Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species

Chemical Research in Toxicology

Volumn 23, Issue 1, 2010, Pages 171-183

  Fourches, Denis ^a   Barnes, Julie C ^b   Day, Nicola C ^b   Bradley, Paul ^b   Reed, Jane Z ^b   Tropsha, Alexander ^a  

^a University of North Carolina   (United States)

^b BioWisdom Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHOXYESTRADIOL; 4 AMINOBENZOIC ACID; 4 HYDROXYTAMOXIFEN; 5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; 5 BROMOURACIL; ACARBOSE; ACEBUTOLOL; ACENOCOUMAROL; ACETAMIDE; ACETAZOLAMIDE; ACETIC ACID; ACETOHEXAMIDE; ACETOHYDROXAMIC ACID; ACETRIZOIC ACID; ACETYLCHOLINE; ACETYLCYSTEINE; ACETYLSALICYLIC ACID; AZACITIDINE; CLEVUDINE; DEOXYGLUCOSE; FLOXURIDINE; FLUOROURACIL; HYDROXYCOLECALCIFEROL; MERCAPTOPURINE; METHYLTESTOSTERONE; PARACETAMOL; ROSCOVITINE; SUCCIMER; TRINITROTOLUENE; UNINDEXED DRUG;

ARTICLE; ASSERTIVENESS; CHEMICAL STRUCTURE; DRUG INDUCED DISEASE; EXTERNAL VALIDITY; HUMAN; INFORMATION SCIENCE; LINGUISTICS; LIVER INJURY; MEDLINE; NONHUMAN; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RODENT; SPECIES DIFFERENCE; TOXICITY; TOXICOLOGY; VALIDATION PROCESS;

ANIMALS; CLUSTER ANALYSIS; DATABASES, FACTUAL; DRUG-INDUCED LIVER INJURY; HUMANS; MEDLINE; MICE; MODELS, CHEMICAL; MOLECULAR CONFORMATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

RODENTIA;

EID: 75149175715     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx900326k     Document Type: Article

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