Hemocompatibility of a miniaturized extracorporeal membrane oxygenation and a pumpless interventional lung assist in experimental lung injury

Artificial Organs

Volumn 34, Issue 1, 2010, Pages 13-21

  Kopp, Ruedger ^a   Bensberg, Ralf ^a   Henzler, Dietrich ^a,c   Niewels, Anja ^a   Randerath, Simone ^a   Rossaint, Rolf ^a   Kuhlen, Ralf ^b  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b Helios Hospital Berlin Buch   (Germany)

^c DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Adult respiratory distress syndrome; Blood coagulation; Extracorporeal membrane oxygenation; Hemocompatibility testing; Heparin

Indexed keywords

BIOLOGICAL ORGANS; COAGULATION; ENZYMES; OXYGEN; OXYGENATION; OXYGENATORS; PLATELETS; RESPIRATORY SYSTEM;

ADULT RESPIRATORY DISTRESS SYNDROME; BLOOD COAGULATION; BLOOD PUMP; EXTRACORPOREAL MEMBRANE OXYGENATION; HAEMOCOMPATIBILITY; HEMOCOMPATIBILITY TESTING; INTERVENTIONAL; LUNG INJURY; PUMPLESS; RESPIRATORY DISTRESS SYNDROME;

RESPIRATORY THERAPY;

INTERLEUKIN 8; THROMBIN ANTITHROMBIN COMPLEX; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD PUMP; CONTROLLED STUDY; DEVICE; ELECTRONICS; EXTRACORPOREAL CIRCULATION; EXTRACORPOREAL OXYGENATION; FEMALE; HEMOLYSIS; HISTOCOMPATIBILITY; IMMUNE SYSTEM; INTERMETHOD COMPARISON; LUNG INJURY; NONHUMAN; OXYGENATOR; PERFUSION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SWINE; THROMBOCYTE COUNT; THROMBOELASTOGRAPHY;

SUIDAE;

EID: 75649147724     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2009.00791.x     Document Type: Article

References (22)

1. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000 342 : 1301 1308.
2. Kopp R, Dembinski R, Kuhlen R. Role of extracorporeal lung assist in the treatment of acute respiratory failure. Minerva Anestesiol 2006 72 : 587 595.
3. Hemmila MR, Rowe SA, Boules TN, et al. Extracorporeal life support for severe acute respiratory distress syndrome in adults. Ann Surg 2004 240 : 595 605.
4. Lewandowski K. Extracorporeal membrane oxygenation for severe acute respiratory failure. Crit Care 2000 4 : 156 168.
5. Wendel HP, Ziemer G. Coating-techniques to improve the hemocompatibility of artificial devices used for extracorporeal circulation. Eur J Cardiothorac Surg 1999 16 : 342 350.
6. Zimmermann AK, Weber N, Aebert H, Ziemer G, Wendel HP. Effect of biopassive and bioactive surface-coatings on the hemocompatibility of membrane oxygenators. J Biomed Mater Res B Appl Biomater 2007 80 : 433 439.
7. Conrad SA, Zwischenberger JB, Grier LR, Alpard SK, Bidani A. Total extracorporeal arteriovenous carbon dioxide removal in acute respiratory failure: a phase I clinical study. Intensive Care Med 2001 27 : 1340 1351.
8. Bein T, Weber F, Philipp A, et al. A new pumpless extracorporeal interventional lung assist in critical hypoxemia/hypercapnia. Crit Care Med 2006 34 : 1372 1377. (Pubitemid 43754558)
9. Dembinski R, Kopp R, Henzler D, et al. Extracorporeal gas exchange with the Deltastream rotary blood pump in experimental lung injury. Artif Organs 2003 27 : 530 536.
10. Dembinski R, Max M, Lopez F, Kuhlen R, Kurth R, Rossaint R. Effect of inhaled prostacyclin in combination with almitrine on ventilation-perfusion distributions in experimental lung injury. Anesthesiology 2001 94 : 461 467.
11. Richterich R. Klinische Chemie: Theorie und Praxis, 2nd Edition. Basel : S. Karger AG, 1968.
12. Ravanat C, Freund M, Dol F, et al. Cross-reactivity of human molecular markers for detection of prethrombotic states in various animal species. Blood Coagul Fibrinolysis 1995 6 : 446 455.
13. Mueller XM, Tevaearai HT, Jegger D, Tucker O, von Segesser LK. Are standard human coagulation tests suitable in pigs and calves during extracorporeal circulation? Artif Organs 2001 25 : 579 584.
14. Murphy JA, Savage CM, Alpard SK, Deyo DJ, Jayroe JB, Zwischenberger JB. Low-dose versus high-dose heparinization during arteriovenous carbon dioxide removal. Perfusion 2001 16 : 460 468.
15. Ovrum E, Holen EA, Tangen G, et al. Completely heparinized cardiopulmonary bypass and reduced systemic heparin: clinical and hemostatic effects. Ann Thorac Surg 1995 60 : 365 371.
16. Keldenich S, Kopp R, Kirschfink M, et al. Application of a new dynamic flow model for investigating the biocompatibility of modified surfaces. ASAIO J 2000 46 : 134 141.
17. Ovrum E, Tangen G, Oystese R, Ringdal MA, Istad R. Comparison of two heparin-coated extracorporeal circuits with reduced systemic anticoagulation in routine coronary artery bypass operations. J Thorac Cardiovasc Surg 2001 121 : 324 330.
18. Philipp A, Muller T, Bein T, et al. Inhibition of thrombocyte aggregation during extracorporeal lung assist: a case report. Perfusion 2007 22 : 293 298.
19. Gobel C, Arvand A, Rau G, et al. A new rotary blood pump for versatile extracorporeal circulation: the DeltaStream. Perfusion 2002 17 : 373 382.
20. Peek GJ, Firmin RK. The inflammatory and coagulative response to prolonged extracorporeal membrane oxygenation. ASAIO J 1999 45 : 250 263.
21. Mei YQ, Ji Q, Liu H, et al. Study on the relationship of APACHE III and levels of cytokines in patients with systemic inflammatory response syndrome after coronary artery bypass grafting. Biol Pharm Bull 2007 30 : 410 414.
22. Meyns B, Vercaemst L, Vandezande E, Bollen H, Vlasselaers D. Plasma leakage of oxygenators in ECMO depends on the type of oxygenator and on patient variables. Int J Artif Organs 2005 28 : 30 4.