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Volumn 5, Issue 4, 2009, Pages 242-249

Case files of the medical toxicology fellowship at Banner good samaritan medical center in Phoenix, AZ: A non-warfarin anticoagulant overdose

Author keywords

Adp antagonists; Factor Xa inhibitors; Low molecular weight heparins; Overdose

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE RECEPTOR BLOCKING AGENT; ANTICOAGULANT AGENT; APROTININ; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 10A INHIBITOR; BLOOD CLOTTING FACTOR 5 LEIDEN; CLOPIDOGREL; DABIGATRAN; DALTEPARIN; DESMOPRESSIN; ENOXAPARIN; FONDAPARINUX; HEPARIN; IDRAPARINUX; LOW MOLECULAR WEIGHT HEPARIN; MELAGATRAN; PLACEBO; PROTAMINE SULFATE; RECOMBINANT BLOOD CLOTTING FACTOR 7A; RIVAROXABAN; SALICYLIC ACID DERIVATIVE; THIENOPYRIDINE DERIVATIVE; THROMBIN INHIBITOR; TICAGRELOR; TICLOPIDINE; TISSUE PLASMINOGEN ACTIVATOR; WARFARIN; XIMELAGATRAN; BLOOD CLOTTING FACTOR 5;

EID: 75349093047     PISSN: 15569039     EISSN: 19376995     Source Type: Journal    
DOI: 10.1007/BF03178275     Document Type: Article
Times cited : (10)

References (56)
  • 2
    • 0036014077 scopus 로고    scopus 로고
    • Therapeutic equivalency of low-molecular-weight heparins
    • McCart GM, Kayser SR. Therapeutic equivalency of low-molecular-weight heparins. Ann Pharmacother. 2002;36:1042-1057.
    • (2002) Ann Pharmacother , vol.36 , pp. 1042-1057
    • McCart, G.M.1    Kayser, S.R.2
  • 3
    • 2942641718 scopus 로고    scopus 로고
    • Platelet ADP receptor antagonists: Ticlopidine and clopidogrel
    • Jacobson AK. Platelet ADP receptor antagonists: ticlopidine and clopidogrel. Best Pract Res Clin Haematol. 2004;17:55-64.
    • (2004) Best Pract Res Clin Haematol , vol.17 , pp. 55-64
    • Jacobson, A.K.1
  • 4
    • 34047123414 scopus 로고    scopus 로고
    • ADP receptor antagonism: What's in the pipeline
    • Angiolillo DJ. ADP receptor antagonism: what's in the pipeline. Am J Cardiovasc Drugs. 2007;7:423-432.
    • (2007) Am J Cardiovasc Drugs , vol.7 , pp. 423-432
    • Angiolillo, D.J.1
  • 6
    • 33947426099 scopus 로고    scopus 로고
    • Clopidogrel: A review of its use in the prevention of thrombosis
    • Plosker GL, Lyseng-Williamson KA. Clopidogrel: A review of its use in the prevention of thrombosis. Drugs. 2007;67:613-646.
    • (2007) Drugs , vol.67 , pp. 613-646
    • Plosker, G.L.1    Lyseng-Williamson, K.A.2
  • 7
    • 0032879820 scopus 로고    scopus 로고
    • Ticlopidine and clopidogrel
    • Quinn MJ, Fitzgerald DJ. Ticlopidine and clopidogrel. Circulation. 1999;100:1667-1672.
    • (1999) Circulation , vol.100 , pp. 1667-1672
    • Quinn, M.J.1    Fitzgerald, D.J.2
  • 8
    • 77949999451 scopus 로고    scopus 로고
    • Ticlid [package insert], NJ: Roche Laboratories Inc.
    • Ticlid [package insert]. Nutley, NJ: Roche Laboratories Inc.; 2001.
    • (2001) Nutley
  • 9
    • 46649089410 scopus 로고    scopus 로고
    • Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents
    • Abuzahra M, Pillai M, Caldera A, et al. Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents. Am J Cardiol. 2008;102:401-403.
    • (2008) Am J Cardiol , vol.102 , pp. 401-403
    • Abuzahra, M.1    Pillai, M.2    Caldera, A.3
  • 10
    • 0032777985 scopus 로고    scopus 로고
    • Single dose pharmaco-dynamics of clopidogrel
    • Thebault JJ, Kieffer G, Cariou R. Single dose pharmaco-dynamics of clopidogrel. Semin Thromb Hemost. 1999;25 (Suppl 2):3-8.
    • (1999) Semin Thromb Hemost , vol.25 , Issue.SUPPL. 2 , pp. 3-8
    • Thebault, J.J.1    Kieffer, G.2    Cariou, R.3
  • 12
    • 0033817335 scopus 로고    scopus 로고
    • Comparative pharmaco-kinetics of LMWHs
    • Samama MM, Gerotziafas GT. Comparative pharmaco-kinetics of LMWHs. Semin Thromb Hemost. 2000;26(Suppl 1): 31-38.
    • (2000) Semin Thromb Hemost , vol.26 , Issue.SUPPL. 1 , pp. 31-38
    • Samama, M.M.1    Gerotziafas, G.T.2
  • 13
    • 33749481451 scopus 로고    scopus 로고
    • Use of low-molecular-weight heparin to bridge therapy in obese patients and in patients with renal dysfunction
    • George-Phillips KL, Bungard TJ. Use of low-molecular-weight heparin to bridge therapy in obese patients and in patients with renal dysfunction. Pharmacotherapy. 2006;26:1479-1490.
    • (2006) Pharmacotherapy , vol.26 , pp. 1479-1490
    • George-Phillips, K.L.1    Bungard, T.J.2
  • 14
    • 23944524771 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: Clinical manifestations and management strategies
    • Menajovsky LB. Heparin-induced thrombocytopenia: clinical manifestations and management strategies. Am J Med. 2005; 118(Suppl 8A):21S-30S.
    • (2005) Am J Med , vol.118 , Issue.SUPPL. 8A
    • Menajovsky, L.B.1
  • 15
    • 0036861746 scopus 로고    scopus 로고
    • Fondaparinux: A new antithrombotic agent
    • Cheng JW. Fondaparinux: A new antithrombotic agent. Clin Ther. 2002;24:1757-1769.
    • (2002) Clin Ther , vol.24 , pp. 1757-1769
    • Cheng, J.W.1
  • 16
    • 0036330282 scopus 로고    scopus 로고
    • Fondaparinux sodium
    • Keam SJ, Goa KL. Fondaparinux sodium. Drugs. 2002;62: 1673-1685.
    • (2002) Drugs , vol.62 , pp. 1673-1685
    • Keam, S.J.1    Goa, K.L.2
  • 17
    • 41749116871 scopus 로고    scopus 로고
    • Heparins, low-molecular-weight heparins, and pentasaccharides: Use in the older patient
    • Dinwoodey DL, Ansell JE. Heparins, low-molecular-weight heparins, and pentasaccharides: use in the older patient. Cardiol Clin. 2008;26:145-155.
    • (2008) Cardiol Clin , vol.26 , pp. 145-155
    • Dinwoodey, D.L.1    Ansell, J.E.2
  • 18
  • 19
    • 55249089038 scopus 로고    scopus 로고
    • New anticoagulants
    • Bauer KA. New anticoagulants. Curr Opin Hematol. 2008;15: 509-515.
    • (2008) Curr Opin Hematol , vol.15 , pp. 509-515
    • Bauer, K.A.1
  • 22
    • 0035283092 scopus 로고    scopus 로고
    • A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement
    • Turpie AG, Gallus AS, Hoek JA, et al. A synthetic pentasaccharide for the prevention of deep-vein thrombosis after total hip replacement. N Engl J Med. 2001;344:619-625.
    • (2001) N Engl J Med , vol.344 , pp. 619-625
    • Turpie, A.G.1    Gallus, A.S.2    Hoek, J.A.3
  • 23
    • 77949941657 scopus 로고    scopus 로고
    • Arixtra [package insert]. Research Triangle Park, NC: GlaxoSmith Kline; October 2008
    • Arixtra [package insert]. Research Triangle Park, NC: GlaxoSmith Kline; October 2008.
  • 24
    • 65249174996 scopus 로고    scopus 로고
    • The direct factor Xa inhibitor rivaroxaban
    • Verma AK, Brighton TA. The direct factor Xa inhibitor rivaroxaban. Med J Aust. 2009;190:379-383.
    • (2009) Med J Aust , vol.190 , pp. 379-383
    • Verma, A.K.1    Brighton, T.A.2
  • 26
    • 4644308426 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • Hirsh J. Raschke R. Heparin and low-molecular-weight heparin: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(Suppl 3):188-203S.
    • (2004) Chest , vol.126 , Issue.SUPPL. 3
    • Hirsh, J.1    Raschke, R.2
  • 27
    • 0031680310 scopus 로고    scopus 로고
    • College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: The clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban
    • Laposata M, Green D, Van Cott EM, et al. College of American Pathologists Conference XXXI on laboratory monitoring of anticoagulant therapy: the clinical use and laboratory monitoring of low-molecular-weight heparin, danaparoid, hirudin and related compounds, and argatroban. Arch Pathol Lab Med. 1998;122:799-807.
    • (1998) Arch Pathol Lab Med , vol.122 , pp. 799-807
    • Laposata, M.1    Green, D.2    van Cott, E.M.3
  • 28
    • 34250006279 scopus 로고    scopus 로고
    • Reversal of anti-thrombin activity using protamine sulfate. Experience in a neonate with a 10-fold overdose of enoxaparin
    • Wiernikowski JT, Chan A, Lo G. Reversal of anti-thrombin activity using protamine sulfate. Experience in a neonate with a 10-fold overdose of enoxaparin. Thromb Res. 2007;120:303-305.
    • (2007) Thromb Res , vol.120 , pp. 303-305
    • Wiernikowski, J.T.1    Chan, A.2    Lo, G.3
  • 29
    • 12144287441 scopus 로고    scopus 로고
    • Evaluation of a novel point-of-care enoxaparin monitor with central laboratory anti-Xa levels
    • Saw J, Kereiakes DJ, Mahaffey KW, et al. Evaluation of a novel point-of-care enoxaparin monitor with central laboratory anti-Xa levels. Thromb Res. 2003;112:301-306.
    • (2003) Thromb Res , vol.112 , pp. 301-306
    • Saw, J.1    Kereiakes, D.J.2    Mahaffey, K.W.3
  • 30
    • 52049127027 scopus 로고    scopus 로고
    • Use of a single anti-Xa calibration curve is adequate for monitoring enoxaparin and tinzaparin levels in children
    • Robertson JD, Brandao L, Williams S, et al. Use of a single anti-Xa calibration curve is adequate for monitoring enoxaparin and tinzaparin levels in children. Thromb Res. 2008;122:867-869.
    • (2008) Thromb Res , vol.122 , pp. 867-869
    • Robertson, J.D.1    Brandao, L.2    Williams, S.3
  • 31
    • 0025996472 scopus 로고
    • Identification of risk factors for bleeding during treatment of acute venous thromboembolism with heparin or low molecular weight heparin
    • Nieuwenhuis HK, Albada J, Banga JD, et al. Identification of risk factors for bleeding during treatment of acute venous thromboembolism with heparin or low molecular weight heparin. Blood. 1991;78:2337-2343.
    • (1991) Blood , vol.78 , pp. 2337-2343
    • Nieuwenhuis, H.K.1    Albada, J.2    Banga, J.D.3
  • 32
    • 19644366172 scopus 로고    scopus 로고
    • Monitoring clopidogrel action: Comparison of methods
    • Geiger J, Teichmann L, Grossman R, et al. Monitoring clopidogrel action: comparison of methods. Clin Chem. 2005;51: 957-965.
    • (2005) Clin Chem , vol.51 , pp. 957-965
    • Geiger, J.1    Teichmann, L.2    Grossman, R.3
  • 33
    • 33845474736 scopus 로고    scopus 로고
    • Monitoring platelet inhibition after clopidogrel with the Verify Now-P2Y12 rapid analyzer: The VERify Thrombosis Risk Assessment (VERITAS) study
    • Malinin A, Pokov A, Spergling M, et al. Monitoring platelet inhibition after clopidogrel with the Verify Now-P2Y12 rapid analyzer: The VERify Thrombosis Risk Assessment (VERITAS) study. Thromb Res. 2007;119:277-284.
    • (2007) Thromb Res , vol.119 , pp. 277-284
    • Malinin, A.1    Pokov, A.2    Spergling, M.3
  • 34
    • 8344231455 scopus 로고    scopus 로고
    • Aspirin and clopidogrel: Efficacy, safety, and the issue of drug resistance
    • Cattaneo M. Aspirin and clopidogrel: Efficacy, safety, and the issue of drug resistance. Arterioscler Thromb Vasc Biol. 2004;24:1980-1987.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1980-1987
    • Cattaneo, M.1
  • 35
    • 77949985111 scopus 로고    scopus 로고
    • Plavix [package insert]. Bridgewater, NJ: Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2008
    • Plavix [package insert]. Bridgewater, NJ: Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership; 2008.
  • 36
    • 38549135088 scopus 로고    scopus 로고
    • Determination of clopidogrel main metabolite in plasma: A useful tool for monitoring therapy?
    • Mani H, Toennes SW, Linnemann B, et al. Determination of clopidogrel main metabolite in plasma: a useful tool for monitoring therapy? Ther Drug Monit. 2008;30:84-89.
    • (2008) Ther Drug Monit , vol.30 , pp. 84-89
    • Mani, H.1    Toennes, S.W.2    Linnemann, B.3
  • 37
    • 1642453779 scopus 로고    scopus 로고
    • Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance
    • Lau WC, Gurbel PA, Watkins PB. Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance. Circulation. 2004;109:166-171.
    • (2004) Circulation , vol.109 , pp. 166-171
    • Lau, W.C.1    Gurbel, P.A.2    Watkins, P.B.3
  • 38
    • 0035120357 scopus 로고    scopus 로고
    • Novel platelet inhibitors
    • Bennett JS. Novel platelet inhibitors. Annu Rev Med. 2001;52:161-184.
    • (2001) Annu Rev Med , vol.52 , pp. 161-184
    • Bennett, J.S.1
  • 39
    • 1642586936 scopus 로고    scopus 로고
    • An approach to estimation of the risk of TTP during clopidogrel therapy
    • Jonas S, Grieco G. An approach to estimation of the risk of TTP during clopidogrel therapy. Stroke. 2004;35:537-538.
    • (2004) Stroke , vol.35 , pp. 537-538
    • Jonas, S.1    Grieco, G.2
  • 41
    • 2642587584 scopus 로고    scopus 로고
    • Incomplete reversal of enoxaparin toxicity by protamine: Implications of renal insufficiency, obesity, and low molecular weight heparin sulfate content
    • Chawla LS, Moore G, Seneff MG. Incomplete reversal of enoxaparin toxicity by protamine: implications of renal insufficiency, obesity, and low molecular weight heparin sulfate content. Obes Surg. 2004;14:695-698.
    • (2004) Obes Surg , vol.14 , pp. 695-698
    • Chawla, L.S.1    Moore, G.2    Seneff, M.G.3
  • 42
    • 34247866342 scopus 로고    scopus 로고
    • Recombinant activated factor VII treatment of retroperitoneal hematoma in a patient with renal failure receiving enoxaparin and clopidogrel
    • Cherfan A, Arabi Y, Al Askar A, et al. Recombinant activated factor VII treatment of retroperitoneal hematoma in a patient with renal failure receiving enoxaparin and clopidogrel. Pharmacotherapy. 2007;27:755-759.
    • (2007) Pharmacotherapy , vol.27 , pp. 755-759
    • Cherfan, A.1    Arabi, Y.2    Al Askar, A.3
  • 43
    • 22844447645 scopus 로고    scopus 로고
    • Life-threatening abdominal wall hematoma in a chronic renal failure patient after a single dose of enoxaparin
    • Weinsheimer RL, Libby E, Howdieshell TR. Life-threatening abdominal wall hematoma in a chronic renal failure patient after a single dose of enoxaparin. Am Surg. 2005;71:132-134.
    • (2005) Am Surg , vol.71 , pp. 132-134
    • Weinsheimer, R.L.1    Libby, E.2    Howdieshell, T.R.3
  • 44
    • 0037243921 scopus 로고    scopus 로고
    • The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments
    • Kam PCA, Nethery CM. The thienopyridine derivatives (platelet adenosine diphosphate receptor antagonists), pharmacology and clinical developments. Anaesthesia. 2003;58: 28-35.
    • (2003) Anaesthesia , vol.58 , pp. 28-35
    • Kam, P.C.A.1    Nethery, C.M.2
  • 45
    • 38449097926 scopus 로고    scopus 로고
    • The anticoagulated patient: Strategies for effective blood loss management
    • Levy JH, Tanaka KA. The anticoagulated patient: strategies for effective blood loss management. Surgery. 2007;142: S71-S77.
    • (2007) Surgery , vol.142
    • Levy, J.H.1    Tanaka, K.A.2
  • 46
    • 0022588789 scopus 로고
    • Endothelial stimulation by DDAVP in von Willebrand's disease and haemophilia
    • Greer IA, McLaren M, Belch JJ, et al. Endothelial stimulation by DDAVP in von Willebrand's disease and haemophilia. Haemostasis. 1986;16:15-19.
    • (1986) Haemostasis , vol.16 , pp. 15-19
    • Greer, I.A.1    McLaren, M.2    Belch, J.J.3
  • 47
    • 0020523381 scopus 로고
    • DDAVP: Does the drug have a direct effect on the vessel wall?
    • Barnhart MI, Chen S, Lusher JM. DDAVP: does the drug have a direct effect on the vessel wall? Thromb Res. 1983; 31:239-253.
    • (1983) Thromb Res , vol.31 , pp. 239-253
    • Barnhart, M.I.1    Chen, S.2    Lusher, J.M.3
  • 48
    • 47849084572 scopus 로고    scopus 로고
    • Effects of desmopressin on platelet membrane glycoproteins and platelet aggregation in volunteers on clopidogrel
    • Leithauser B, Zielske D, Seyfert UT, et al. Effects of desmopressin on platelet membrane glycoproteins and platelet aggregation in volunteers on clopidogrel. Clin Hemorheol Microcirc. 2008;39:293-302.
    • (2008) Clin Hemorheol Microcirc , vol.39 , pp. 293-302
    • Leithauser, B.1    Zielske, D.2    Seyfert, U.T.3
  • 49
    • 0027267848 scopus 로고
    • Aprotinin reduces clopidogrel-induced prolongation of the bleeding time in the rat
    • Herbert JM, Bernat A, Maffrand JP. Aprotinin reduces clopidogrel-induced prolongation of the bleeding time in the rat. Thromb Res. 1993;71:433-441.
    • (1993) Thromb Res , vol.71 , pp. 433-441
    • Herbert, J.M.1    Bernat, A.2    Maffrand, J.P.3
  • 50
    • 0026063246 scopus 로고
    • Incomplete reversal of enoxaparin-induced bleeding by protamine sulfate
    • Bang CJ, Berstad A, Talstad I. Incomplete reversal of enoxaparin-induced bleeding by protamine sulfate. Haemostasis. 1991;21:155-160.
    • (1991) Haemostasis , vol.21 , pp. 155-160
    • Bang, C.J.1    Berstad, A.2    Talstad, I.3
  • 51
    • 0026460025 scopus 로고
    • Study on neutralization of low molecular weight heparin (LHG) by protamine sulfate and its neutralization characteristics
    • Sugiyama T, Itoh M, Ohtawa M, et al. Study on neutralization of low molecular weight heparin (LHG) by protamine sulfate and its neutralization characteristics. Thromb Res. 1992; 68:119-129.
    • (1992) Thromb Res , vol.68 , pp. 119-129
    • Sugiyama, T.1    Itoh, M.2    Ohtawa, M.3
  • 52
    • 34548361909 scopus 로고    scopus 로고
    • Recombinant activated factor VII effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography
    • Young G, Yonekawa KE, Nakagawa PA, et al. Recombinant activated factor VII effectively reverses the anticoagulant effects of heparin, enoxaparin, fondaparinux, argatroban, and bivalirudin ex vivo as measured using thromboelastography. Blood Coagul Fibrinolysis. 2007;18:547-553.
    • (2007) Blood Coagul Fibrinolysis , vol.18 , pp. 547-553
    • Young, G.1    Yonekawa, K.E.2    Nakagawa, P.A.3
  • 53
    • 0037069334 scopus 로고    scopus 로고
    • Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers
    • Bijsterveld NR, Moons AH, Boekholdt SM, et al. Ability of recombinant factor VIIa to reverse the anticoagulant effect of the pentasaccharide fondaparinux in healthy volunteers. Circulation. 2002;106:2550-2554.
    • (2002) Circulation , vol.106 , pp. 2550-2554
    • Bijsterveld, N.R.1    Moons, A.H.2    Boekholdt, S.M.3
  • 54
    • 59949091088 scopus 로고    scopus 로고
    • Rivaroxaban: A novel, oral, direct factorXa inhibitor
    • Abrams PJ, Emerson CR. Rivaroxaban: A novel, oral, direct factorXa inhibitor. Pharmacotherapy. 2009;29:167-181.
    • (2009) Pharmacotherapy , vol.29 , pp. 167-181
    • Abrams, P.J.1    Emerson, C.R.2
  • 55
    • 17844385569 scopus 로고    scopus 로고
    • New anticoagulants: Beyond heparin, low molecular weight heparin, and warfarin
    • Bates SM, Weitz JI. New anticoagulants: beyond heparin, low molecular weight heparin, and warfarin. Br J Pharmacol. 2005;144:1017-1028.
    • (2005) Br J Pharmacol , vol.144 , pp. 1017-1028
    • Bates, S.M.1    Weitz, J.I.2
  • 56
    • 77950014200 scopus 로고    scopus 로고
    • Pradaxa [package insert]. Germany: Boehringer Ingelheim; 2008
    • Pradaxa [package insert]. Germany: Boehringer Ingelheim; 2008.


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