Controlled-release effervescent floating matrix tablets of ciprofloxacin hydrochloride: Development, optimization and in vitro-in vivo evaluation in healthy human volunteers

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 74, Issue 2, 2010, Pages 332-339

  Tadros, Mina Ibrahim ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Abdominal X ray imaging; Ciprofloxacin hydrochloride; Floating gastroretentive tablets; Gas former; Release retarding polymers

Indexed keywords

ALGINIC ACID; BARIUM SULFATE; BICARBONATE; CALCIUM CARBONATE; CIPROFLOXACIN; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER;

ABDOMINAL RADIOGRAPHY; ADULT; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG RETENTION; DRUG STABILITY; EFFERVESCENT TABLET; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PHYSICAL CHEMISTRY; STORAGE TEMPERATURE; SUSTAINED DRUG RELEASE; TABLET ADHESION; TABLET FLOATING; TABLET FORMULATION; TABLET FRIABILITY; TABLET PROPERTY; TABLET SWELLING;

ADULT; ALGINATES; BARIUM SULFATE; CALCIUM CARBONATE; CIPROFLOXACIN; CONTRAST MEDIA; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG STABILITY; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; MALE; METHYLCELLULOSE; PHYSICOCHEMICAL PHENOMENA; RADIOGRAPHY, ABDOMINAL; SODIUM BICARBONATE; STOMACH; TABLETS; TIME FACTORS;

EID: 75449103933     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.11.010     Document Type: Article

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