Vitamin C supplements and the risk of age-related cataract: A population-based prospective cohort study in women

American Journal of Clinical Nutrition

Volumn 91, Issue 2, 2010, Pages 487-493

  Rautiainen, Susanne ^a   Lindblad, Birgitta Ejdervik ^a,b   Morgenstern, Ralf ^a   Wolk, Alicja ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SUNDSVALL HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID;

ADULT; AGE RELATED CATARACT; AGED; ARTICLE; CATARACT; CATARACT EXTRACTION; CONTROLLED STUDY; FEMALE; FOLLOW UP; HORMONE SUBSTITUTION; HUMAN; MAJOR CLINICAL STUDY; POPULATION RESEARCH; RISK ASSESSMENT; VITAMIN SUPPLEMENTATION;

AGE FACTORS; AGED; AGED, 80 AND OVER; ASCORBIC ACID; CATARACT; COHORT STUDIES; DIETARY SUPPLEMENTS; FEMALE; HUMANS; INCIDENCE; MIDDLE AGED; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; SWEDEN;

ANIMALIA;

EID: 75649152844     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.3945/ajcn.2009.28528     Document Type: Article

References (45)

1. Chiu CJ, Taylor A. Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res 2007;84:229-45.
2. Lou MF. Redox regulation in the lens. Prog Retin Eye Res 2003;22: 657-82.
3. Linetsky M, Shipova E, Cheng R, Ortwerth BJ. Glycation by ascorbic acid oxidation products leads to the aggregation of lens proteins. Biochim Biophys Acta 2008;1782:22-34.
4. Cheng R, Lin B, Lee KW, Ortwerth BJ. Similarity of the yellow chromophores isolated from human cataracts with those from ascorbic acid-modified calf lens proteins: evidence for ascorbic acid glycation during cataract formation. Biochim Biophys Acta 2001;1537:14-26.
5. Cheng R, Feng Q, Ortwerth BJ. LC-MS display of the total modified amino acids in cataract lens proteins and in lens proteins glycated by ascorbic acid in vitro. Biochim Biophys Acta 2006;1762:533-43.
6. Linetsky M, James HL, Ortwerth BJ. Spontaneous generation of superoxide anion by human lens proteins and by calf lens proteins ascorbylated in vitro. Exp Eye Res 1999;69:239-48.
7. Fan X, Reneker LW, Obrenovich ME, et al. Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model. Proc Natl Acad Sci USA 2006;103:16912-7.
8. Gritz DC, Srinivasan M, Smith SD, et al. The Antioxidants in Prevention of Cataracts Study: effects of antioxidant supplements on cataract progression in South India. Br J Ophthalmol 2006;90:847-51.
9. AREDS Study. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 2001;119:1439-52.
10. Sperduto RD, Hu TS, Milton RC, et al. The Linxian cataract studies. Two nutrition intervention trials. Arch Ophthalmol 1993;111:1246-53.
11. Chylack LT Jr, Brown NP, Bron A, et al. The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Ophthalmic Epidemiol 2002;9:49-80.
12. Klein BE, Knudtson MD, Lee KE, et al. Supplements and age-related eye conditions: The Beaver Dam Eye Study. Ophthalmology 2008;115: 1203-8.
13. Seddon JM, Christen WG, Manson JE, et al. The use of vitamin supplements and the risk of cataract among US male physicians. Am J Public Health 1994;84:788-92.
14. Leske MC, Chylack LT Jr, He Q, et al. Antioxidant vitamins and nuclear opacities: the longitudinal study of cataract. Ophthalmology 1998;105: 831-6.
15. Chasan-Taber L, Willett WC, Seddon JM, et al. A prospective study of vitamin supplement intake and cataract extraction among U.S. women. Epidemiology 1999;10:679-84.
16. Taylor A, Jacques PF, Chylack LT Jr, et al. Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Am J Clin Nutr 2002;75:540-9.
17. Mares-Perlman JA, Lyle BJ, Klein R, et al. Vitamin supplement use and incident cataracts in a population-based study. Arch Ophthalmol 2000; 118:1556-63.
18. Jacques PF, Chylack LT Jr, Hankinson SE, et al. Long-term nutrient intake and early age-related nuclear lens opacities. Arch Ophthalmol 2001;119:1009-19.
19. Pou KM, Massaro JM, Hoffmann U, et al. Visceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of in-flammation and oxidative stress: the Framingham Heart Study. Circulation 2007;116:1234-41.
20. Szabo G, Mandrekar P, Oak S, Mayerle J. Effect of ethanol on in-flammatory responses. Implications for pancreatitis. Pancreatology 2007;7:115-23.
21. Salpeter SR, Walsh JM, Ormiston TM, Greyber E, Buckley NS, Salpeter EE. Meta-analysis: effect of hormone-replacement therapy on components of the metabolic syndrome in postmenopausal women. Diabetes Obes Metab 2006;8:538-54.
22. Urban Jr RC, Cotlier E. Corticosteroid-induced cataracts. Surv Ophthalmol 1986;31:102-10.
23. Lindblad BE, Hakansson N, Svensson H, Philipson B, Wolk A. Intensity of smoking and smoking cessation in relation to risk of cataract extraction: a prospective study of women. Am J Epidemiol 2005;162:73-9.
24. Messerer M, Wolk A. Sensitivity and specificity of self-reported use of dietary supplements. Eur J Clin Nutr 2004;58:1669-71.
25. Holmquist C, Larsson S, Wolk A, de Faire U. Multivitamin supplements are inversely associated with risk of myocardial infarction in men and women-Stockholm Heart Epidemiology Program (SHEEP). J Nutr 2003;133:2650-4.
26. Messerer M, Johansson SE, Wolk A. The validity of questionnaire-based micronutrient intake estimates is increased by including dietary supplement use in Swedish men. J Nutr 2004;134:1800-5.
27. National Cataract Register 08/11/08, Nationella Kataraktregistret Eye-Net Sweden, Blekingesjukhuset, 371 85 Karlskrona, Sweden. Available from: http://www.cataractreg.com/Cataract-Sve/forstasida.htm (cited 8 November 2008).
28. Mattsson B, Wallgren A. Completeness of Swedish Cancer Register. Non-notified cancer cases recorded on death certificates in 1978. Acta Radiol Oncol 1984;23:305-13.
29. Cox D. Regression models and life-tables. J Roy Stat Soc B 1972;34: 187-220.
30. Orsini N, Bellocco R, Bottai M, Wolk A, Greenland S. A tool for deterministic and probabilistic sensitivity analysis of epidemiologic studies. Stata J 2008;8:29-48.
31. Fox MP, Lash TL, Greenland S. A method to automate probabilistic sensitivity analyses of misclassified binary variables. Int J Epidemiol 2005;34:1370-6.
32. Rothman KJ, Greenland S, Lash TL. Modern epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2008.
33. Assmann SF, Hosmer DW, Lemeshow S, Mundt KA. Confidence intervals for measures of interaction. Epidemiology 1996;7:286-90.
34. Andersson T, Alfredsson L, Kallberg H, Zdravkovic S, Ahlbom A. Calculating measures of biological interaction. Eur J Epidemiol 2005; 20:575-9.
35. Reddy VN, Giblin FJ, Lin LR, Chakrapani B. The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium. Invest Ophthalmol Vis Sci 1998;39:344-50.
36. Tung WH, Chylack LT Jr, Andley UP. Lens hexokinase deactivation by near-UV irradiation. Curr Eye Res 1988;7:257-63.
37. Reddy GB, Bhat KS. Protection against UVB inactivation (in vitro) of rat lens enzymes by natural antioxidants. Mol Cell Biochem 1999;194: 41-5.
38. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007;39:44-84.
39. Truscott RJ. Age-related nuclear cataract-oxidation is the key. Exp Eye Res 2005;80:709-25.
40. Lindblad BE, Hakansson N, Philipson B, Wolk A. Alcohol consumption and risk of cataract extraction: a prospective cohort study of women. Ophthalmology 2007;114:680-5.
41. Lindblad BE, Hakansson N, Philipson B, Wolk A. Hormone replacement therapy in relation to risk of cataract extraction-a prospective study of women. Ophthalmology (in press).
42. Schaumberg DA, Ridker PM, Glynn RJ, Christen WG, Dana MR, Hennekens CH. High levels of plasma C-reactive protein and future risk of age-related cataract. Ann Epidemiol 1999;9:166-71.
43. Cumming RG, Mitchell P. Inhaled corticosteroids and cataract: prevalence, prevention and management. Drug Saf 1999;20:77-84.
44. Levine M, Wang Y, Padayatty SJ, Morrow J. A new recommended dietary allowance of vitamin C for healthy young women. Proc Natl Acad Sci USA 2001;98:9842-6.
45. Taylor A, Jacques PF, Nowell T, et al. Vitamin C in human and guinea pig aqueous, lens and plasma in relation to intake. Curr Eye Res 1997;16:857-64.