Choline PET for monitoring early tumor response to photodynamic therapy

Journal of Nuclear Medicine

Volumn 51, Issue 1, 2010, Pages 130-138

  Fei, Baowei ^a   Wang, Hesheng ^b   Wu, Chunying ^c   Chiu, Song Mao ^c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Case Western Reserve University   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Choline molecular imaging; Photodynamic therapy (PDT); Prostate cancer; Small animal PET; Tumor response

Indexed keywords

CHOLINE C 11;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; TREATMENT RESPONSE; TUMOR GROWTH; TUMOR VOLUME;

ALGORITHMS; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; CHOLINE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INDOLES; ISOTOPE LABELING; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; POSITRON-EMISSION TOMOGRAPHY; PROSTATIC NEOPLASMS; RADIOPHARMACEUTICALS;

EID: 75149183221     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.067579     Document Type: Article

References (40)

1. Triesscheijn M, Baas P, Schellens JH, Stewart FA. Photodynamic therapy in oncology. Oncologist. 2006;11:1034-1044.
2. Oleinick NL, Morris RL, Belichenko I. The role of apoptosis in response to photodynamic therapy: what, where, why, and how. Photochem Photobiol Sci. 2002;1:1-21.
3. Miller JD, Baron ED, Scull H, et al. Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studies. Toxicol Appl Pharmacol. 2007;224:290-299.
4. Weersink RA, Bogaards A, Gertner M, et al. Techniques for delivery and monitoring of TOOKAD (WST09)-mediated photodynamic therapy of the prostate: clinical experience and practicalities. J Photochem Photobiol B. 2005;79:211-222.
5. Zaak D, Sroka R, Stocker S, et al. Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX: in vivo experiments on the dunning rat tumor model. Urol Int. 2004;72:196-202.
6. Moore CM, Nathan TR, Lees WR, et al. Photodynamic therapy using meso tetra hydroxy phenyl chlorin (mTHPC) in early prostate cancer. Lasers Surg Med. 2006;38:356-363.
7. Du KL, Mick R, Busch TM, et al. Preliminary results of interstitial motexafin lutetium-mediated PDT for prostate cancer. Lasers Surg Med. 2006;38:427-434.
8. Fei B, Wang H, Muzic RF Jr, et al. Deformable and rigid registration of MRI and microPET images for photodynamic therapy of cancer in mice. Med Phys. 2006;33:753-760.
9. Fei B, Muzic R, Lee Z, et al. Registration of micro-PET and high resolution MR images of mice for monitoring photodynamic therapy. Proc SPIE. 2004;5369:371-379.
10. Lapointe D, Brasseur N, Cadorette J, et al. High-resolution PET imaging for in vivo monitoring of tumor response after photodynamic therapy in mice. J Nucl Med. 1999;40:876-882.
11. Berard V, Rousseau JA, Cadorette J, et al. Dynamic imaging of transient metabolic processes by small-animal PET for the evaluation of photosensitizers in photodynamic therapy of cancer. J Nucl Med. 2006;47:1119-1126.
12. 99mTc-annexin V and its biologic evaluation for in vivo imaging of apoptosis after photodynamic therapy. J Nucl Med. 2003;44:650-656.
13. 64Cu-labeled streptavidin following pretargeting of phosphatidylserine with biotinylated annexin-V. Eur J Nucl Med Mol Imaging. 2007;34:247-258.
14. Lam M, Oleinick NL, Nieminen AL. Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells: reactive oxygen species and mitochondrial inner membrane permeabilization. J Biol Chem. 2001;276:47379-47386.
15. Kennedy EP, Weiss SB. The function of cytidine coenzymes in the biosynthesis of phospholipides. J Biol Chem. 1956;222:193-214.
16. Glunde K, Jacobs MA, Bhujwalla ZM. Choline metabolism in cancer: implications for diagnosis and therapy. Expert Rev Mol Diagn. 2006;6:821-829.
17. Katz-Brull R, Margalit R, Degani H. Differential routing of choline in implanted breast cancer and normal organs. Magn Reson Med. 2001;46:31-38.
18. Yoshimoto M, Waki A, Obata A, Furukawa T, Yonekura Y, Fujibayashi Y. Radiolabeled choline as a proliferation marker: comparison with radiolabeled acetate. Nucl Med Biol. 2004;31:859-865.
19. Lenkinski RE, Bloch BN, Liu F, et al. An illustration of the potential for mapping MRI/MRS parameters with genetic over-expression profiles in human prostate cancer. MAGMA. 2008;21:411-421.
20. 18F-labeled choline analogs as oncologic PET tracers. J Nucl Med. 2001;42:1805-1814.
21. Gillies RJ, Morse DL. In vivo magnetic resonance spectroscopy in cancer. Annu Rev Biomed Eng. 2005;7:287-326.
22. 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer. Cancer Res. 2001;61:110-117.
23. Oleinick NL, Antunez AR, Clay ME, Rihter BD, Kenney ME. New phthalocyanine photosensitizers for photodynamic therapy. Photochem Photobiol. 1993;57:242-247.
24. Pretlow TG, Delmoro CM, Dilley GG, Spadafora CG, Pretlow TP. Transplantation of human prostatic carcinoma into nude mice in Matrigel. Cancer Res. 1991;51:3814-3817.
25. Kaighn ME, Narayan KS, Ohnuki Y, Lechner JF, Jones LW. Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest Urol. 1979;17:16-23.
26. Fei B, Wang H, Meyers J, Feyes D, Oleinick NL, Duerk JL. High-field magnetic resonance imaging of the response of human prostate cancer to Pc4-based photodynamic therapy in an animal model. Lasers Surg Med. 2007;39:723-730.
27. 11C]choline. J Labelled Comp Radiopharm. 2000;43:195-203.
28. Ray SK, Karmakar S, Nowak MW, Banik NL. Inhibition of calpain and caspase-3 prevented apoptosis and preserved electrophysiological properties of voltage-gated and ligand-gated ion channels in rat primary cortical neurons exposed to glutamate. Neuroscience. 2006;139:577-595.
29. WhitacreCM, Satoh TH, Xue L, Gordon NH, Oleinick NL. Photodynamic therapy of human breast cancer xenografts lacking caspase-3. Cancer Lett. 2002;179: 43-49.
30. Colussi VC, Feyes DK, Mulvihill JW, et al. Phthalocyanine 4 (Pc 4) photodynamic therapy of human OVCAR-3 tumor xenografts. Photochem Photobiol. 1999;69: 236-241.
31. Whitacre CM, Feyes DK, Satoh T, et al. Photodynamic therapy with the phthalocyanine photosensitizer Pc 4 of SW480 human colon cancer xenografts in athymic mice. Clin Cancer Res. 2000;6:2021-2027.
32. George JE, Ahmad Y, Varghai D, et al. Pc 4 photodynamic therapy of U87-derived human glioma in the nude rat. Lasers Surg Med. 2005;36:383-389.
33. Egorin MJ, Zuhowski EG, Sentz DL, Dobson JM, Callery PS, Eiseman JL. Plasma pharmacokinetics and tissue distribution in CD2F1 mice of Pc4 (NSC 676418), a silicone phthalocyanine photodynamic sensitizing agent. Cancer Chemother Pharmacol. 1999;44:283-294.
34. Zhu TC, Finlay JC, Hahn SM. Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy. J Photochem Photobiol B. 2005;79:231-241.
35. Yu G, Durduran T, Zhou C, et al. Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy. Clin Cancer Res. 2005;11:3543-3552.
36. Li H, Standish BA, Mariampillai A, et al. Feasibility of interstitial Doppler optical coherence tomography for in vivo detection of microvascular changes during photodynamic therapy. Lasers Surg Med. 2006;38:754-761.
37. Zhou X, Pogue BW, Chen B, et al. Pretreatment photosensitizer dosimetry reduces variation in tumor response. Int J Radiat Oncol Biol Phys. 2006;64:1211-1220.
38. Sterenborg H, de Wolf J, Koning M, Kruijt B, van den Heuvel A, Robinson D. Phosphorescence-fluorescence ratio imaging for monitoring the oxygen status during photodynamic therapy. Opt Express. 2004;12:1873-1878.
39. Morris RL, Azizuddin K, Lam M, et al. Fluorescence resonance energy transfer reveals a binding site of a photosensitizer for photodynamic therapy. Cancer Res. 2003;63:5194-5197.
40. Hoch FL. Cardiolipins and biomembrane function. Biochim Biophys Acta. 1992; 1113:71-133.