Cytotoxicity and regenerative proliferation as the mode of action for Diuron-Induced urothelial carcinogenesis in the rat

Toxicological Sciences

Volumn 113, Issue 1, 2009, Pages 37-44

  Da Rocha, Mitscheli S ^a   Nascimento, Merielen G ^a   Cardoso, Ana Paula F ^a   De Lima, Patrícia L A ^a   Zelandi, Edneia A ^a   De Camargo, João Lauro V ^a   De Oliveira, Maria Luiza C S ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

Author keywords

Cytotoxicity; DNA cross link; Urinary bladder; Urinary crystals and precipitates; Urinary pH; Urothelial hyperplasia

Indexed keywords

AMMONIUM CHLORIDE; AMMONIUM MAGNESIUM PHOSPHATE; DIURON; DNA; HERBICIDE;

ACIDIFICATION; ANIMAL CELL; ANIMAL EUTHANASIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; CARCINOGENESIS; CELL DEATH; CELL PROLIFERATION; CELL REGENERATION; COMET ASSAY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DNA CROSS LINKING; GENOTOXICITY; IN VITRO STUDY; MALE; MICROSCOPY; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY; URINARY EXCRETION; URINE PH;

AMMONIUM CHLORIDE; ANIMALS; BODY WEIGHT; CARCINOGENS; CELL PROLIFERATION; CHO CELLS; COMET ASSAY; CRICETINAE; CRICETULUS; DIURON; DNA DAMAGE; HERBICIDES; HYDROGEN-ION CONCENTRATION; HYPERPLASIA; MAGNESIUM COMPOUNDS; MALE; NECROSIS; PHOSPHATES; RATS; RATS, WISTAR; REGENERATION; TIME FACTORS; URINARY BLADDER; URINARY BLADDER NEOPLASMS; URINARY CALCULI; UROTHELIUM;

ANIMALIA; CRICETULUS GRISEUS; RATTUS; RATTUS NORVEGICUS;

EID: 75249096094     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp241     Document Type: Article

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