Facile identification and quantitation of protein phosphorylation via β-elimination and Michael addition with natural abundance and stable isotope labeled thiocholine

Analytical Chemistry

Volumn 82, Issue 1, 2010, Pages 163-171

  Chen, Meng ^a,b   Su, Xiong ^a   Yang, Jingyue ^a   Jenkins, Christopher M ^a   Cedars, Ari M ^a   Gross, Richard W ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLISION INDUCED DISSOCIATION; DETECTION LIMITS; EFFICIENT STRATEGY; FRAGMENT IONS; HIGH PRECISION; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; MICHAEL ADDITIONS; NATURAL ABUNDANCE; NEGATIVE CHARGE; NEUTRAL LOSS; PEPTIDE BONDS; PEPTIDIC FRAGMENTS; PHOSPHOPEPTIDES; PHOSPHOPROTEOMICS; POSITIVE CHARGES; PROTEIN PHOSPHORYLATION; QUATERNARY AMINES; RATIOMETRIC; SPECIFIC DETECTION; STABLE ISOTOPES; TANDEM MASS SPECTROMETRY; THIOCHOLINE; THIOLATES; TRIMETHYLAMINE;

ADDITION REACTIONS; CHEMICAL BONDS; CHEMICAL DETECTION; CHEMICAL PROPERTIES; CHROMATOGRAPHIC ANALYSIS; IONIZATION OF LIQUIDS; IONS; ISOTOPES; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC COMPOUNDS; PEPTIDES;

PHOSPHORYLATION;

PHOSPHOLIPASE A2 GROUP IV; THIOCHOLINE;

ANIMAL; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION REGULATION; INSECT; METABOLISM; PHOSPHORYLATION;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; GROUP IV PHOSPHOLIPASES A2; INSECTS; MOLECULAR STRUCTURE; PHOSPHORYLATION; THIOCHOLINE;

EID: 75749094816     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9015193     Document Type: Article

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