A 12-month outcome study of insight and symptom change in first-episode psychosis

Early Intervention in Psychiatry

Volumn 4, Issue 1, 2010, Pages 79-88

  Buchy, Lisa ^a   Bodnar, Michael ^a,b   Malla, Ashok ^b,c   Joober, Ridha ^b,c   Lepage, Martin ^a,b,c  

^a DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Anxiety; Awareness of illness; Depression; First episode schizophrenia; Positive and negative symptoms

Indexed keywords

ADULT; ANXIETY; ARTICLE; BIPOLAR DISORDER; CLINICAL INDICATOR; DELUSIONAL DISORDER; DEPRESSION; FEMALE; HAMILTON ANXIETY SCALE; HUMAN; ILLNESS TRAJECTORY; INTROSPECTION; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; OUTCOME ASSESSMENT; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; PSYCHOSIS; SCALE TO ASSESS UNAWARENESS OF MENTAL DISORDER; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SCHIZOPHRENIFORM DISORDER;

ADOLESCENT; ADULT; ANTIPSYCHOTIC AGENTS; ANXIETY; AWARENESS; DEPRESSION; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MODELS, STATISTICAL; PSYCHOTIC DISORDERS; SCHIZOPHRENIC PSYCHOLOGY; TREATMENT OUTCOME;

EID: 75649102511     PISSN: 17517885     EISSN: 17517893     Source Type: Journal    
DOI: 10.1111/j.1751-7893.2010.00166.x     Document Type: Article

References (34)

1. Carpenter WT, Strauss JS, Bartko JJ. Flexible system for the diagnosis of schizophrenia: report from the WHO International Pilot Study of Schizophrenia. Science 1973, 182(118):1275-8. Dec 21
2. Amador XF, Flaum M, Andreasen NC. Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 1994, 51:826-36.
3. Fennig S, Everett E, Bromet EJ. Insight in first-admission psychotic patients. Schizophr Res 1996, 22:257-63.
4. McEvoy JP, Johnson J, Perkins D. Insight in first-episode psychosis. Psychol Med 2006, 36:1385-93.
5. Saeedi H, Addington J, Addington D. The association of insight with psychotic symptoms, depression, and cognition in early psychosis: a 3-year follow-up. Schizophr Res 2007, 89:123-8.
6. Crumlish N, Whitty P, Kamali M. Early insight predicts depression and attempted suicide after 4 years in first-episode schizophrenia and schizophreniform disorder. Acta Psychiatr Scand 2005, 112:449-55.
7. Mintz AR, Addington J, Addington D. Insight in early psychosis: a 1-year follow-up. Schizophr Res 2004, 67:213-17.
8. Agid O, Kapur S, Arenovich T, Zipursky RB. Delayed-onset hypothesis of antipsychotic action: a hypothesis tested and rejected. Arch Gen Psychiatry 2003, 60:1228-35.
9. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV Patient Edition (SCID-I/P V and SCID-I/NP Version 2.0) 1998, New York, Biometric Research Department
10. Malla A, Norman R, Schmitz N. Predictors of rate and time to remission in first-episode psychosis: a two-year outcome study. Psychol Med 2006, 36:649-58.
11. Malla AK, Norman RM, Manchanda R. One year outcome in first episode psychosis: influence of DUP and other predictors. Schizophr Res 2002, 54:231-42.
12. Arduini L, Kalyvoka A, Stratta P, Rinaldi O, Daneluzzo E, Rossi A. Insight and neuropsychological function in patients with schizophrenia and bipolar disorder with psychotic features. Can J Psychiatry 2003, 48:338-41.
13. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry 2003, 64:663-7.
14. Cassidy CM, Rabinovitch M, Joober R, Malla A. Is Any One Method of Measuring Medication Adherence in First-episode Psychosis Better than Others? 2007, Montreux, Winter Workshop on Schizophrenia and Bipolar Disorders, February 2008
15. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987, 13:261-76.
16. Addington D, Addington J, Schissel B. A depression rating scale for schizophrenics. Schizophr Res 1990, 3:247-51.
17. Riskind J, Beck A, Brown G, Steer R. Taking the measure of anxiety and depression: validity of the reconstructed Hamilton Scales. J Nerv Ment Dis 1987, 175:474-9.
18. Jones BF, Nagin DS, Roeder K. A SAS procedure based on mixture models for estimating developmental trajectories. Sociol Methods Res 2001, 29:374-93.
19. Enders CK. A primer on maximum likelihood algorithms available for use with missing data. Struct Equ Modeling 2001, 8:128-41.
20. Startup M, Jackson MC, Startup S. Insight and recovery from acute psychotic episodes: the effects of cognitive behavior therapy and premature termination of treatment. J Nerv Ment Dis 2006, 194:740-5.
21. Park HJ, Levitt J, Shenton ME. An MRI study of spatial probability brain map differences between first-episode schizophrenia and normal controls. Neuroimage 2004, 22(3):1231-46. Jul
22. Turkington D, Kingdon D, Turner T. Effectiveness of a brief cognitive-behavioural therapy intervention in the treatment of schizophrenia. Br J Psychiatry 2002, 180:523-7.
23. Hasson-Ohayon I, Kravetz S, Roe D, David AS, Weiser M. Insight into psychosis and quality of life. Compr Psychiatry 2006, 47:265-9.
24. Lysaker PH, Bell MD, Bryson GJ, Kaplan E. Insight and interpersonal function in schizophrenia. J Nerv Ment Dis 1998, 186:432-6.
25. Karow A, Pajonk FG, Reimer J. The dilemma of insight into illness in schizophrenia: self- and expert-rated insight and quality of life. Eur Arch Psychiatry Clin Neurosci 2008, 258:152-9.
26. Schwartz RC, Smith SD. Suicidality and psychosis: the predictive potential of symptomatology and insight into illness. J Psychiatr Res 2004, 38:185-91.
27. Schwartz RC. Insight and suicidality in schizophrenia: a replication study. J Nerv Ment Dis 2000, 188:235-7.
28. Schwartz RC, Petersen S. The relationship between insight and suicidality among patients with schizophrenia. J Nerv Ment Dis 1999, 187:376-8.
29. Hirayasu Y, Tanaka S, Shenton ME. Prefrontal gray matter volume reduction in first episode schizophrenia. Cereb Cortex 2001, 11:374-81.
30. Malla AK, Norman RM, Takhar J. Can patients at risk for persistent negative symptoms be identified during their first episode of psychosis? J Nerv Ment Dis 2004, 192:455-63.
31. Jaspers K. General Psychopathology 1963, Chicago, IL, University of Chicago Press
32. Mintz AR, Dobson KS, Romney DM. Insight in schizophrenia: a meta-analysis. Schizophr Res 2003, 61:75-88.
33. Pini S, Cassano GB, Dell'Osso L, Amador XF. Insight into illness in schizophrenia, schizoaffective disorder, and mood disorders with psychotic features. Am J Psychiatry 2001, 158:122-5.
34. Amador XF, Strauss DH, Yale SA, Flaum MM, Endicott J, Gorman JM. Assessment of insight in psychosis. Am J Psychiatry 1993, 150:873-9.