메뉴 건너뛰기




Volumn 19, Issue 5, 2004, Pages 750-752

A case report of a poor metabolizer of CYP2D6 presented with unusual responses to nortriptyline medication

Author keywords

Adverse effects; Cytochrome P 450 CYP2D6; Nortriptyline; Pharmacogenetics

Indexed keywords

CYTOCHROME P450 2D6; LORAZEPAM; NORTRIPTYLINE; RISPERIDONE;

EID: 7544234883     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2004.19.5.750     Document Type: Article
Times cited : (8)

References (15)
  • 1
    • 0027375143 scopus 로고
    • Pharmacokinetics of antidepressants: Why and how they are relevant to treatment
    • Preskorn SH. Pharmacokinetics of antidepressants: why and how they are relevant to treatment. J Clin Psychiatry 1993; 54: 14-34.
    • (1993) J Clin Psychiatry , vol.54 , pp. 14-34
    • Preskorn, S.H.1
  • 2
    • 0031943396 scopus 로고    scopus 로고
    • Standards of laboratory practice: Antidepressant drug monitoring
    • Linder MW, Keck PE Jr. Standards of laboratory practice: antidepressant drug monitoring. Clin Chem 1998; 44: 1073-84.
    • (1998) Clin Chem , vol.44 , pp. 1073-1084
    • Linder, M.W.1    Keck Jr., P.E.2
  • 3
    • 0034115770 scopus 로고    scopus 로고
    • Steady state plasma levels of nortriptyline and its hydroxylated metabolites in Japanese patients: Impact of CYP2D6 genotype on the hydroxylation of nortriptyline
    • Morita S, Shimoda K, Someya T, Yoshimura Y, Kamijima K, Kato N. Steady state plasma levels of nortriptyline and its hydroxylated metabolites in Japanese patients: Impact of CYP2D6 genotype on the hydroxylation of nortriptyline. J Clin Psychopharmacol 2000; 20: 141-9.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 141-149
    • Morita, S.1    Shimoda, K.2    Someya, T.3    Yoshimura, Y.4    Kamijima, K.5    Kato, N.6
  • 4
    • 0036204756 scopus 로고    scopus 로고
    • Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs
    • Bertilsson L, Dahl ML, Dalen P, Al-Shurbaji A. Molecular genetics of CYP2D6: Clinical relevance with focus on psychotropic drugs. Br J Clin Pharmacol 2002; 53: 111-22.
    • (2002) Br J Clin Pharmacol , vol.53 , pp. 111-122
    • Bertilsson, L.1    Dahl, M.L.2    Dalen, P.3    Al-Shurbaji, A.4
  • 5
    • 0029926315 scopus 로고    scopus 로고
    • Steady-state plasma levels of nortriptyline and its 10-hydroxy metabolite: Relationship to the CYP2D6 genotype
    • Dahl ML, Bertilsson L, Nordin C. Steady-state plasma levels of nortriptyline and its 10-hydroxy metabolite: relationship to the CYP2D6 genotype. Psychopharmacology 1996; 123: 315-9.
    • (1996) Psychopharmacology , vol.123 , pp. 315-319
    • Dahl, M.L.1    Bertilsson, L.2    Nordin, C.3
  • 6
    • 0031949132 scopus 로고    scopus 로고
    • W-hydroxylation of nortriptyline in white persons with 0, 1, 2, 3 and 13 functional CYP2D6 genes
    • Dalen P, Dahl ML, Ruiz ML, Nordin J, Bertilsson L. W-hydroxylation of nortriptyline in white persons with 0, 1, 2, 3 and 13 functional CYP2D6 genes. Clin Pharmacol Ther 1998; 63: 444-52.
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 444-452
    • Dalen, P.1    Dahl, M.L.2    Ruiz, M.L.3    Nordin, J.4    Bertilsson, L.5
  • 7
    • 0019450472 scopus 로고
    • Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: Clinical implications: letter
    • Bertilsson L, Mellstrorn B, Sjokvist F, Martension B, Asberg M. Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: clinical implications: letter. Lancet 1981; 1: 560-1.
    • (1981) Lancet , vol.1 , pp. 560-561
    • Bertilsson, L.1    Mellstrorn, B.2    Sjokvist, F.3    Martension, B.4    Asberg, M.5
  • 8
    • 0024796958 scopus 로고
    • The human debrisoquine 4-hydroxylase (CYP2D) locus: Sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene
    • Kimura S, Umeno M, Skoda RC, Meyer UA, Gonzalez FJ. The human debrisoquine 4-hydroxylase (CYP2D) locus: sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene. Am J Hum Genet 1989; 45: 889-94.
    • (1989) Am J Hum Genet , vol.45 , pp. 889-894
    • Kimura, S.1    Umeno, M.2    Skoda, R.C.3    Meyer, U.A.4    Gonzalez, F.J.5
  • 9
    • 0033871198 scopus 로고    scopus 로고
    • Rapid detection of the CYP2D6*3, CYP2D6*4, CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR
    • Hersberger M, Marti-Jaun J, Rentsch K, Hanseler E. Rapid detection of the CYP2D6*3, CYP2D6*4, CYP2D6*6 alleles by tetra-primer PCR and of the CYP2D6*5 allele by multiplex long PCR. Clin Chem 2000; 46: 1072-7.
    • (2000) Clin Chem , vol.46 , pp. 1072-1077
    • Hersberger, M.1    Marti-Jaun, J.2    Rentsch, K.3    Hanseler, E.4
  • 10
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002; 3: 229-43.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 11
    • 0034094251 scopus 로고    scopus 로고
    • Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan o-demethylation in different CYP2D6 genotypes
    • Kubota T, Yamaura Y, Ohkawa N, Hara H, Chiba K. Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan o-demethylation in different CYP2D6 genotypes. Br J Clin Pharmacol 2000; 50: 31-4.
    • (2000) Br J Clin Pharmacol , vol.50 , pp. 31-34
    • Kubota, T.1    Yamaura, Y.2    Ohkawa, N.3    Hara, H.4    Chiba, K.5
  • 14
    • 0034913055 scopus 로고    scopus 로고
    • An evaluation of risperidone drug interactions
    • DeVane CL, Nemeroff CB. An evaluation of risperidone drug interactions. J Clin Psychopharmacol 2001; 21: 408-16.
    • (2001) J Clin Psychopharmacol , vol.21 , pp. 408-416
    • DeVane, C.L.1    Nemeroff, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.