Hepatic mRNA expression of histone (H3): An early predictor of tumorgenic changes in chronic hepatitis C

Archives of Medical Science

Volumn 5, Issue 4, 2009, Pages 506-512

  El Bassiouny, Azza ^a   Abou Shousha, Tarek ^b   Moussa, Mona ^b   El Ahwany, Eman ^a   El Bassiouni, Nora ^b   Maher, Kesmat ^a   Galli, Ayman ^c   Youssef, Magdy ^c   Zada, Suher ^d  

^a Giza   (Egypt)

^b Imbaba   (Egypt)

^c THEODOR BILHARZ RESEARCH INSTITUTE   (Egypt)

^d The American University in Cairo   (Egypt)

Author keywords

Chronic hepatitis C; Hepatocellular carcinoma; Histone (H3); In situ hybridization

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; HISTONE H3; MESSENGER RNA;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD SAMPLING; CELL CYCLE; CELL NUCLEUS; CLINICAL ARTICLE; CYTOPLASM; FEMALE; GENE EXPRESSION; HEPATITIS C; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; LIVER; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER FIBROSIS; MALE; PREDICTION;

EID: 75349104022     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Parkin D, Bray F, Ferlay J, Pisani P. Estimating the word cancer burden: Globocan 2000. Int J Cancer 2000; 94: 153-6.
2. Lee JS, Chu IS, Heo J, et al. Classification and prediction of survival in hepatocellular carcinoma carcinomas by gene expression profiling. Hematology 2004; 40: 667-76.
3. Thorgeirsson SS, Grisham JW. Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 2002; 31: 339-46.
4. Yoon SK. Recent advances in tumor markers of human hepatocellular carcinoma. Intervirology 2008; 51 Suppl. 1: 34-41.
5. Hayashi J, Aoki H, Kajina K, et al. Hepatitis C virus core protein activates the MAPK/ERR cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha. Hepatology 32: 958-961.
6. Lee JS, Thorgeirsson SS. Functional and genomic implications of global gene expression profiles in cell lines from human hepatocellular cancer. Hepatology 2002; 35: 1134-43.
7. Parkin D. Global cancer statistics in the year 2000. Lancet Oncol 2002; 2: 533-43.
8. Chen N, Bai L, Li L, et al. Apoptosis pathway of liver cells in chronic hepatitis. World J Gastroenterol 2004; 10: 3201-4.
9. Van Hooser A, Goodrich DW, Allis CD, et al. Histone H3 phosphorylation is required for the initiation but not maintenance of mammalian chromosome condensation. J Cell Sci 1998; 111: 3497-506.
10. Prigent C, Dimitrov S. Phosphorylation of serine so in histone H3, what for? J Cell Sci 2003; 166: 3677-85.
11. Liu YH, Pei RJ, Cheng CC, et al. HCC CKs are altered histones during tumor transformation in hepatoma. Res Commun Mol Pathol Pharmacol 2002; 112: 27-38.
12. Togashi T, Obata M, Aoyagi Y, et al. Two distinct methods analysing chromatin structure using centrifugation and antibodies to modified histone H3: Both provide similaire chromatin states of the Rit 1/bcl 116 gene. Mol Cell Biol 2004; 22: 8215-25.
13. Chadee DN, Hendzel MJ, Tylipski CP, et al. Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J Biol Chem 1999; 274: 24914-20.
14. Choy JS, Kron SJ. NuA4 subunit YngG2 function in intra S-phase DNA damage response. Mol Cell Biol 2002; 22: 8215-25.
15. Timmermann S, Lehrmann H, Polesskaya A, Harel-Bellan A. Histone acetylation and diseases. Cell Moll Life Sci 2001; 58: 728-36.
16. Kim DH, Kim M, Kwon HJ. Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. J Biochem Mol Biol 2003; 38: 110-9.
17. Yamashita Y, Shimada M, Harimato N, et al. Histone deacetylase inhibitor trichostatin induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells. Int J Cancer 2003; 103: 572-6.
18. Emanuele S, Lauricella M, Tesoriere G. Histone deacetylase inhibitors: apoptotic effects and clinical implications. Int J Oncol 2008; 33: 637-46.
19. Sakamoto R, Nitta T, Kamikawa Y, et al. The assessment of cell proliferation during 9, 10-dimethyl-1, benzanthracence-induced hamster-tongue carcinogenesis by means of histone H3mRNA in situ hybridization. Med Electron Microsc 2004; 37: 52-61.
20. Murakami M, Mizoguchi Y, Horibe Y, et al. In situ localization of S-phase specific histone (H3) mRNA in Bowen's disease. APMIS 1999; 107: 1005-12.
21. Spencer VA, Davie JR. Signal transduction pathways and chromatin structure in cancer cells. J Cell Biochem Suppl 2000; 35: 27-35.
22. Gown AM, Jiang JJ, Matles H, et al. Validation of S-phase specificity of histone (H3), in situ hybridization in normal and malignant cells. J Histochem Cytochem 1996; 44: 221-6.
23. Arakura N, Hayama M, Honda T, et al. Histone H3 mRNA in situ hybridization for identifying proliferating cells in human pancreas, with special references to the ductal system. Histochem J 2001; 3: 183-91.
24. World Medical Association. Declaration of Helsinki: ethical principles for medical research involving human subjects. Available at: http://www.wma.net/e/policy/pdf/17c.pdf Accessed September 4, 2008.
25. Saber M, Omar M, Badwai H, Romeih M. Comparative studies in serological diagnosis of hepatitis C virus infection. J Hepatol Gastroenterol Inf Dis 1995; 3: 47-51.
26. The French METAVIR Cooperative Study Group. Intraobserver and interobserver variations in liver biopsy interpretation in patients with chronic hepatitis C. Hepatology 1994; 20: 15-20.
27. Ishak KG. Virus interference: The interferon. Proc R Soc Lond B Biol Sci 1994; 147: 258-267.
28. Maeyama H, Furuwatari C, Ota H, Akamatsu T, Nakayama J, Katsuyama T. Histone H3 messenger RNA in situ hybridization for identifying proliferating cells in formalinfixed rat gastric mucosa. Histochem J 1997; 29: 867-73.
29. Nagao T, Inshida Y, Kondo Y. Determination of S-phase cells by in situ hybridization for histore H3 mRNA in hepatocellular carcinoma: Correlation with histologic grade and other cell proliferative markers. Mod Pathol 1996; 9: 99-104.
30. Maurer HR. Potential pitfalls of (3H) thymidine technique to measure cell proliferation. Cell Tissue Kinetics 1981; 14: 111-20.
31. Venturi A, Piaz FD, Giovannini C, Gramantieri L, Chieco P, Bolondi L. Human hepatocellular carcinoma expresses specific PCNA isoforms: An in vivo and in vitro evaluation. Lab Invest 2008; 88: 995-1007.
32. Morris GF, Mathews MB. Regulation of proliferating cell nuclear antigen during the cell cycle. J Biol Chem 1989; 264: 13856-64.
33. Coltera MD, Gown AM. PCNA/Cyclin expression and Brdu uptake define different subpopulations in different cell lines. J Histochem Cytochem 1991; 39: 23-30.
34. Bravo R, Macdonald-Bravo H. Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: Association with DNA replication sites. J Cell Biol 1987; 105: 1549-54.
35. Chou MY, Chang AL, McBride J, Donoff B, Gallagher GT, Wong DT. A rapid method to determine proliferation patterns of normal and malignant tissues by H3 mRNA in situ hybridization. Am J Pathol 1990; 136: 729-33.
36. Rautiainen E, Haapasalo H, Sallinen P, Rantala I, Helen P, Helin H. Histone mRNA in situ hybridization in astrocytomas: A comparison with PCNA, MIB-1 and mitosis in paraffin-embedded material. Histopathology 1998; 32: 43-50.
37. Shrumperli D. Cell-cycle regulation of histone gene expression. Cell 1986; 45: 471-2.
38. Heintz N, Sive H, Roeder R. Regulation of human histone gene expression: Kinetics of accumulation and changes in the rate of synthesis and in the half- lives of individual histone mRNA during the HeLa cell cycle. Mol Cell Biol 1993; 3: 539-50.
39. Stenger JE, Mayr GA, Mann K, Tegtmeyer P. Formation of stable P53 homotetramer and multiples of tetramers. Mol Carcinog 1992; 5: 102-6.
40. Butterworth B, Goldsworthy T. The role of cell proliferation in multistage carcinogenesis. Proc Soc Exp Biol Med 1991; 198: 683-7.
41. Marks F, Fürstenberger G, Müller-Decker K. Tumor promotion as a target of cancer prevention. Rec Results Cancer Res 2007; 174: 37-47.
42. Beerman H, Smit VT, Kluin PM, et al. Flow cytometric analysis of DNA stem line heterogeneity in primary and metastasis breast cancer. Cytometry 1991; 12: 147-54.
43. Kaketani K, Saito T, Kuwahara A, et al. DNA stem line heterogeneity in esophageal cancer accurately identified by flow cytometric analysis. Cancer 1993; 72: 3564-70.
44. Kucuk O, Demirer T, Gilman-Sachs A, et al. Intratumor heterogeneity of DNA ploidy and correlations with clinical stage and histologic grade in prostate cancer. J Surg Oncol 1993; 54: 171-4.
45. Campani D, Boggi U, Cecchetti D, et al. P53 over expression in lymph node metastases predicts clinical outcome in ductal pancreatic cancer. Pancreas 1999; 19: 26-32.