Beneficial effect of trimebutine and N-monodesmethyl trimebutine on trinitrobenzene sulfonic acid-induced colitis in rats

Life Sciences

Volumn 76, Issue 3, 2004, Pages 319-329

  Chevalier, Eric ^a,b   Pétoux, Francine ^a   Chovet, Maria ^a   Langlois, Annik ^a  

^a PFIZER INC   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Colitis; Local anesthetics; Rats; Trimebutine; Trinitrobenzene sulfonic acid

Indexed keywords

ALCOHOL; BUPIVACAINE; DIGESTIVE TRACT SPASMOLYTIC AGENT; LIDOCAINE; N NORTRIMEBUTINE; TRIMEBUTINE; TRINITROBENZENESULFONIC ACID; UNCLASSIFIED DRUG;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLITIS; CONTROLLED STUDY; DISSOLUTION; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFECT; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; HYPEREMIA; MALE; NECROSIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN WEIGHT; RAT; STATISTICAL SIGNIFICANCE;

ADMINISTRATION, RECTAL; ANESTHETICS, LOCAL; ANIMALS; BUPIVACAINE; COLITIS; COLON; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL AGENTS; INJECTIONS, SUBCUTANEOUS; LIDOCAINE; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; TRIMEBUTINE; TRINITROBENZENESULFONIC ACID;

ORYCTOLAGUS CUNICULUS;

EID: 7544226557     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.08.011     Document Type: Article

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