-
1
-
-
0036561332
-
Novel extranuclear-targeted anthracyclines override the anti-apoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis
-
Barrett CM, Lewis FL, Roaten JB, Sweatman TW, Israel M, Cleveland JL et al. (2002) Novel extranuclear-targeted anthracyclines override the anti-apoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis. Mol Cancer Ther 1:469-481
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 469-481
-
-
Barrett, C.M.1
Lewis, F.L.2
Roaten, J.B.3
Sweatman, T.W.4
Israel, M.5
Cleveland, J.L.6
-
2
-
-
0024468481
-
DNA topoisomerase II-mediated interaction of doxorubicin and daunor-ubicin congeners with DNA
-
Bodley A, Liu LF, Israel M, Seshadri R, Koseki Y, Giuliani FC et al. (1989) DNA topoisomerase II-mediated interaction of doxorubicin and daunor-ubicin congeners with DNA. Cancer Res 49:5969-5978
-
(1989)
Cancer Res
, vol.49
, pp. 5969-5978
-
-
Bodley, A.1
Liu, L.F.2
Israel, M.3
Seshadri, R.4
Koseki, Y.5
Giuliani, F.C.6
-
3
-
-
0014695964
-
Clinical evaluation of adriamycin, a new antitumour antibiotic
-
Bonadonna G, Monfardini S, De LM, Fossati-Bellani F (1969) Clinical evaluation of adriamycin, a new antitumour antibiotic. Br Med J 3:503-506
-
(1969)
Br Med J
, vol.3
, pp. 503-506
-
-
Bonadonna, G.1
Monfardini, S.2
De, L.M.3
Fossati-Bellani, F.4
-
4
-
-
25444435193
-
Getting under the skin: The immunogenetics of psoriasis
-
Bowcock AM, Krueger JG (2005) Getting under the skin: the immunogenetics of psoriasis. Nat Rev Immunol 5:699-711
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 699-711
-
-
Bowcock, A.M.1
Krueger, J.G.2
-
5
-
-
0024360612
-
A fluorescence study examining how 14-valerate side chain substitution modulates anthracy-cline binding to small unilamellar phospholipid vesicles
-
Burke TG, Israel M, Seshadri R, Doroshow JH (1989) A fluorescence study examining how 14-valerate side chain substitution modulates anthracy-cline binding to small unilamellar phospholipid vesicles. Biochim Biophys Acta 982:123-130
-
(1989)
Biochim Biophys Acta
, vol.982
, pp. 123-130
-
-
Burke, T.G.1
Israel, M.2
Seshadri, R.3
Doroshow, J.H.4
-
6
-
-
0025409045
-
Abrogation of the selectivity of adriamycin for negatively-charged phospholipids by 14-valerate side chain substitution
-
Burke TG, Israel M, Seshadri R, Doroshow JH (1990) Abrogation of the selectivity of adriamycin for negatively-charged phospholipids by 14-valerate side chain substitution. Cancer Biochem Biophys 11:177-185
-
(1990)
Cancer Biochem Biophys
, vol.11
, pp. 177-185
-
-
Burke, T.G.1
Israel, M.2
Seshadri, R.3
Doroshow, J.H.4
-
7
-
-
0026578239
-
Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32)
-
Chuang LF, Kung HF, Israel M, Chuang RY (1992) Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32). Biochem Pharmacol 43: 865-872
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 865-872
-
-
Chuang, L.F.1
Kung, H.F.2
Israel, M.3
Chuang, R.Y.4
-
8
-
-
0020692452
-
Effect of N-trifluoroacetyladriamycin-14-valerate on [3H]thymidine uptake and DNA synthesis of human lymphoma cells
-
Chuang RY, Chuang LF, Kawahata RT, Israel M (1983) Effect of N-trifluoroacetyladriamycin-14-valerate on [3H]thymidine uptake and DNA synthesis of human lymphoma cells. J Biol Chem 258:1062-1065
-
(1983)
J Biol Chem
, vol.258
, pp. 1062-1065
-
-
Chuang, R.Y.1
Chuang, L.F.2
Kawahata, R.T.3
Israel, M.4
-
9
-
-
0033233456
-
1alpha,25-Dihydroxycho-lecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice
-
Dam TN, Kang S, Nickoloff BJ, Voorhees JJ (1999) 1alpha,25-Dihydroxycho- lecalciferol and cyclosporine suppress induction and promote resolution of psoriasis in human skin grafts transplanted on to SCID mice. J Invest Dermatol 113:1082-1089
-
(1999)
J Invest Dermatol
, vol.113
, pp. 1082-1089
-
-
Dam, T.N.1
Kang, S.2
Nickoloff, B.J.3
Voorhees, J.J.4
-
10
-
-
0021747592
-
Comparative microscopic study of cardiotoxicity and skin toxicity of anthracycline analogs
-
Dantchev D, Balercia G, Bourut C, Anjo A, Maral R, Mathe G (1984) Comparative microscopic study of cardiotoxicity and skin toxicity of anthracycline analogs. Biomed Pharmacother 38:322-328
-
(1984)
Biomed Pharmacother
, vol.38
, pp. 322-328
-
-
Dantchev, D.1
Balercia, G.2
Bourut, C.3
Anjo, A.4
Maral, R.5
Mathe, G.6
-
11
-
-
0019280927
-
Ultrastructural study of the cardiotoxicity and light-microscopic findings of the skin after treatment of golden hamsters with seven different anthracyclines
-
Dantchev D, Slioussartchouk V, Paintrand M, Bourut C, Hayat M, Mathe G (1980) Ultrastructural study of the cardiotoxicity and light-microscopic findings of the skin after treatment of golden hamsters with seven different anthracyclines. Recent Results Cancer Res 74:223-249
-
(1980)
Recent Results Cancer Res
, vol.74
, pp. 223-249
-
-
Dantchev, D.1
Slioussartchouk, V.2
Paintrand, M.3
Bourut, C.4
Hayat, M.5
Mathe, G.6
-
12
-
-
1942438618
-
Epidermal keratinocytes: Regulation of multiple cell phenotypes by multiple protein kinase C isoforms
-
Denning MF (2004) Epidermal keratinocytes: regulation of multiple cell phenotypes by multiple protein kinase C isoforms. Int J Biochem Cell Biol 36:1141-1146
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1141-1146
-
-
Denning, M.F.1
-
13
-
-
0014473575
-
Adriamycin (NSC-123,127): A new antibiotic with antitumor activity
-
Di Marco A, Gaetani M, Scarpinato B (1969) Adriamycin (NSC-123,127): a new antibiotic with antitumor activity. Cancer Chemother Rep 53:33-37
-
(1969)
Cancer Chemother Rep
, vol.53
, pp. 33-37
-
-
Di Marco, A.1
Gaetani, M.2
Scarpinato, B.3
-
14
-
-
47349099978
-
Genetics of psoriasis and psoriatic arthritis: Update and future direction
-
Duffin KC, Chandran V, Gladman DD, Krueger GG, Elder JT, Rahman P (2008) Genetics of psoriasis and psoriatic arthritis: update and future direction. J Rheumatol 35:1449-1453
-
(2008)
J Rheumatol
, vol.35
, pp. 1449-1453
-
-
Duffin, K.C.1
Chandran, V.2
Gladman, D.D.3
Krueger, G.G.4
Elder, J.T.5
Rahman, P.6
-
15
-
-
63149095611
-
Genetic variations in cytokines and cytokine receptors associated with psoriasis found by genome-wide association
-
Duffin KC, Krueger GG (2009) Genetic variations in cytokines and cytokine receptors associated with psoriasis found by genome-wide association. J Invest Dermatol 129:827-833
-
(2009)
J Invest Dermatol
, vol.129
, pp. 827-833
-
-
Duffin, K.C.1
Krueger, G.G.2
-
16
-
-
0018167235
-
A differential interaction of daunomycin, adriamycin, and N-trifluoroacetyladriamycin 14-valerate with mouse peritoneal macrophages
-
Facchinetti T, Raz A, Goldman R (1978) A differential interaction of daunomycin, adriamycin, and N-trifluoroacetyladriamycin 14-valerate with mouse peritoneal macrophages. Cancer Res 38:3944-3949
-
(1978)
Cancer Res
, vol.38
, pp. 3944-3949
-
-
Facchinetti, T.1
Raz, A.2
Goldman, R.3
-
17
-
-
37349131221
-
Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines
-
Fitch E, Harper E, Skorcheva I, Kurtz SE, Blauvelt A (2007) Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr Rheumatol Rep 9:461-467
-
(2007)
Curr Rheumatol Rep
, vol.9
, pp. 461-467
-
-
Fitch, E.1
Harper, E.2
Skorcheva, I.3
Kurtz, S.E.4
Blauvelt, A.5
-
18
-
-
0030968305
-
Initial report on intravesical administration of N-trifluoroacetyla- driamycin-14-valerate (AD 32) to patients with refractory superficial transitional cell carcinoma of the urinary bladder
-
Greenberg RE, Bahnson RR, Wood D, Childs SJ, Bellingham C, Edson M et al. (1997) Initial report on intravesical administration of N-trifluoroacetyla- driamycin-14-valerate (AD 32) to patients with refractory superficial transitional cell carcinoma of the urinary bladder. Urology 49:471-475
-
(1997)
Urology
, vol.49
, pp. 471-475
-
-
Greenberg, R.E.1
Bahnson, R.R.2
Wood, D.3
Childs, S.J.4
Bellingham, C.5
Edson, M.6
-
19
-
-
0016739792
-
N-trifluoroacetyladriamycin-14-valerate, an analog with greater experimental antitumor activity and less toxicity than adriamycin
-
Israel M, Modest EJ, Frei E III (1975) N-trifluoroacetyladriamycin-14- valerate, an analog with greater experimental antitumor activity and less toxicity than adriamycin. Cancer Res 35:1365-1368
-
(1975)
Cancer Res
, vol.35
, pp. 1365-1368
-
-
Israel, M.1
Modest, E.J.2
Frei, E.I.I.I.3
-
20
-
-
0018773717
-
Effects of N-trifluoroacetyladriamycin-14-valerate and related agents on DNA strand damage and thymidine incorporation in CCRF-CEM cells
-
Kanter PM, Schwartz HS (1979) Effects of N-trifluoroacetyladriamycin-14- valerate and related agents on DNA strand damage and thymidine incorporation in CCRF-CEM cells. Cancer Res 39:448-451
-
(1979)
Cancer Res
, vol.39
, pp. 448-451
-
-
Kanter, P.M.1
Schwartz, H.S.2
-
21
-
-
0002246502
-
Preparation of isolated sheets of human stratum corneum
-
Kligman MA, Christophers E (1963) Preparation of isolated sheets of human stratum corneum. Arch Dermatol 88:702-705
-
(1963)
Arch Dermatol
, vol.88
, pp. 702-705
-
-
Kligman, M.A.1
Christophers, E.2
-
22
-
-
0019410760
-
Comparative effects of adriamycin and N-trifluoroacetyladriamycin-14- valerate on cell kinetics, chromosomal damage, and macromolecular synthesis in vitro
-
Krishan A, Dutt K, Israel M, Ganapathi R (1981) Comparative effects of adriamycin and N-trifluoroacetyladriamycin-14-valerate on cell kinetics, chromosomal damage, and macromolecular synthesis in vitro. Cancer Res 41:2745-2750
-
(1981)
Cancer Res
, vol.41
, pp. 2745-2750
-
-
Krishan, A.1
Dutt, K.2
Israel, M.3
Ganapathi, R.4
-
23
-
-
0017069173
-
Differences in cellular uptake and cytofluorescence of adriamycin and N-trifluoroacetyladriamycin-14-valerate
-
Krishan A, Israel M, Modest EJ, Frei E III (1976) Differences in cellular uptake and cytofluorescence of adriamycin and N-trifluoroacetyladriamycin-14- valerate. Cancer Res 36:2108-2109
-
(1976)
Cancer Res
, vol.36
, pp. 2108-2109
-
-
Krishan, A.1
Israel, M.2
Modest, E.J.3
Frei, E.I.I.I.4
-
24
-
-
58149316658
-
Induction of IL-17+ T cell trafficking and development by IFN-gamma: Mechanism and pathological relevance in psoriasis
-
Kryczek I, Bruce AT, Gudjonsson JE, Johnston A, Aphale A, Vatan L et al. (2008) Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis. J Immunol 181:4733-4741
-
(2008)
J Immunol
, vol.181
, pp. 4733-4741
-
-
Kryczek, I.1
Bruce, A.T.2
Gudjonsson, J.E.3
Johnston, A.4
Aphale, A.5
Vatan, L.6
-
25
-
-
0035190606
-
Anthracycline drug targeting: Cytoplasmic versus nuclear\-a fork in the road
-
Lothstein L, Israel M, Sweatman TW (2001) Anthracycline drug targeting: cytoplasmic versus nuclear\-a fork in the road. Drug Resist Updat 4:169-177
-
(2001)
Drug Resist Updat
, vol.4
, pp. 169-177
-
-
Lothstein, L.1
Israel, M.2
Sweatman, T.W.3
-
26
-
-
0031936753
-
Cytotoxicity and intracellular biotransformation of N-benzyladriamycin- 14-valerate (AD 198) are modulated by changes in 14-O-acyl chain length
-
Lothstein L, Rodrigues PJ, Sweatman TW, Israel M (1998) Cytotoxicity and intracellular biotransformation of N-benzyladriamycin-14-valerate (AD 198) are modulated by changes in 14-O-acyl chain length. Anticancer Drugs 9:58-66
-
(1998)
Anticancer Drugs
, vol.9
, pp. 58-66
-
-
Lothstein, L.1
Rodrigues, P.J.2
Sweatman, T.W.3
Israel, M.4
-
27
-
-
0022476847
-
Low-density lipoprotein as a carrier of antitumoral drugs: In vivo fate of drug-human low-density lipoprotein complexes in mice
-
Masquelier M, Vitols S, Peterson C (1986) Low-density lipoprotein as a carrier of antitumoral drugs: in vivo fate of drug-human low-density lipoprotein complexes in mice. Cancer Res 46:3842-3847
-
(1986)
Cancer Res
, vol.46
, pp. 3842-3847
-
-
Masquelier, M.1
Vitols, S.2
Peterson, C.3
-
28
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L (2004) Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185-229
-
(2004)
Pharmacol Rev
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
29
-
-
0023131330
-
Effects of N-trifluoroace-tyladriamycin-14-valerate (AD-32) on human bladder tumor cell lines
-
Niell HB, Hunter RF, Herrod HG, Israel M (1987) Effects of N-trifluoroace-tyladriamycin-14-valerate (AD-32) on human bladder tumor cell lines. Cancer Chemother Pharmacol 19:47-52
-
(1987)
Cancer Chemother Pharmacol
, vol.19
, pp. 47-52
-
-
Niell, H.B.1
Hunter, R.F.2
Herrod, H.G.3
Israel, M.4
-
30
-
-
34247365979
-
In vitro and in vivo immunosuppressive activity of a novel anthracycline, 13-deoxy, 5-iminodoxorubicin
-
Olson RD, Headley MB, Hodzic A, Walsh GM, Wingett DG (2007) In vitro and in vivo immunosuppressive activity of a novel anthracycline, 13-deoxy, 5-iminodoxorubicin. Int Immunopharmacol 7: 734-743
-
(2007)
Int Immunopharmacol
, vol.7
, pp. 734-743
-
-
Olson, R.D.1
Headley, M.B.2
Hodzic, A.3
Walsh, G.M.4
Wingett, D.G.5
-
32
-
-
0033943168
-
Pilot study of the tolerability and toxicity of intravesical valrubicin immediately after transurethral resection of superficial bladder cancer
-
Patterson AL, Greenberg RE, Weems L, Bahnson R, Wajsman Z, Israel M et al. (2000) Pilot study of the tolerability and toxicity of intravesical valrubicin immediately after transurethral resection of superficial bladder cancer. Urology 56:232-235
-
(2000)
Urology
, vol.56
, pp. 232-235
-
-
Patterson, A.L.1
Greenberg, R.E.2
Weems, L.3
Bahnson, R.4
Wajsman, Z.5
Israel, M.6
-
33
-
-
4344615366
-
Complete resolution of psoriasis in a patient treated with stealth liposomal doxorubicin and carboplatin for ovarian cancer
-
Pisano C, Tambaro R, Di MM, Formato R, Iaffaioli VR, Pignata S (2004) Complete resolution of psoriasis in a patient treated with stealth liposomal doxorubicin and carboplatin for ovarian cancer. Arch Dermatol Res 296:141-142
-
(2004)
Arch Dermatol Res
, vol.296
, pp. 141-142
-
-
Pisano, C.1
Tambaro, R.2
Di Mm Formato, R.3
Iaffaioli, V.R.4
Pignata, S.5
-
34
-
-
33644644954
-
Keratinocyte apoptosis in epidermal development and disease
-
Raj D, Brash DE, Grossman D (2006) Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol 126:243-257
-
(2006)
J Invest Dermatol
, vol.126
, pp. 243-257
-
-
Raj, D.1
Brash, D.E.2
Grossman, D.3
-
35
-
-
0019826748
-
DNA damage by anthracycline drugs in human leukemia cells
-
Schwartz HS, Kanter PM (1981) DNA damage by anthracycline drugs in human leukemia cells. Cancer Lett 13:309-313
-
(1981)
Cancer Lett
, vol.13
, pp. 309-313
-
-
Schwartz, H.S.1
Kanter, P.M.2
-
36
-
-
51349152055
-
The PKC inhibitor AEB071 may be a therapeutic option for psoriasis
-
Skvara H, Dawid M, Kleyn E, Wolff B, Meingassner JG, Knight H et al. (2008) The PKC inhibitor AEB071 may be a therapeutic option for psoriasis. J Clin Invest 118:3151-3159
-
(2008)
J Clin Invest
, vol.118
, pp. 3151-3159
-
-
Skvara, H.1
Dawid, M.2
Kleyn, E.3
Wolff, B.4
Meingassner, J.G.5
Knight, H.6
-
37
-
-
0033973840
-
Efficacy and safety of valrubicin for the treatment of bacillus Calmette-Guerin refractory carcinoma in situ of the bladder
-
Steinberg G, Bahnson R, Brosman S, Middleton R, Wajsman Z, Wehle M (2000) Efficacy and safety of valrubicin for the treatment of Bacillus Calmette-Guerin refractory carcinoma in situ of the bladder. The Valrubicin Study Group. J Urol 163:761-767 (Pubitemid 30091611)
-
(2000)
Journal of Urology
, vol.163
, Issue.3
, pp. 761-767
-
-
Steinberg, G.1
Bahnson, R.2
Brosman, S.3
Middleton, R.4
Wajsman, Z.5
Wehle, M.6
Auerbach, S.7
Blute, M.8
Bohnert, W.9
Brendler, C.10
Bretton, P.11
Brown, T.12
Byrne, J.13
Cohen, J.14
Dalkin, B.15
Deeths, J.16
Dula, E.17
Ellis, W.18
Epstein, H.19
Feldman, R.20
Friedel, W.21
Gleason, D.22
Greenberg, R.23
Hakala, T.24
Heaney, J.25
Ignatoff, J.26
Immergut, M.27
Jackson, C.28
Johnson, C.F.29
Katz, A.30
Klein, E.31
Klimberg, I.32
Lowe, B.33
Moseley, W.34
Murdock, M.35
Narayan, P.36
Sabanegh, E.37
Schmidt, J.38
Schutz, M.39
Soloway, M.40
Tuttle, J.41
Wajsman, Z.42
Weems, L.43
Wehe, M.44
Wilson, T.45
Zinner, N.46
more..
-
38
-
-
58349115638
-
Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model
-
Stenderup K, Rosada C, Worsaae A, Dagnaes-Hansen F, Steiniche T, Hasselager E et al. (2009) Interleukin-20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model. Br J Dermatol 160:284-296
-
(2009)
Br J Dermatol
, vol.160
, pp. 284-296
-
-
Stenderup, K.1
Rosada, C.2
Worsaae, A.3
Dagnaes-Hansen, F.4
Steiniche, T.5
Hasselager, E.6
-
39
-
-
0025911750
-
Pharmacologic rationale for intravesical N-trifluoroacetyladriamycin-14- valerate (AD 32): A preclini-cal study
-
Sweatman TW, Parker RF, Israel M (1991) Pharmacologic rationale for intravesical N-trifluoroacetyladriamycin-14-valerate (AD 32): a preclini-cal study. Cancer Chemother Pharmacol 28:1-6
-
(1991)
Cancer Chemother Pharmacol
, vol.28
, pp. 1-6
-
-
Sweatman, T.W.1
Parker, R.F.2
Israel, M.3
-
40
-
-
0033634750
-
Rationale for intralesional valrubicin in chemoradiation of squamous cell carcinoma of the head and neck
-
Wani MK, Koseki Y, Yarber RH, Sweatman TW, Ahmed A, Samant S et al. (2000) Rationale for intralesional valrubicin in chemoradiation of squamous cell carcinoma of the head and neck. Laryngoscope 110:2026-2032
-
(2000)
Laryngoscope
, vol.110
, pp. 2026-2032
-
-
Wani, M.K.1
Koseki, Y.2
Yarber, R.H.3
Sweatman, T.W.4
Ahmed, A.5
Samant, S.6
-
41
-
-
57649170604
-
Biologic therapies for psoriasis: Practical experience in a UK. tertiary referral centre
-
Warren RB, Brown BC, Lavery D, Ashcroft DM, Griffiths CE (2009) Biologic therapies for psoriasis: practical experience in a UK. tertiary referral centre. Br J Dermatol 160:162-169
-
(2009)
Br J Dermatol
, vol.160
, pp. 162-169
-
-
Warren, R.B.1
Brown, B.C.2
Lavery, D.3
Ashcroft, D.M.4
Griffiths, C.E.5
-
42
-
-
49549084651
-
Activation of keratinocyte protein kinase C zeta in psoriasis plaques
-
Zhao Y, Fishelevich R, Petrali JP, Zheng L, Anatolievna MA, Deng A et al. (2008) Activation of keratinocyte protein kinase C zeta in psoriasis plaques. J Invest Dermatol 128:2190-2197
-
(2008)
J Invest Dermatol
, vol.128
, pp. 2190-2197
-
-
Zhao, Y.1
Fishelevich, R.2
Petrali, J.P.3
Zheng, L.4
Anatolievna, M.A.5
Deng, A.6
|