The dilemma of insight into illness in schizophrenia: Self- and expert-rated insight and quality of life

European Archives of Psychiatry and Clinical Neuroscience

Volumn 258, Issue 3, 2008, Pages 152-159

  Karow, A ^a   Pajonk, F G ^a   Reimer, J ^a   Hirdes, F ^a   Osterwald, C ^a   Naber, D ^a   Moritz, S ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Insight; PANSS; Quality of life; Schizophrenia

Indexed keywords

BENZODIAZEPINE DERIVATIVE; NEUROLEPTIC AGENT;

ADULT; ARTICLE; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DEPRESSION; DRUG DOSE COMPARISON; DRUG MEGADOSE; FEMALE; HOSPITAL PATIENT; HUMAN; INTROSPECTION; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL EXPERT; POSITIVE AND NEGATIVE SYNDROME SCALE; PRIORITY JOURNAL; QUALITY OF LIFE; RATING SCALE; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SELF CONCEPT; SOCIAL INTERACTION; SOCIAL PSYCHOLOGY;

ADULT; AWARENESS; COST OF ILLNESS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; QUALITY OF LIFE; SCHIZOPHRENIC PSYCHOLOGY; SELF ASSESSMENT (PSYCHOLOGY); SELF CONCEPT; STATISTICS, NONPARAMETRIC;

EID: 43149089387     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-007-0768-5     Document Type: Article

References (47)

1. Amador XF, Flaum M, Andreasen NC, Strauss DH, Yale SA, Clark SC, Gorman JM (1994) Awareness of illness in schizophrenia and schizoaffective and mood disorders. Arch Gen Psychiatry 51:826-836
2. Amador XF, Strauss DH, Yale SA, Flaum MM, Endicott J, Gorman JM (1993) Assessment of insight in psychosis. Am J Psychiatry 150:873-879
3. an der Heiden W, Konnecke R, Maurer K, Ropeter D, Hafner H (2005) Depression in the long-term course of schizophrenia. Eur Arch Psychiatry Clin Neurosci 255:174-184
4. Bell M, Fiszdon J, Richardson R, Lysaker P, Bryson G (2007) Are self-reports valid for schizophrenia patients with poor insight? Relationship of unawareness of illness to psychological self-report instruments. Psychiatry Res 151:37-46
5. Bell MD, Lysaker PH, Beam-Goulet JL, Milstein RM, Lindenmayer JP (1994) Five-component model of schizophrenia: assessing the factorial invariance of the positive and negative syndrome scale. Psychiatry Res 52:295-303
6. Birchwood M, Smith J, Drury V, Healy J, Macmillan F, Slade M (1994) A self-report insight scale for psychosis: reliability, validity and sensitivity to change. Acta Psychiatr Scand 89:62-67
7. Bora E, Sehitoglu G, Aslier M, Atabay I, Veznedaroglu B (2007) Theory of mind and unawareness of illness in schizophrenia: is poor insight a mentalizing deficit? Eur Arch Psychiatry Clin Neurosci 257:104-111
8. Browne S, Garavan J, Gervin M, Roe M, Larkin C, O'Callaghan E (1998) Quality of life in schizophrenia: insight and subjective response to neuroleptics. J Nerv Ment Dis 186:74-78
9. Bullinger M (2003) Measuring health related quality of life. An international perspective. Adv Exp Med Biol 528:113-122
10. Carroll A, Fattah S, Clyde Z, Coffey I, Owens DG, Johnstone EC (1999) Correlates of insight and insight change in schizophrenia. Schizophr Res 35:247-253
11. Cooke MA, Peters ER, Kuipers E, Kumari V (2005) Disease, deficit or denial? Models of poor insight in psychosis. Acta Psychiatr Scand 112:4-17
12. Dickerson FB, Boronow JJ, Ringel N, Parente F (1997) Lack of insight among outpatients with schizophrenia. Psychiatric Serv 48:195-199
13. Dilling H, Dittmann V (1990) Psychiatric diagnosis following the 10th revision of the international classification of diseases (ICD-10). Nervenarzt 61:259-270
14. Drake RJ, Lewis SW (2003) Insight and neurocognition in schizophrenia. Schizophr Res 62:165-173
15. Drake RJ, Pickles A, Bentall RP, Kinderman P, Haddock G, Tarrier N, Lewis SW (2004) The evolution of insight, paranoia and depression during early schizophrenia. Psychol Med 34:285-292
16. Gilleen J, David AS (2005) The cognitive neuropsychiatry of delusions: from psychopathology to neuropsychology and back again. Psychol Med 35:5-12
17. Goldberg RW, Green-Paden LD, Lehman AF, Gold JM (2001) Correlates of insight in serious mental illness. J Nerv Ment Dis 189:137-145
18. Hasson-Ohayon I, Kravetz S, Roe D, David AS, Weiser M (2006) Insight into psychosis and quality of life. Compr Psychiatry 47:265-269
19. Hofer A, Rettenbacher MA, Widschwendter CG, Kemmler G, Hummer M, Fleischhacker WW (2005) Correlates of subjective and functional outcomes in outpatient clinic attendees with schizophrenia and schizoaffective disorder. Eur Arch Psychiatry Clin Neurosci
20. Iqbal Z, Birchwood M, Chadwick P, Trower P (2000) Cognitive approach to depression and suicidal thinking in psychosis. 2. Testing the validity of a social ranking model. Br J Psychiatry 177:522-528
21. Jovanovski D, Zakzanis KK, Atia M, Campbell Z, Young DA (2007) A comparison between a researcher-rated and a self-report method of insight assessment in chronic schizophrenia revisited: a replication study using the SUMD and SAIQ. J Nerv Ment Dis 195:165-169
22. Karow A, Czekalla J, Dittmann RW, Schacht A, Wagner T, Lambert M, Schimmelmann BG, Naber D (2007) Association of subjective well-being, symptoms, and side effects with compliance after 12 months of treatment in schizophrenia. J Clin Psych 68:75-80
23. Karow A, Moritz S, Lambert M, Schoder S, Krausz M (2005) PANSS syndromes and quality of life in schizophrenia. Psychopathology 38:320-326
24. Karow A, Naber D (2002) Subjective well-being and quality of life under atypical antipsychotic treatment. Psychopharmacology 162:3-10
25. Karow A, Pajonk FG (2006) Insight and quality of life in schizophrenia: recent findings and treatment implications. Curr Opin Psych 19:637-641
26. Kim CH, Jayathilake K, Meltzer HY (2003) Hopelessness, neurocognitive function, and insight in schizophrenia: relationship to suicidal behavior. Schizophr Res 60:71-80
27. Koren D, Seidman LJ, Poyurovsky M, Goldsmith M, Viksman P, Zichel S, Klein E (2004) The neuropsychological basis of insight in first-episode schizophrenia: a pilot metacognitive study. Schizophr Res 70:195-202
28. Lambert M, Naber D, Eich FX, Schacht M, Linden M, Schimmelmann BG (2007) Remission of severely impaired subjective wellbeing in 727 patients with schizophrenia treated with amisulpride. Acta Psychiatr Scand 115:106-113
29. Liraud F, Droulout T, Parrot M, Verdoux H (2004) Agreement between self-rated and clinically assessed symptoms in subjects with psychosis. J Nerv Ment Dis 192:352-356
30. Lysaker PH, Bell MD, Bryson GJ, Kaplan E (1998) Insight and interpersonal function in schizophrenia. J Nerv Ment Dis 186:432-436
31. McEvoy JP, Apperson LJ, Appelbaum PS, Ortlip P, Brecosky J, Hammill K, Geller JL, Roth L (1989) Insight in schizophrenia. Its relationship to acute psychopathology. J Nerv Ment Dis 177:43-47
32. Mintz AR, Addington J, Addington D (2004) Insight in early psychosis: a 1-year follow-up. Schizophr Res 67:213-217
33. Moritz S, Werner R, Collani Gv. The inferiority complex in paranoia re-addressed. A study with the implicit association test. (in press)
34. Pedrelli P, McQuaid JR, Granholm E, Patterson TL, McClure F, Beck AT, Jeste DV (2004) Measuring cognitive insight in middle-aged and older patients with psychotic disorders. Schizophr Res 71:297-305
35. Pukrop R, Moller HJ, Steinmeyer EM (2000) Quality of life in psychiatry: a systematic contribution to construct validation and the development of the integrative assessment tool "modular system for quality of life". Eur Arch Psychiatry Clin Neurosci 250:120-132
36. Pukrop R, Schlaak V, Moller-Leimkuhler AM, Albus M, Czernik A, Klosterkotter J, Moller HJ (2003) Reliability and validity of quality of life assessed by the short-form 36 and the modular system for quality of life in patients with schizophrenia and patients with depression. Psychiatry Res 119:63-79
37. Ritsner M (2003) Predicting changes in domain-specific quality of life of schizophrenia patients. J Nerv Ment Dis 191:287-294
38. Sanz M, Constable G, Lopez-Ibor I, Kemp R, David AS (1998) A comparative study of insight scales and their relationship to psychopathological and clinical variables. Psychol Med 28:437-446
39. Schwartz RC (1998) Insight and illness in chronic schizophrenia. Comp Psychiatry 39:249-254
40. Schwartz RC, Smith SD (2004) Suicidality and psychosis: the predictive potential of symptomatology and insight into illness. J Psychiatr Res 38:185-191
41. Sim K, Mahendran R, Siris SG, Heckers S, Chong SA (2004) Subjective quality of life in first episode schizophrenia spectrum disorders with comorbid depression. Psychiatry Res 129:141-147
42. Smith TE, Hull JW, Huppert JD, Silverstein SM, Anthony DT, McClough JF (2004) Insight and recovery from psychosis in chronic schizophrenia and schizoaffective disorder patients. J Psychiatr Res 38:169-176
43. Subotnik KL, Nuechterlein KH, Irzhevsky V, Kitchen CM, Woo SM, Mintz J (2005) Is unawareness of psychotic disorder a neurocognitive or psychological defensiveness problem? Schiz Res 75:147-157
44. Vaz FJ, Bejar A, Casado M (2002) Insight, psychopathology, and interpersonal relationships in schizophrenia. Schizophr Bull 28:311-317
45. Whitty P, Browne S, Clarke M, McTigue O, Waddington J, Kinsella T, Larkin C, O'Callaghan E (2004) Systematic comparison of subjective and objective measures of quality of life at 4-year follow-up subsequent to a first episode of psychosis. J Nerv Ment Dis 192:805-809
46. Williams CC, Collins A (2002) Factors associated with insight among outpatients with serious mental illness. Psychiatr Serv 53:96-98
47. Young DA, Campbell Z, Zakzanis KK, Weinstein E (2003) A comparison between an interview and a self-report method of insight assessment in chronic schizophrenia. Schiz Res 63:103-109