleotide reductase: A critical enzyme for cancer chemotherapy and antiviral agents
-
10.2174/157489207779561408 1:CAS:528:DC%2BD2sXhsVWiu74%3D
-
NM Cerqueira PA Fernandes MJ Ramos 2007 Ribonucleotide reductase: a critical enzyme for cancer chemotherapy and antiviral agents Recent Patents Anticancer Drug Discov 2 11 29 10.2174/157489207779561408 1:CAS:528: DC%2BD2sXhsVWiu74%3D
-
(2007)
Recent Patents Anticancer Drug Discov
, vol.2
, pp. 11-29
-
-
Cerqueira, N.M.1
Fernandes, P.A.2
Ramos, M.J.3
-
35
-
-
0034015112
-
Inhibition of human cancer cell growth by inducible expression of human ribonucleotide reductase antisense DNA
-
1:CAS:528:DC%2BD3cXivVKltL4%3D 10805162
-
S Chen B Zhou F He Y Yen 2000 Inhibition of human cancer cell growth by inducible expression of human ribonucleotide reductase antisense DNA Antisense Nucleic Acid Drug Dev 10 111 116 1:CAS:528:DC%2BD3cXivVKltL4%3D 10805162
-
(2000)
Antisense Nucleic Acid Drug Dev
, vol.10
, pp. 111-116
-
-
Chen, S.1
Zhou, B.2
He, F.3
Yen, Y.4
-
36
-
-
0038615898
-
GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors
-
1:CAS:528:DC%2BD3sXkt1ais78%3D 12782585
-
Y Lee A Vassilakos N Feng V Lam H Xie M Wang H Jin K Xiong C Liu J Wright A Young 2003 GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors Cancer Res 63 2802 2811 1:CAS:528:DC%2BD3sXkt1ais78%3D 12782585
-
(2003)
Cancer Res
, vol.63
, pp. 2802-2811
-
-
Lee, Y.1
Vassilakos, A.2
Feng, N.3
Lam, V.4
Xie, H.5
Wang, M.6
Jin, H.7
Xiong, K.8
Liu, C.9
Wright, J.10
Young, A.11
-
37
-
-
3042595897
-
Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors
-
DOI 10.1074/jbc.M402056200
-
ZP Lin MF Belcourt JG Cory AC Sartorelli 2004 Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors J Biol Chem 279 27030 27038 10.1074/jbc.M402056200 1:CAS:528:DC%2BD2cXkvFGns7w%3D 15096505 (Pubitemid 38812539)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.26
, pp. 27030-27038
-
-
Lin, Z.P.1
Belcourt, M.F.2
Cory, J.G.3
Sartorelli, A.C.4
-
38
-
-
1542742114
-
RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine
-
DOI 10.1038/sj.onc.1207272
-
MS Duxbury H Ito MJ Zinner SW Ashley EE Whang 2004 RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine Oncogene. 23 1539 1548 10.1038/sj.onc.1207272 1:CAS:528:DC%2BD2cXhsFOhtrg%3D 14661056 (Pubitemid 38406516)
-
(2004)
Oncogene
, vol.23
, Issue.8
, pp. 1539-1548
-
-
Duxbury, M.S.1
Ito, H.2
Zinner, M.J.3
Ashley, S.W.4
Whang, E.E.5
|