Pumilio 2 controls translation by competing with eIF4E for 7-methyl guanosine cap recognition

RNA

Volumn 16, Issue 1, 2010, Pages 221-227

  Cao, Quiping ^a   Padmanabhan, Kiran ^a,b   Richter, Joel D ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cap; Pumilio; Translation

Indexed keywords

7 METHYLGUANOSINE; INITIATION FACTOR 4E; MESSENGER RNA; PROTEIN; PUMILIO 2 PROTEIN; UNCLASSIFIED DRUG; 7-METHYLGUANOSINE; CAPPED RNA; DRUG DERIVATIVE; GUANOSINE; PUMILIO 2 PROTEIN, XENOPUS; RNA BINDING PROTEIN; XENOPUS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA CAPPING; RNA STABILITY; RNA STRUCTURE; TRANSLATION REGULATION; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; BIOLOGICAL MODEL; CELL CULTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY; XENOPUS LAEVIS;

VERTEBRATA;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CELLS, CULTURED; EUKARYOTIC INITIATION FACTOR-4E; GUANOSINE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; RNA CAPS; RNA STABILITY; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; XENOPUS LAEVIS; XENOPUS PROTEINS;

EID: 75649147451     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.1884610     Document Type: Article

References (44)

1. Barnard DC, Ryan K, Manley JL, Richter JD. 2004. Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation. Cell 119: 641-645. (Pubitemid 39535752)
2. Baron-Benhamou J, Gehring NH, Kulozik AE, Hentze MW. 2004. Using the λN peptide to tether proteins to RNAs. Methods Mol Biol 257: 135-154.
3. Cao Q, Richter JD. 2002. Dissolution of the maskin-eIF4E complex by cytoplasmic polyadenylation and poly(A)-binding protein controls cyclin B1 mRNA translation and oocyte maturation. EMBO J 21: 3852-3862. (Pubitemid 34787057)
4. Cao Q, Kim JH, Richter JD. 2006. CDK1 and calcineurin regulate Maskin association with eIF4E and translational control of cell cycle progression. Nat Struct Mol Biol 13: 1128-1133. (Pubitemid 44885925)
5. Cho PF, Poulin F, Cho-Park YA, Cho-Park IB, Chicoine JD, Lasko P, Sonenberg N. 2005. A new paradigm for translational control: Inhibition via 5′-3′ mRNA tethering by Bicoid and the eIF4E cognate 4EH. Cell 121: 411-423. (Pubitemid 40692301)
6. Collier B, Gorgoni B, Loveridge C, Cooke HJ, Gray NK. 2005. The DAZL family proteins are PABP-binding proteins that regulate translation in germ cells. EMBO J 24: 2656-2666. (Pubitemid 41076321)
7. Deng Y, Singer RH, Gu W. 2008. Translation of Ash1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes & Dev 22: 1037-1050. (Pubitemid 351544242)
8. Derry MC, Yanagiya A, Martineau Y, Sonenberg N. 2006. Regulation of poly(A)-binding protein through PABP-interacting proteins. Cold Spring Harb Symp Quant Biol 71: 537-543.
9. Eulalio A, Huntzinger E, Izaurralde E. 2008. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol 15: 346-353. (Pubitemid 351483394)
10. Evdokimova V, Ruzanov P, Imataka H, Raught B, Svitkin Y, Ovchinnikov LP, Sonenberg N. 2001. The major mRNA-associated protein YB-1 is a potent 5′ cap-dependent mRNA stabilizer. EMBO J 20: 5491-5502. (Pubitemid 32959469)
11. Fechter P, Brownlee GG. 2005. Recognition of mRNA cap structures by viral and cellular proteins. J Gen Virol 86: 1239-1249. (Pubitemid 40613240)
12. 2/M progression in Xenopus oocytes. Genes & Dev 13: 2177-2189.
13. Goldstrohm AC, Hook BA, Seay DJ, Wickens M. 2006. PUF proteins bind POP2p to regulate mRNAs. Nat Struct Mol Biol 13: 533-539. (Pubitemid 43848908)
14. Gu W, Deng Y, Zenklusen D, Singer RH. 2004. A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization. Genes & Dev 18: 1452-1465. (Pubitemid 38780631)
15. Hook BA, Goldstrohm AC, Seay DJ, Wickens M. 2007. Two yeast PUF proteins negatively regulate a single mRNA. J Biol Chem 282: 15430-15438. (Pubitemid 47093267)
16. Hu G, Gershon PD, Hodel AE, Quiocho FA. 1999. mRNA cap recognition: Dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc Natl Acad Sci 96: 7149-7154. (Pubitemid 29299630)
17. Hüttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH. 2005. Spatial regulation of β-actin translation by Src-dependent phosphorylation of ZBP1. Nature 438: 512-515. (Pubitemid 41742024)
18. Kaye JA, Rose NC, Goldsworthy B, Goga A, L'Etoile ND. 2009. A 3′UTR pumilio-binding element directs translational activation in olfactory sensory neuron. Neuron 61: 57-70.
19. Keady BT, Kuo P, Martínez SE, Yuan L, Hake LE. 2007. MAPK interacts with XGef and is required for CPEB activation during meiosis in Xenopus oocytes. J Cell Sci 120: 1093-1103. (Pubitemid 46638522)
20. Kim JH, Richter JD. 2006. Opposing polymerase-deadenylase activities regulate cytoplasmic polyadenylation. Mol Cell 24: 173-183.
21. Kim JH, Richter JD. 2007. RINGO/cdk1 and CPEB mediate poly(A) tail stabilization and translational regulation by ePAB. Genes & Dev 21: 2571-2579.
22. Kimble J, Crittenden SL. 2007. Controls of germline stem cells, entry into mitosis, and sperm/oocyte decision in Caenorhabtidis elegans. Annu Rev Cell Dev Biol 23: 405-433.
23. Kiriakidou M, Tan GS, Lamprinaki S, De Planell-Saguer M, Nelson PT, Mourelatos Z. 2007. An mRNA m7G cap binding-like motif within human Ago2 represses translation. Cell 129: 1141-1151. (Pubitemid 46891041)
24. Lu G, Dolgner SJ, Hall TMT. 2009. Understanding and engineering RNA sequence specificity of PUF proteins. Curr Opin Struct Biol 19: 110-115.
25. Mendez R, Hake LE, Andresson T, Littlepage LE, Ruderman JV, Richter JD. 2000. Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA. Nature 404: 302-307. (Pubitemid 30163550)
26. Mendez R, Barnard D, Richter JD. 2002. Differential mRNA translation and meiotic progression require cdc2-mediated CPEB destruction. EMBO J 21: 1833-1844. (Pubitemid 34614639)
27. Mochida S, Hunt T. 2007. Calcineurin is required to release Xenopus egg extracts from meiotic M phase. Nature 449: 336-340. (Pubitemid 47443474)
28. Napoli I, Mercaldo V, Boyl PP, Eleuteri B, Zalfa F, De Rubeis S, Di Marino D, Mohr E, Massimi M, Falconi M, et al. 2008. The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell 134: 1042-1054.
29. Nakamura A, Sato K, Hanyu-Nakamura K. 2004. Drosophila Cup is an eIF4E binding protein that associates with bruno and regulates oskar mRNA translation in oogenesis. Dev Cell 6: 69-78. (Pubitemid 38089206)
30. Niedzwiecka A, Marcotrigiano J, Stepinski J, Jankowska-Anyszka M, Wyslouch-Cieszynska A, Dadlez M, Gingras AC, Mak P, Darzynkiewicz E, Sonenberg N, et al. 2002. Biophysical studies of eIF4E cap-binding protein: Recognition of mRNA 5′ cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. J Mol Biol 319: 615-635. (Pubitemid 34729439)
31. Nottrott S, Simard MJ, Richter JD. 2006. Human let-7a miRNA blocks protein production on actively translating polyribosomes. Nat Struct Mol Biol 13: 1108-1114. (Pubitemid 44885922)
32. Ostareck DH, Ostareck-Lederer A, Shatsky IN, Hentze MW. 2001. Lipoxygenase mRNA silencing in erythroid differentiation: The 3′UTR regulatory complex controls 60S ribosomal subunit joining. Cell 104: 281-290. (Pubitemid 32174843)
33. Padmanabhan K, Richter JD. 2006. Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation. Genes & Dev 20: 199-209. (Pubitemid 43112938)
34. Rauh NR, Schmidt A, Borman J, Nigg EA, Mayer TU. 2005. Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation. Nature 437: 1048-1052. (Pubitemid 41486988)
35. Rhoads RE. 2009. eIF4E: New family members, new binding partners, new roles. J Biol Chem 284: 16711-16715.
36. Richter JD. 2006. CPEB: A life in translation. Trends Biochem Sci 32: 279-285.
37. Richter JD, Sonenberg N. 2005. Regulation of cap-dependent translation by eIF4E inhibitory proteins. Nature 433: 477-480. (Pubitemid 40204297)
38. Scheper GC, van Kollenburg B, Hu J, Luo Y, Goss DJ, Proud CG. 2002. Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA. J Biol Chem 277: 3303-3309. (Pubitemid 34953196)
39. 7GDP. Proc Natl Acad Sci 76: 4345-4349.
40. Stebbins-Boaz B, Cao Q, de Moorm CH, Mendez R, Richter JD. 1999. Maskin is a CPEB-associated factor that transiently interacts with elF-4E. Mol Cell 4: 1017-1027. (Pubitemid 30054907)
41. Vuillard L, Marret N, Rabilloud T. 1995. Enhancing protein solubilization with nondetergent sulfobetaines. Electrophoresis 16: 295-297.
42. Wang X, Zamore PD, Hall TM. 2001. Crystal structure of a Pumilio homology domain. Mol Cell 7: 855-865. (Pubitemid 32436445)
43. Wharton RP, Sonoda J, Lee T, Patterson M. 1998. The Pumilio RNA-binding domain is also a translational regulator. Mol Cell 1: 863-872. (Pubitemid 128379070)
44. Wilson FK, Fortes P, Singh U, Ohno M, Mattaj IW, Cerione RA. 1999. The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction. J Biol Chem 274: 4166-4173. (Pubitemid 129503056)