Pharmacological characterization of (3-thienylidene)-3,4- methylenedioxybenzoylhydrazide: A novel muscarinic agonist with antihypertensive profile

American Journal of Hypertension

Volumn 23, Issue 2, 2010, Pages 135-141

  Zapata Sudo, Gisele ^a   Pereira, Sharlene L ^a   Beiral, Hellen J V ^a   Kummerle, Arthur E ^a   Raimundo, Juliana M ^a   Antunes, Fernanda ^b   Sudo, Roberto T ^a   Barreiro, Eliezer J ^a   Fraga, Carlos A M ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

Author keywords

Blood pressure; Hypertension; Muscarinic receptor; N acylhydrazone; Vasodilation

Indexed keywords

(3 THIENYLIDENE) 3,4 METHYLENEDIOXYBENZOYLHYDRAZIDE; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ATROPINE; CYCLIC GMP; GUANYLATE CYCLASE INHIBITOR; LASSBIO 897; MUSCARINIC AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLEPHRINE; SAFROLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; ISOMETRICS; MALE; NONHUMAN; OCOTEA; PRIORITY JOURNAL; RAT; SASSAFRAS; THORACIC AORTA; VASCULAR RING; VASODILATATION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA, THORACIC; BENZODIOXOLES; BLOOD PRESSURE; CYCLIC GMP; HYPERTENSION; INJECTIONS, INTRAVENOUS; MALE; MUSCARINIC AGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, MUSCARINIC; THIOPHENES; VASODILATION;

EID: 75549086228     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1038/ajh.2009.238     Document Type: Article

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