Renal toxicity of ethylene glycol results from internalization of calcium oxalate crystals by proximal tubule cells

Toxicology Letters

Volumn 192, Issue 3, 2010, Pages 365-372

  Hovda, Knut Erik ^a,b   Guo, Chungang ^a   Austin, Ronald ^c   McMartin, Kenneth E ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^c Louisiana State University Health Sciences Center   (United States)

Author keywords

Ethylene glycol poisoning; Hyperoxaluria; Kidney stones; Mitochondria; Nephrotoxicity; Oxalate crystals

Indexed keywords

CALCIUM OXALATE; ETHYLENE GLYCOL;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FISCHER 344 RAT; HUMAN; HUMAN CELL; HYPEROXALURIA; INTERNALIZATION; KIDNEY PROXIMAL TUBULE; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSMISSION ELECTRON MICROSCOPY; WISTAR RAT;

ANIMALS; CALCIUM OXALATE; CELL DEATH; CELLS, CULTURED; ETHYLENE GLYCOL; HUMANS; KIDNEY; KIDNEY TUBULES, PROXIMAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, ELECTRON; RATS; RATS, INBRED F344; RATS, WISTAR;

RATTUS;

EID: 75349112039     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.11.013     Document Type: Article

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