Lesion of the subthalamic nucleus reverses motor deficits but not death of nigrostriatal dopaminergic neurons in a rat 6-hydroxydopamine-lesion model of Parkinson's disease

Brazilian Journal of Medical and Biological Research

Volumn 43, Issue 1, 2010, Pages 85-95

  Rizelio, V ^a   Szawka, R E ^b   Xavier, L L ^c   Achaval, M ^d   Rigon, P ^d   Saur, L ^d   Matheussi, F ^a   Delattre, A M ^a   Anselmo Franci, J A ^b   Meneses, M ^a   Ferraz, A C ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

6 Hydroxydopamine; Parkinson's disease; Substantia nigra pars compacta; Subthalamic nucleus; Tyrosine hydroxylase immunohistochemistry

Indexed keywords

APOMORPHINE; DOPAMINE; N METHYL DEXTRO ASPARTIC ACID; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; CEREBROSPINAL FLUID; CONTROL GROUP; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FOREBRAIN; INJECTION; MALE; METABOLITE; MOTOR DYSFUNCTION; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OPEN FIELD TEST; PARKINSON DISEASE; RAT; ROTATION; STEREOTAXIC SURGERY; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 75649109261     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/s0100-879x2009007500020     Document Type: Article

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