Truncated fluorocyclopentenyl pyrimidines as S-adenosylhomocysteine hydrolase inhibitors

Nucleosides, Nucleotides and Nucleic Acids

Volumn 28, Issue 5-7, 2009, Pages 601-613

  Park, Yeon Hee ^a   Choi, Won Jun ^a   Tipnis, Amol S ^a   Lee, Kang Man ^a   Jeong, Lak Shin ^a  

^a Ewha Womans University   (South Korea)

Author keywords

Electrophilic fluorination; S adenosylhomocysteine hydrolase; Truncated nucleosides

Indexed keywords

1 (2 FLUORO 4,5 DIHYDROXY CYCLOPENT 2 ENYL) 1H PYRIMIDINE 2,4 DIONE; 4 AMINO 1 (2 FLUORO 4,5 DIHYDROXY CYCLOPENT 2 ENYL) 1H PYRIMIDIN 2 ONE; ADENOSYLHOMOCYSTEINASE; ADENOSYLHOMOCYSTEINASE INHIBITOR; ANTINEOPLASTIC AGENT; ELECTROPHILE; PYRIMIDINE DERIVATIVE; RIBOSE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME INHIBITION; FIBROSARCOMA; FLUORINATION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; SARCOMA CELL; STOMACH CANCER;

ADENOSYLHOMOCYSTEINASE; CELL LINE, TUMOR; CELL SURVIVAL; FLUORINE COMPOUNDS; HUMANS; PYRIMIDINES;

EID: 75749089989     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770903054316     Document Type: Article

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