메뉴 건너뛰기




Volumn 575, Issue , 2009, Pages 207-223

Chemogenomic Analysis of Safety Profiling Data

Author keywords

Chemogenomics; Data Mining; Drug Safety; Safety profiling

Indexed keywords

ARTICLE; BAYES THEOREM; DRUG DEVELOPMENT; DRUG SCREENING; DRUG TOXICITY; GENOMICS; MOLECULAR BIOLOGY; PRINCIPAL COMPONENT ANALYSIS; STATISTICAL ANALYSIS; STATISTICAL MODEL; STATISTICS;

EID: 75549084459     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60761-274-2_9     Document Type: Chapter
Times cited : (8)

References (11)
  • 1
    • 26944446576 scopus 로고    scopus 로고
    • Keynote review: In vitro safety pharmacology profiling: An essential tool for successful drug development
    • Whitebread, S., Hamon, J., Bojanic, D., and Urban, L. (2005) Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development. Drug Discov. Today 10, 1421–1433.
    • (2005) Drug Discov. Today , vol.10 , pp. 1421-1433
    • Whitebread, S.1    Hamon, J.2    Bojanic, D.3    Urban, L.4
  • 2
    • 0000293407 scopus 로고
    • Generation of a unique machine description for chemical structures–a technique developed at Chemical Abstracts Service
    • Morgan, H. L. (1965) Generation of a unique machine description for chemical structures–a technique developed at Chemical Abstracts Service. J. Chem. Doc. 5, 107.
    • (1965) J. Chem. Doc. , vol.5 , pp. 107
    • Morgan, H.L.1
  • 3
    • 33745391215 scopus 로고    scopus 로고
    • Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases
    • Nidhi, Glick, M., Davies, J.W., and Jenkins, J.L. (2006) Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases. J. Chem. Inf. Model. 46, 1124– 1133.
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 1124-1133
    • Nidhi, G.1    Davies, J.W.2    Jenkins, J.L.3
  • 4
    • 4143122120 scopus 로고    scopus 로고
    • Classification of kinase inhib-itors using a Bayesian model
    • Xia, X., Maliski, E. G., Gallant, P., and Rog-ers, D. (2004) Classification of kinase inhib-itors using a Bayesian model. J. Med. Chem. 47, 4463–4470.
    • (2004) J. Med. Chem. , vol.47 , pp. 4463-4470
    • Xia, X.1    Maliski, E.G.2    Gallant, P.3    Rog-Ers, D.4
  • 5
    • 10044254671 scopus 로고    scopus 로고
    • Application of machine learning to improve the results of high-throughput docking against the HIV-1 protease
    • Klon, A. E., Glick, M., and Davies, J.W. (2004) Application of machine learning to improve the results of high-throughput docking against the HIV-1 protease. J. Chem. Inf. Comput. Sci. 44, 2216–2224.
    • (2004) J. Chem. Inf. Comput. Sci. , vol.44 , pp. 2216-2224
    • Klon, A.E.1    Glick, M.2    Davies, J.W.3
  • 6
    • 33646249968 scopus 로고    scopus 로고
    • Newmethods for ligand-based virtual screening: Use of data fusion and machine learning to enhance the effectiveness of similarity searching
    • Hert, J., Willett, P., Wilton, D. J., Acklin, P., Azzaoui, K., Jacoby, E., and Schuffenhauer, A. (2006)Newmethods for ligand-based virtual screening: use of data fusion and machine learning to enhance the effectiveness of similarity searching. J. Chem. Inf. Model. 46, 462–470.
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 462-470
    • Hert, J.1    Willett, P.2    Wilton, D.J.3    Acklin, P.4    Azzaoui, K.5    Jacoby, E.6    Schuffenhauer, A.7
  • 7
    • 26944446576 scopus 로고    scopus 로고
    • Keynote review: In vitro safety pharmacology profiling: An essential tool for successful drug development
    • Whitebread, S., Hamon, J., Bojanic, D., and Urban, L. (2005) Keynote review: in vitro safety pharmacology profiling: an essential tool for successful drug development. Drug Discov. Today 10, 1421–1433.
    • (2005) Drug Discov. Today , vol.10 , pp. 1421-1433
    • Whitebread, S.1    Hamon, J.2    Bojanic, D.3    Urban, L.4
  • 11
    • 40049100210 scopus 로고    scopus 로고
    • Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure
    • Bender, A., Scheiber, J., Glick, M., Davies, J. W., Azzaoui, K., Hamon, J., Urban, L., Whitebread, S., and Jenkins, J. L. (2007) Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure. ChemMed-Chem 2, 861–873.
    • (2007) Chemmed-Chem , vol.2 , pp. 861-873
    • Bender, A.1    Scheiber, J.2    Glick, M.3    Davies, J.W.4    Azzaoui, K.5    Hamon, J.6    Urban, L.7    Whitebread, S.8    Jenkins, J.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.