Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: Implications for the reaction mechanism

Biochemistry

Volumn 49, Issue 5, 2010, Pages 934-944

  Grocholski, Thadee ^a   Koskiniemi, Hanna ^b   Lindqvist, Ylva ^b   Mäntsälä, Pekka ^a   Niemi, Jarmo ^a   Schneider, Gunter ^b  

^a UNIVERSITY OF TURKU   (Finland)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ASPARAGINE RESIDUE; CATALYTIC TRIAD; COFACTORS; DIMER INTERFACE; ENZYMATIC ACTIVITIES; ENZYMATIC REACTION; IN-VITRO; MONOOXYGENASES; ONE-ELECTRON TRANSFER; OXYGEN ATOM; POLYKETIDES; REACTION MECHANISM; RESIDUAL ACTIVITY; SITE DIRECTED MUTAGENESIS; SPACE GROUPS; TRYPTOPHAN RESIDUES; WATER MOLECULE;

ACIDS; AMINO ACIDS; BIOCHEMISTRY; CRYSTAL STRUCTURE; ENZYMES; FREE RADICAL REACTIONS;

MOLECULAR OXYGEN;

ASPARAGINE; SNOAB ENZYME; TRYPTOPHAN; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STREPTOMYCES; STREPTOMYCES NOGALATER;

AMINO ACID SEQUENCE; CATALYSIS; COENZYMES; CRYSTALLOGRAPHY, X-RAY; ENZYME STABILITY; KINETICS; MACROLIDES; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NOGALAMYCIN; STREPTOMYCES; SUBSTRATE SPECIFICITY;

STREPTOMYCES NOGALATER;

EID: 75749112037     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901985b     Document Type: Article

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