Immunologic indicators of clinical progression during canine Leishmania infantum infection

Clinical and Vaccine Immunology

Volumn 17, Issue 2, 2010, Pages 267-273

  Boggiatto, Paola M ^a   Ramer Tait, Amanda E ^a   Metz, Kyle ^a,b   Kramer, Erin E ^a,c   Gibson Corley, Katherine ^a   Mullin, Kathleen ^a   Hostetter, Jesse M ^a   Gallup, Jack M ^a   Jones, Douglas E ^a   Petersen, Christine A ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c Charles City Animal Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G2 ANTIBODY; IMMUNOGLOBULIN M; INTERLEUKIN 10; KINETOPLAST DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DOG; FEMALE; HUMORAL IMMUNITY; IMMUNE DYSREGULATION; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; IMMUNOLOGICAL PARAMETERS; IMMUNOMODULATION; IMMUNOPATHOLOGY; LEISHMANIA INFANTUM; LEISHMANIASIS; LYMPHOCYTE PROLIFERATION; NONHUMAN; PARASITE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROGNOSIS; UNITED STATES;

EID: 75749107859     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00456-09     Document Type: Article

References (34)

1. Barbieri, C. L. 2006. Immunology of canine leishmaniasis. Parasite Immunol. 28:329-337.
2. Blackburn, S. D., and E. J. Wherry. 2007. IL-10, T cell exhaustion and viral persistence. Trends Microbiol. 15:143-146.
3. Carvalho, E. M., A. Barral, D. Pedral-Sampaio, M. Barral-Netto, R. Badaro, H. Rocha, and W. D. Johnson, Jr. 1992. Immunologic markers of clinical evolution in children recently infected with Leishmania donovani chagasi. J. Infect. Dis. 165:535-540.
4. Chappuis, F., S. Sundar, A. Hailu, H. Ghalib, S. Rijal, R. W. Peeling, J. Alvar, and M. Boelaert. 2007. Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat. Rev. Microbiol. 5:873-882.
5. Duprey, Z. H., F. J. Steurer, J. A. Rooney, L. V. Kirchhoff, J. E. Jackson, E. D. Rowton, and P. M. Schantz. 2006. Canine visceral leishmaniasis, United States and Canada, 2000-2003. Emerg. Infect. Dis. 12:440-446.
6. Gama, M. E., J. M. Costa, J. C. Pereira, C. M. Gomes, and C. E. Corbett. 2004. Serum cytokine profile in the subclinical form of visceral leishmaniasis. Braz. J. Med. Biol. Res. 37:129-136.
7. Garg, R., S. K. Gupta, P. Tripathi, S. Naik, S. Sundar, and A. Dube. 2005. Immunostimulatory cellular responses of cured Leishmania-infected patients and hamsters against the integral membrane proteins and non-membranous soluble proteins of a recent clinical isolate of Leishmania donovani. Clin. Exp. Immunol. 140:149-156.
8. Gaskin, A. A., P. Schantz, J. Jackson, A. Birkenheuer, L. Tomlinson, M. Gramiccia, M. Levy, F. Steurer, E. Kollmar, B. C. Hegarty, A. Ahn, and E. B. Breitschwerdt. 2002. Visceral leishmaniasis in a New York foxhound kennel. J. Vet. Intern. Med. 16:34-44.
9. Gavgani, A. S., M. H. Hodjati, H. Mohite, and C. R. Davies. 2002. Effect of insecticide-impregnated dog collars on incidence of zoonotic visceral leishmaniasis in Iranian children: a matched-cluster randomised trial. Lancet 360:374-379.
10. Ghalib, H. W., M. R. Piuvezam, Y. A. Skeiky, M. Siddig, F. A. Hashim, A. M. el-Hassan, D. M. Russo, and S. G. Reed. 1993. Interleukin 10 production correlates with pathology in human Leishmania donovani infections. J. Clin. Invest. 92:324-329.
11. Ghalib, H. W., J. A. Whittle, M. Kubin, F. A. Hashim, A. M. el-Hassan, K. H. Grabstein, G. Trinchieri, and S. G. Reed. 1995. IL-12 enhances Th1-type responses in human Leishmania donovani infections. J. Immunol. 154:4623-4629.
12. Gibson-Corley, K. N., J. M. Hostetter, S. J. Hostetter, K. Mullin, A. E. Ramer-Tait, P. M. Boggiatto, and C. A. Petersen. 2008. Disseminated Leishmania infantum infection in two sibling foxhounds due to possible vertical transmission. Can. Vet. J. 49:1005-1008.
13. Jones, D. E., M. R. Ackermann, U. Wille, C. A. Hunter, and P. Scott. 2002. Early enhanced Th1 response after Leishmania amazonensis infection of C57BL/6 interleukin-10-deficient mice does not lead to resolution of infection. Infect. Immun. 70:2151-2158.
14. Jones, D. E., L. U. Buxbaum, and P. Scott. 2000. IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonensis infection. J. Immunol. 165:364-372.
15. Lage, R. S., G. C. Oliveira, S. U. Busek, L. L. Guerra, R. C. Giunchetti, R. Correa-Oliveira, and A. B. Reis. 2007. Analysis of the cytokine profile in spleen cells from dogs naturally infected by Leishmania chagasi. Vet. Immunol. Immunopathol. 115:135-145.
16. Manna, L., S. Reale, F. Vitale, and A. E. Gravino. 2009. Evidence for a relationship between Leishmania load and clinical manifestations. Res. Vet. Sci. 87:76-78.
17. Miles, S. A., S. M. Conrad, R. G. Alves, S. M. Jeronimo, and D. M. Mosser. 2005. A role for IgG immune complexes during infection with the intracellular pathogen Leishmania. J. Exp. Med. 201:747-754.
18. Miro, G., L. Cardoso, M. G. Pennisi, G. Oliva, and G. Baneth. 2008. Canine leishmaniosis. New concepts and insights on an expanding zoonosis: part two. Trends Parasitol. 24:371-377.
19. Mueller, S. N., and R. Ahmed. 2009. High antigen levels are the cause of T cell exhaustion during chronic viral infection. Proc. Natl. Acad. Sci. U. S. A. 106:8623-8628.
20. Murphy, M. L., U. Wille, E. N. Villegas, C. A. Hunter, and J. P. Farrell. 2001. IL-10 mediates susceptibility to Leishmania donovani infection. Eur. J. Immunol. 31:2848-2856.
21. + (Foxp3) regulatory T cells in human visceral leishmaniasis. J. Exp. Med. 204:805-817.
22. Nylen, S., and D. Sacks. 2007. Interleukin-10 and the pathogenesis of human visceral leishmaniasis. Trends Immunol. 28:378-384.
23. Panaro, M. A., O. Brandonisio, A. Cianciulli, P. Cavallo, V. Lacasella, P. Paradies, G. Testini, D. De Caprariis, V. Mitolo, and D. Otranto. 2009. Cytokine expression in dogs with natural Leishmania infantum infection. Parasitology 136:823-831.
24. Petersen, C. A., and S. C. Barr. 2009. Leishmaniasis in North America: emerging or newly recognized? Vet. Clin. North Am. Small Anim. Pract. 39:1065-1074.
25. Quinnell, R. J., O. Courtenay, L. M. Garcez, P. M. Kaye, M. A. Shaw, C. Dye, and M. J. Day. 2003. IgG subclass responses in a longitudinal study of canine visceral leishmaniasis. Vet. Immunol. Immunopathol. 91:161-168.
26. Reis, A. B., A. Teixeira-Carvalho, A. M. Vale, M. J. Marques, R. C. Giunchetti, W. Mayrink, L. L. Guerra, R. A. Andrade, R. Correa-Oliveira, and O. A. Martins-Filho. 2006. Isotype patterns of immunoglobulins: hallmarks for clinical status and tissue parasite density in Brazilian dogs naturally infected by Leishmania (Leishmania) chagasi. Vet. Immunol. Immunopathol. 112:102-116.
27. Roberts, L. J., E. Handman, and S. J. Foote. 2000. Science, medicine, and the future: leishmaniasis. BMJ 321:801-804.
28. Rodriguez-Cortes, A., H. Fernandez-Bellon, A. Ramis, L. Ferrer, J. Alberola, and L. Solano-Gallego. 2007. Leishmania-specific isotype levels and their relationship with specific cell-mediated immunity parameters in canine leishmaniasis. Vet. Immunol. Immunopathol. 116:190-198.
29. Rosypal, A. C., and D. S. Lindsay. 2005. Non-sand fly transmission of a North American isolate of Leishmania infantum in experimentally infected BALB/c mice. J. Parasitol. 91:1113-1115.
30. Rosypal, A. C., G. C. Troy, A. M. Zajac, R. B. Duncan, Jr., K. Waki, K. P. Chang, and D. S. Lindsay. 2003. Emergence of zoonotic canine leishmaniasis in the United States: isolation and immunohistochemical detection of Leishmania infantum from foxhounds from Virginia. J. Eukaryot. Microbiol. 50(Suppl.):691-693.
31. Sacks, D. L., S. L. Lal, S. N. Shrivastava, J. Blackwell, and F. A. Neva. 1987. An analysis of T cell responsiveness in Indian kala-azar. J. Immunol. 138:908-913.
32. Schantz, P. M., F. J. Steurer, Z. H. Duprey, K. P. Kurpel, S. C. Barr, J. E. Jackson, E. B. Breitschwerdt, M. G. Levy, and J. C. Fox. 2005. Autochthonous visceral leishmaniasis in dogs in North America. J. Am. Vet. Med. Assoc. 226:1316-1322.
33. Solano-Gallego, L., A. Koutinas, G. Miro, L. Cardoso, M. G. Pennisi, L. Ferrer, P. Bourdeau, G. Oliva, and G. Baneth. 2009. Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis. Vet. Parasitol. 165:1-18.
34. White, A. C., Jr., M. Castes, L. Garcia, D. Trujillo, and L. Zambrano. 1992. Leishmania chagasi antigens recognized in cured visceral leishmaniasis and asymptomatic infection. Am. J. Trop. Med. Hyg. 46:123-131.